PAI-1
Il Plasminogen Activator Inhibitor-1 (PAI-1) è un inibitore delle serin proteasi che regola la fibrinolisi inibendo l'attivatore tissutale del plasminogeno (tPA) e l'urochinasi (uPA). Livelli elevati di PAI-1 sono associati a un aumento del rischio di trombosi, malattie cardiovascolari e sindrome metabolica. Gli inibitori di PAI-1 sono oggetto di ricerca per il loro potenziale nel trattamento di queste condizioni. Presso CymitQuimica, offriamo inibitori di PAI-1 per supportare la tua ricerca in ematologia, salute cardiovascolare e malattie metaboliche.
Trovati 26 prodotti di "PAI-1"
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Formula:C32H47N5O6SPurezza:99.41%Colore e forma:SolidPeso molecolare:629.81Angstrom6
CAS:<p>Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade</p>Formula:C39H62N10O15Purezza:99.36%Colore e forma:SolidPeso molecolare:910.97CT140
<p>CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.</p>Colore e forma:Odour LiquidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formula:C14H26Cl2N6O5Colore e forma:SolidPeso molecolare:428.13417Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Colore e forma:SolidUK140
<p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>Formula:C72H105N19O25S3Colore e forma:SolidPeso molecolare:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Formula:C77H118N26O25S3Colore e forma:SolidPeso molecolare:1904.116-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Formula:C6H13NO2Colore e forma:Fine White Crystalline Powder SolidPeso molecolare:131.17Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Formula:C18H20O5Purezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:316.35TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formula:C21H17ClN2O6Purezza:97.62% - 99.09%Colore e forma:SolidPeso molecolare:428.82Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formula:C24H16F3NO4Purezza:99.16% - 99.93%Colore e forma:SolidPeso molecolare:439.38Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Formula:C16H20O6Purezza:99.8% - 99.85%Colore e forma:SolidPeso molecolare:308.33TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Formula:C28H27ClN3NaO5Purezza:98.8% - 99.74%Colore e forma:SolidPeso molecolare:543.98TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Formula:C24H20N2O6S4Purezza:96.91%Colore e forma:SolidPeso molecolare:560.69UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Formula:C14H16ClN5O4SPurezza:95.81% - 99.77%Colore e forma:SolidPeso molecolare:385.83MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Formula:C10H10F3N3O3Colore e forma:SolidPeso molecolare:277.20SK-216
CAS:SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.Formula:C29H29NNa2O6Purezza:98.29%Colore e forma:SolidPeso molecolare:533.52UK-371804 HCl
CAS:UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-Formula:C14H17Cl2N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:422.29Diaplasinin
CAS:Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.Formula:C32H31N5OPurezza:99.02%Colore e forma:SolidPeso molecolare:501.62Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFormula:C28H27NO3Purezza:99.21%Colore e forma:SolidPeso molecolare:425.52AZ3976
CAS:<p>AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.</p>Formula:C15H19N5O3Purezza:98.14%Colore e forma:SolidPeso molecolare:317.34PPACK
CAS:<p>PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.</p>Formula:C21H31ClN6O3Purezza:98%Colore e forma:SolidPeso molecolare:450.96GW-6604
CAS:<p>GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.</p>Formula:C19H14N4Purezza:99.6%Colore e forma:SolidPeso molecolare:298.34ZK824190
CAS:<p>ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.</p>Formula:C22H20F2N2O4Purezza:98.84%Colore e forma:SolidPeso molecolare:414.4BT-114143
CAS:BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.Formula:C8H11N2O3PColore e forma:SolidPeso molecolare:214.158GGACK
CAS:GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Formula:C14H25ClN6O5Peso molecolare:392.84
