AChR
Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.
Trovati 617 prodotti di "AChR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DPNB-ABT594
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates α4β2 over α7 nAChRs; used to study Ca²⁺ signaling in MHb.Formula:C31H46ClN3O11Colore e forma:SolidPeso molecolare:672.16AFDX384
CAS:AFDX384 is potent M2/M4 selective antagonist.Formula:C28H42N6O5SColore e forma:SolidPeso molecolare:574.74(S)-VQW-765
(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.Formula:C19H22N2OColore e forma:SolidPeso molecolare:294.39Mazaticol
CAS:<p>Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.</p>Formula:C21H27NO3S2Colore e forma:SolidPeso molecolare:405.57J-104129 fumarate
CAS:J-104129 fumarate is a potent M3 muscarinic receptor antagonist.Formula:C28H40N2O6Colore e forma:SolidPeso molecolare:500.63BMS-902483
CAS:BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.Formula:C18H20N4OPurezza:98%Colore e forma:SolidPeso molecolare:308.38RLH 033
CAS:RLH 033 is a selective ligand for the sigma 1 recognition site.Formula:C25H31ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:458.98Talsaclidine
CAS:Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.Formula:C10H15NOPurezza:98%Colore e forma:SolidPeso molecolare:165.23A-85380 HCl
CAS:A-85380 is an agonist of nicotinic acetylcholine receptor.Formula:C9H14Cl2N2OColore e forma:SolidPeso molecolare:237.13Phenglutarimid
CAS:Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.Formula:C17H24N2O2Purezza:98%Colore e forma:SolidPeso molecolare:288.38Pirenzepine
CAS:Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.Formula:C19H21N5O2Colore e forma:SolidPeso molecolare:351.4TC-T 6000
CAS:TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.Formula:C26H48N8O2Purezza:98.14%Colore e forma:SolidPeso molecolare:504.71ENS-163 phosphate
CAS:Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.Formula:C11H19N2O5PSPurezza:98%Colore e forma:SolidPeso molecolare:322.32TMPH hydrochloride
CAS:neuronal nicotinic ACh receptors (nAChRs) antagonistFormula:C16H32ClNO2Purezza:98%Colore e forma:SolidPeso molecolare:305.889-CP-Ade Mesylate
CAS:9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.Formula:C11H17N5O3SPurezza:99.81%Colore e forma:SolidPeso molecolare:299.35Arecaidine but-2-ynyl ester tosylate
CAS:mAChR M2 agonistFormula:C18H23NO5SPurezza:98%Colore e forma:SolidPeso molecolare:365.44GSK575594A
CAS:GSK575594A is a selective agonist of GPR55.Formula:C24H23F2N3O3SColore e forma:SolidPeso molecolare:471.52(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Formula:C22H31NO3Colore e forma:SolidPeso molecolare:357.49AC-42
CAS:<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Formula:C20H31NOColore e forma:SolidPeso molecolare:301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS:α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).Formula:C25H30O6Colore e forma:SolidPeso molecolare:426.5Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Formula:C22H27NOPurezza:98%Colore e forma:SolidPeso molecolare:321.46Anabasine hydrochloride
CAS:neuronal nicotinic ACh receptor partial agonistFormula:C10H15ClN2Purezza:98%Colore e forma:White To Off-White SolidPeso molecolare:198.693Flupyrimin
CAS:Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].Formula:C13H9ClF3N3OColore e forma:SolidPeso molecolare:315.68Adenylyl cyclase type 2 agonist-1
CAS:Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.Formula:C27H17BrClNO5Colore e forma:SolidPeso molecolare:550.78RJR-2403 oxalate
CAS:RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.Formula:C14H18N2O4Purezza:98%Colore e forma:SolidPeso molecolare:278.308Bibn 140
CAS:Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.Formula:C32H44N4O3Purezza:98%Colore e forma:SolidPeso molecolare:532.72AZD 0328
CAS:AZD 0328 is a nicotinic receptor agonist for α7 neurons.Formula:C13H16N2OColore e forma:SolidPeso molecolare:216.28Nelonicline citrate
CAS:Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.Formula:C23H27N3O8SColore e forma:SolidPeso molecolare:505.54N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Formula:C13H17N5Purezza:98%Colore e forma:SolidPeso molecolare:243.31Bradanicline
CAS:Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.Formula:C22H23N3O2Colore e forma:SolidPeso molecolare:361.44mAChr-in-1
CAS:mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).Formula:C23H25IN2O2Purezza:98%Colore e forma:SolidPeso molecolare:488.364-DAMP
CAS:4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.Formula:C21H26INO2Purezza:98%Colore e forma:SolidPeso molecolare:451.34Asoxime dichloride
CAS:Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.Formula:C14H16Cl2N4O3Purezza:99.75% - 99.86%Colore e forma:SolidPeso molecolare:359.21Camylofine
CAS:Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.Formula:C19H32N2O2·2HClPurezza:98%Colore e forma:SolidPeso molecolare:393.4(Rac)-VU 6008667
CAS:(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.Formula:C24H17ClF2N2O2Purezza:99.82%Colore e forma:SolidPeso molecolare:438.85Pentolinium Tartrate
CAS:Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.Formula:C15H32N2·2C4H5O6Purezza:98%Colore e forma:SolidPeso molecolare:538.6AF-DX 384 free base
CAS:AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.Formula:C27H38N6O2Purezza:98%Colore e forma:SolidPeso molecolare:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Formula:C11H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:192.26CB-6673567
CAS:CB-6673567 is a selective inhibitor of adenylyl cyclase.Formula:C19H14N4O3Colore e forma:SolidPeso molecolare:346.34NGX-267
CAS:NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.Formula:C10H18N2OSColore e forma:SolidPeso molecolare:214.33Dac 5945
CAS:DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.Formula:C19H30ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:351.91Hexocyclium metilsulfate
CAS:Hexocyclium metilsulfate has anti-gastric secretory effects in humans.Formula:C21H36N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:428.59GS 283
CAS:GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.Formula:C17H17NO3Colore e forma:SolidPeso molecolare:283.32(R)-VU 6008667
CAS:(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).Formula:C24H17ClF2N2O2Colore e forma:SolidPeso molecolare:438.85Anisodine hydrobromide
CAS:Anisodine hydrobromide is an inhibitor of adenosine kinase.Formula:C17H22BrNO5Colore e forma:White Crystals Or Crystalline PowderPeso molecolare:400.27Btm 1042
CAS:Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.Formula:C21H26ClN3OSColore e forma:SolidPeso molecolare:403.97Hyoscyamine hydrobromide
CAS:Hyoscyamine hydrobromide is an agent of anticholinergic.Formula:C17H24BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:370.28Sazetidine A dihydrochloride
CAS:α4β2 nicotinic acetylcholine receptor ligandFormula:C15H21ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:296.79FR 121196
CAS:FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.Formula:C12H16FN3O3SColore e forma:SolidPeso molecolare:301.34Prifuroline
CAS:Prifuroline is an agent of antiarrhythmic.Formula:C14H16N2OPurezza:98%Colore e forma:SolidPeso molecolare:228.29
