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AChR

AChR

Gli inibitori del recettore dell'acetilcolina (AChR) sono composti che bloccano l'attività dei recettori dell'acetilcolina, fondamentali per la neurotrasmissione nei sistemi nervoso centrale e periferico. Gli AChR svolgono un ruolo cruciale nella contrazione muscolare, nella memoria e nelle funzioni cognitive. Gli inibitori degli AChR vengono utilizzati per studiare condizioni come la miastenia grave, l'Alzheimer e altri disturbi neurologici. Modulando l'attività degli AChR, questi inibitori possono aiutare a svelare le complessità della segnalazione colinergica nel cervello. Presso CymitQuimica, offriamo una gamma di inibitori degli AChR per supportare la tua ricerca in neuroscienze, farmacologia e malattie neurodegenerative.

Trovati 617 prodotti di "AChR"

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  • Navafenterol saccharinate
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    Navafenterol saccharinate

    CAS:
    AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).
    Formula:C45H47N7O9S3
    Colore e forma:Solid
    Peso molecolare:926.09

    Ref: TM-T30265

  • Logo CymitQuimica
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    Irsogladine maleate

    CAS:
    Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    Formula:C9H7Cl2N5
    Colore e forma:Solid
    Peso molecolare:256.09

    Ref: TM-PDK0375

  • trans-Cevimeline hydrochloride
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    trans-Cevimeline hydrochloride

    CAS:
    <p>AF 102A hydrochloride is a biochemical.</p>
    Formula:C10H18ClNOS
    Colore e forma:Solid
    Peso molecolare:235.77

    Ref: TM-T29681

  • Hydroxybupropion
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    Hydroxybupropion

    CAS:
    Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).
    Formula:C13H18ClNO2
    Purezza:99.73%
    Colore e forma:Off-White Solid
    Peso molecolare:255.74

    Ref: TM-T11588

  • Pozanicline hydrochloride
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    Pozanicline hydrochloride

    Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.
    Formula:C11H17ClN2O
    Purezza:97.13% - 99.81%
    Colore e forma:Solid
    Peso molecolare:228.72

    Ref: TM-T16563L

  • M 8218
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    M 8218

    CAS:
    M 8218 is a bioactive chemical.
    Formula:C20H29NO2
    Colore e forma:Solid
    Peso molecolare:315.45

    Ref: TM-T33111

  • bPiDDB
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    bPiDDB

    CAS:
    <p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>
    Formula:C24H38Br2N2
    Purezza:98.72%
    Colore e forma:Solid
    Peso molecolare:514.38

    Ref: TM-T37818

  • Migrastatin
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    Migrastatin

    CAS:
    Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic
    Formula:C27H39NO7
    Colore e forma:Solid
    Peso molecolare:489.609

    Ref: TM-T35616

  • M4 mAChR agonist-1 
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    M4 mAChR agonist-1 

    CAS:
    <p>M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 &gt;10 μM).</p>
    Formula:C14H18N4OS
    Purezza:99.14%
    Colore e forma:Solid
    Peso molecolare:290.38

    Ref: TM-T9889

  • VU6028418
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    VU6028418

    CAS:
    VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).
    Colore e forma:Solid

    Ref: TM-T71675

  • Logo CymitQuimica
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    LtIA-F

    LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.
    Formula:C86H121N25O22S4
    Colore e forma:Solid
    Peso molecolare:1985.31

    Ref: TM-T75355

  • 5-AMAM-2-CP
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    5-AMAM-2-CP

    CAS:
    <p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>
    Formula:C9H11ClN2O
    Colore e forma:Solid
    Peso molecolare:198.65

    Ref: TM-T74086

  • R-(+)-Cotinine
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    R-(+)-Cotinine

    CAS:
    <p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>
    Formula:C10H12N2O
    Colore e forma:Solid
    Peso molecolare:176.22

    Ref: TM-T75309

  • Epiboxidine hydrochloride
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    Epiboxidine hydrochloride

    CAS:
    Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.
    Formula:C10H15ClN2O
    Colore e forma:Solid
    Peso molecolare:214.69

    Ref: TM-T74131

  • [D-Trp7,9,10]-Substance P
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    [D-Trp7,9,10]-Substance P

    CAS:
    <p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>
    Formula:C79H105N21O13S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1588.89

    Ref: TM-TP1932

  • PF-06827443
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    PF-06827443

    PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.
    Formula:C24H24N2O4
    Colore e forma:Solid
    Peso molecolare:404.47

    Ref: TM-T28377

  • Perlapine
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    Perlapine

    CAS:
    Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).
    Formula:C19H21N3
    Colore e forma:Solid
    Peso molecolare:291.39

    Ref: TM-T33937

  • Anagyrine hydrochloride
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    Anagyrine hydrochloride

    CAS:
    <p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>
    Formula:C15H21ClN2O
    Colore e forma:Solid
    Peso molecolare:280.79

    Ref: TM-T73856

  • Guanylyl Imidodiphosphate (lithium salt)
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    Guanylyl Imidodiphosphate (lithium salt)

    CAS:
    Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.
    Formula:C10H13Li4N6O13P3
    Colore e forma:Solid
    Peso molecolare:545.93

    Ref: TM-T36009

  • G-Protein antagonist peptide
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    G-Protein antagonist peptide

    CAS:
    <p>Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.</p>
    Formula:C57H64N12O9S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1093.27

    Ref: TM-TP1902