AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DPNB-ABT594
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates α4β2 over α7 nAChRs; used to study Ca²⁺ signaling in MHb.Formula:C31H46ClN3O11Colore e forma:SolidPeso molecolare:672.16AFDX384
CAS:AFDX384 is potent M2/M4 selective antagonist.Formula:C28H42N6O5SColore e forma:SolidPeso molecolare:574.74(S)-VQW-765
(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.Formula:C19H22N2OColore e forma:SolidPeso molecolare:294.39Mazaticol
CAS:<p>Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.</p>Formula:C21H27NO3S2Colore e forma:SolidPeso molecolare:405.57J-104129 fumarate
CAS:J-104129 fumarate is a potent M3 muscarinic receptor antagonist.Formula:C28H40N2O6Colore e forma:SolidPeso molecolare:500.63BMS-902483
CAS:BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.Formula:C18H20N4OPurezza:98%Colore e forma:SolidPeso molecolare:308.38RLH 033
CAS:RLH 033 is a selective ligand for the sigma 1 recognition site.Formula:C25H31ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:458.98Talsaclidine
CAS:Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.Formula:C10H15NOPurezza:98%Colore e forma:SolidPeso molecolare:165.23A-85380 HCl
CAS:A-85380 is an agonist of nicotinic acetylcholine receptor.Formula:C9H14Cl2N2OColore e forma:SolidPeso molecolare:237.13Phenglutarimid
CAS:Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H24N2O2Purezza:98%Colore e forma:SolidPeso molecolare:288.38Pirenzepine
CAS:Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.Formula:C19H21N5O2Colore e forma:SolidPeso molecolare:351.4TC-T 6000
CAS:TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.Formula:C26H48N8O2Purezza:98.14%Colore e forma:SolidPeso molecolare:504.71ENS-163 phosphate
CAS:Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.Formula:C11H19N2O5PSPurezza:98%Colore e forma:SolidPeso molecolare:322.32TMPH hydrochloride
CAS:neuronal nicotinic ACh receptors (nAChRs) antagonistFormula:C16H32ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:305.889-CP-Ade Mesylate
CAS:9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.Formula:C11H17N5O3SPurezza:99.81%Colore e forma:SolidPeso molecolare:299.35Arecaidine but-2-ynyl ester tosylate
CAS:mAChR M2 agonistFormula:C18H23NO5SPurezza:98%Colore e forma:SolidPeso molecolare:365.44GSK575594A
CAS:GSK575594A is a selective agonist of GPR55.Formula:C24H23F2N3O3SColore e forma:SolidPeso molecolare:471.52(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Formula:C22H31NO3Colore e forma:SolidPeso molecolare:357.49AC-42
CAS:<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Formula:C20H31NOColore e forma:SolidPeso molecolare:301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS:α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).Formula:C25H30O6Colore e forma:SolidPeso molecolare:426.5Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Formula:C22H27NOPurezza:98%Colore e forma:SolidPeso molecolare:321.46Anabasine hydrochloride
CAS:neuronal nicotinic ACh receptor partial agonistFormula:C10H15ClN2Purezza:98%Colore e forma:White To Off-White SolidPeso molecolare:198.693Flupyrimin
CAS:Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].Formula:C13H9ClF3N3OColore e forma:SolidPeso molecolare:315.68Adenylyl cyclase type 2 agonist-1
CAS:Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.Formula:C27H17BrClNO5Colore e forma:SolidPeso molecolare:550.78RJR-2403 oxalate
CAS:RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.Formula:C14H18N2O4Purezza:98%Colore e forma:SolidPeso molecolare:278.308Bibn 140
CAS:Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.Formula:C32H44N4O3Purezza:98%Colore e forma:SolidPeso molecolare:532.72AZD 0328
CAS:AZD 0328 is a nicotinic receptor agonist for α7 neurons.Formula:C13H16N2OColore e forma:SolidPeso molecolare:216.28Nelonicline citrate
CAS:Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.Formula:C23H27N3O8SColore e forma:SolidPeso molecolare:505.54N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Formula:C13H17N5Purezza:98%Colore e forma:SolidPeso molecolare:243.31Bradanicline
CAS:Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.Formula:C22H23N3O2Colore e forma:SolidPeso molecolare:361.44mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Formula:C23H25IN2O2Purezza:98%Colore e forma:SolidPeso molecolare:488.364-DAMP
CAS:4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.Formula:C21H26INO2Purezza:98%Colore e forma:SolidPeso molecolare:451.34Asoxime dichloride
CAS:Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.Formula:C14H16Cl2N4O3Purezza:99.75% - 99.86%Colore e forma:SolidPeso molecolare:359.21Camylofine
CAS:Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.Formula:C19H32N2O2·2HClPurezza:98%Colore e forma:SolidPeso molecolare:393.4(Rac)-VU 6008667
CAS:(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.Formula:C24H17ClF2N2O2Purezza:99.82%Colore e forma:SolidPeso molecolare:438.85Pentolinium Tartrate
CAS:Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.Formula:C15H32N2·2C4H5O6Purezza:98%Colore e forma:SolidPeso molecolare:538.6AF-DX 384 free base
CAS:AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.Formula:C27H38N6O2Purezza:98%Colore e forma:SolidPeso molecolare:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Formula:C11H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:192.26CB-6673567
CAS:CB-6673567 is a selective inhibitor of adenylyl cyclase.Formula:C19H14N4O3Colore e forma:SolidPeso molecolare:346.34NGX-267
CAS:NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.Formula:C10H18N2OSColore e forma:SolidPeso molecolare:214.33Dac 5945
CAS:DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.Formula:C19H30ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:351.91Hexocyclium metilsulfate
CAS:Hexocyclium metilsulfate has anti-gastric secretory effects in humans.Formula:C21H36N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:428.59GS 283
CAS:GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.Formula:C17H17NO3Colore e forma:SolidPeso molecolare:283.32(R)-VU 6008667
CAS:(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).Formula:C24H17ClF2N2O2Colore e forma:SolidPeso molecolare:438.85Anisodine hydrobromide
CAS:Anisodine hydrobromide is an inhibitor of adenosine kinase.Formula:C17H22BrNO5Colore e forma:White Crystals Or Crystalline PowderPeso molecolare:400.27Btm 1042
CAS:Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.Formula:C21H26ClN3OSColore e forma:SolidPeso molecolare:403.97Hyoscyamine hydrobromide
CAS:Hyoscyamine hydrobromide is an agent of anticholinergic.Formula:C17H24BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:370.28Sazetidine A dihydrochloride
CAS:α4β2 nicotinic acetylcholine receptor ligandFormula:C15H21ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:296.79FR 121196
CAS:FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.Formula:C12H16FN3O3SColore e forma:SolidPeso molecolare:301.34Prifuroline
CAS:Prifuroline is an agent of antiarrhythmic.Formula:C14H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:228.29Epibatidine 2HCl
CAS:Epibatidine 2HCl is a potent nicotinic agonist.Formula:C11H15Cl3N2Purezza:98%Colore e forma:SolidPeso molecolare:281.61Flutropium Bromide
CAS:Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.Formula:C24H29BrFNO3Purezza:98%Colore e forma:SolidPeso molecolare:478.39Vesamicol
CAS:Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.Formula:C17H25NOPurezza:98%Colore e forma:SolidPeso molecolare:259.39Siltenzepine
CAS:Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.Formula:C19H20ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:389.83L 858051
CAS:L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.Formula:C29H48N2O7Colore e forma:SolidPeso molecolare:536.7S16961
CAS:S16961 (S169611) is an agonist of nicotinic receptor.Formula:C41H71NO6Purezza:99.69%Colore e forma:SolidPeso molecolare:674.01DBO-83
CAS:DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.Formula:C10H15Cl3N4Purezza:98%Colore e forma:SolidPeso molecolare:297.61ADX-10061
CAS:ADX-10061 is a dopamine D1 receptor antagonist.Formula:C19H20N2O4Colore e forma:SolidPeso molecolare:340.37Afacifenacin
CAS:Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.Formula:C27H26F3N3O2Purezza:99.83%Colore e forma:SolidPeso molecolare:481.51JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Formula:C16H21FN2O2Colore e forma:SolidPeso molecolare:292.35Tarafenacin D-tartrate
CAS:Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formula:C25H26F4N2O8Purezza:99.86%Colore e forma:SolidPeso molecolare:558.48Tebanicline tosylate
CAS:Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.Formula:C16H19ClN2O4SPurezza:98%Colore e forma:SolidPeso molecolare:370.85Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Formula:C20H28ClNPurezza:98%Colore e forma:SolidPeso molecolare:317.9YM-46303
CAS:YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia inFormula:C20H23ClN2O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:358.86CHF5407
CAS:CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFormula:C27H25BrF4N2O3SPurezza:99.54% - >99.99%Colore e forma:SolidPeso molecolare:613.46UP202-56
CAS:UP202-56 is an adenosinergic agonist and is an adenosine analog.Formula:C33H37N7O4Purezza:98%Colore e forma:SolidPeso molecolare:595.69CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Formula:C14H12N2O2Purezza:99.59%Colore e forma:SolidPeso molecolare:240.26KL8604166
CAS:KL8604166 (UCB-11056) is a potential puzzle compound.UCB-11056 amplifies the formation of inducible cyclic AMP in rat brain tissue.Formula:C12H21N5O2Purezza:99.21%Colore e forma:SolidPeso molecolare:267.33PF-06767832
CAS:PF-06767832: selective M1 PAM (EC50=60 nM), no M2-M5 activity, good CNS penetration, but has GI and cardiovascular risks.Formula:C22H23N3O3SColore e forma:SolidPeso molecolare:409.5Hadacidin
CAS:Hadacidin is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Formula:C3H5NO4Colore e forma:SolidPeso molecolare:119.08Glucagon Receptor Antagonist I
CAS:Glucagon antagonist I blocks the GCGR (IC50=181 nM), stops glucagon-induced glycogenolysis, and lowers glucose in glucagon-treated humanized mice.Formula:C20H30N2OSColore e forma:SolidPeso molecolare:346.53RJR-2429
CAS:RJR-2429 is a potent AChR agonist.Formula:C12H16N2Colore e forma:SolidPeso molecolare:188.27CC4
CAS:Selective α6β2/α4β2 partial agonist; Ki: 12/26nM (rat); poor α3β4/α7 affinity; stimulates dopamine release; reduces nicotine self-admin in rats.Formula:C24H30N4O2Colore e forma:SolidPeso molecolare:406.52Hadacidin sodium
CAS:Hadacidin sodium is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Formula:C3H4NNaO4Colore e forma:SolidPeso molecolare:141.06Dexetimide HCl
CAS:Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.Formula:C23H27ClN2O2Colore e forma:SolidPeso molecolare:398.93(E/Z)-VU0029767
CAS:VU0029767 enhances M1 muscarinic receptor function, increasing acetylcholine potency and efficacy.Formula:C21H21N3O3Colore e forma:SolidPeso molecolare:363.41Octamylamine sulfamate
CAS:Octamylamine sulfamate is a P450 inhibitor.Formula:C13H32N2O3SColore e forma:SolidPeso molecolare:296.47Cimetropium Bromide
CAS:Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.Formula:C21H28BrNO4Colore e forma:SolidPeso molecolare:438.36Metanicotine
CAS:Metanicotine is a selective nicotinic agonist with antinociceptive properties.Formula:C10H14N2Colore e forma:SolidPeso molecolare:162.23Caramiphen hydrochloride
CAS:Caramiphen hydrochloride: antimuscarinic, anticholinergic, NMDA receptor antagonist salt.Formula:C18H28ClNO2Colore e forma:SolidPeso molecolare:325.88TC-1698 dihydrochloride
CAS:TC-1698 dihydrochloride: selective α7 nicotinic agonist, with some β-receptor activity; neuroprotectant.Formula:C13H20Cl2N2Colore e forma:SolidPeso molecolare:275.22Octamylamine hydrochloride
CAS:Octamylamine hydrochloride is a P450 inhibitor.Formula:C13H30ClNColore e forma:SolidPeso molecolare:235.84Neopterin, L-erythro-
CAS:Neopterin, L-erythro- can be used as a cholinergic receptor.Formula:C9H11N5O4Colore e forma:SolidPeso molecolare:253.21Methacholine iodide
CAS:Methacholine iodide is a muscarinic acetylcholine receptor agonist.Formula:C8H18INO2Colore e forma:SolidPeso molecolare:287.14GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Colore e forma:SolidPeso molecolare:347.37Meseclazone
CAS:<p>Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.</p>Formula:C11H10ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:239.65AQ-RA 721
CAS:AQ-RA 721 is a selective muscarinic antagonist with high affinity for M1- and M3-receptors. AQ-RA 721 may be used as a bronchodilator.Formula:C22H23N3O2Colore e forma:SolidPeso molecolare:361.44AZD-9164 bromide
CAS:AMG-221, a selective 11β-HSD1 inhibitor, suppresses enzyme activity, lowers glucose/insulin, and reduces weight in obese mice.Formula:C29H38BrFN2O2Colore e forma:SolidPeso molecolare:545.53UH-AH 37
CAS:UH-AH 37 is a antagonist of human muscarinic acetylcholine receptor.Formula:C21H23Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:420.33DAU 5884 HCl
CAS:DAU 5884 HCl is an M3 receptor antagonistFormula:C17H21N3O3Colore e forma:SolidPeso molecolare:315.37Ethybenztropine HBr
CAS:Ethybenztropine HBr is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.Formula:C22H28BrNOColore e forma:SolidPeso molecolare:402.37Atropine Oxide Hydrochloride
CAS:Atropine Oxide, a derivative of anticholinergic Atropine, treats poisonings, slow heart rate, and reduces saliva during surgery.Formula:C17H24ClNO4Colore e forma:SolidPeso molecolare:341.83YM-58790
CAS:YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.Formula:C27H31N3O2Purezza:99.87%Colore e forma:SoildPeso molecolare:429.55UB 165 fumarate
CAS:<p>UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.</p>Formula:C17H19ClN2O4Purezza:99.72%Colore e forma:SolidPeso molecolare:350.8Metixene hydrochloride
CAS:Metixene hydrochloride is an anticholinergic antiparkinsonian agent.Formula:C20H24ClNSPurezza:98%Colore e forma:SolidPeso molecolare:345.93Darenzepine
CAS:Darenzepine is a muscarinic receptor inhibitor.Formula:C21H21N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:347.41CDD0102
CAS:CDD0102 is a potent agonist of M1 Muscarinic receptor.Formula:C8H12N4OPurezza:98%Colore e forma:SolidPeso molecolare:180.215-Iodo-A-85380 dihydrochloride
CAS:α4β2 and α6β2 nicotinic acetylcholine receptors agonistFormula:C9H13Cl2IN2OPurezza:98%Colore e forma:SolidPeso molecolare:363.02Dimethyl-W84 (dibromide)
CAS:<p>Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.</p>Formula:C34H48Br2N4O4Colore e forma:SolidPeso molecolare:736.59LY 2087101
CAS:Allosteric potentiator of α7, α4β2 and α4β4 nAChRsFormula:C15H11FN2OS2Purezza:98%Colore e forma:SolidPeso molecolare:318.39
