Cellule staminali
Gli inibitori delle cellule staminali sono composti che mirano specificamente alle cellule staminali e alle loro vie di segnalazione, influenzando la loro capacità di autorinnovarsi e differenziarsi. Questi inibitori sono cruciali nella ricerca focalizzata sul controllo del comportamento delle cellule staminali, sulla comprensione dei processi di sviluppo e sullo sviluppo di terapie per malattie come il cancro, dove si ritiene che le cellule staminali svolgano un ruolo chiave. Presso CymitQuimica, offriamo una varietà di inibitori delle cellule staminali per supportare la tua ricerca in medicina rigenerativa, biologia dello sviluppo e oncologia.
Trovati 467 prodotti di "Cellule staminali"
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exo-IWR-1
CAS:<p>exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin</p>Formula:C25H19N3O3Purezza:97.41%Colore e forma:SolidPeso molecolare:409.44YO-01027
CAS:<p>YO-01027 (DBZ) is a potent γ-secretase inhibitor.</p>Formula:C26H23F2N3O3Purezza:97.21% - 99.58%Colore e forma:SolidPeso molecolare:463.48GNF4877
CAS:<p>GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.</p>Formula:C25H27FN6O4Purezza:98.68% - 99.40%Colore e forma:SolidPeso molecolare:494.52WHI-P97
CAS:WHI-P97 is a rationally designed potent inhibitor of JAK-3.Formula:C16H13Br2N3O3Purezza:99.93%Colore e forma:SolidPeso molecolare:455.1Belumosudil
CAS:Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formula:C26H24N6O2Purezza:97.64% - 98.59%Colore e forma:SolidPeso molecolare:452.51(E/Z)-GSK-3β inhibitor 1
CAS:(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurezza:98.60%Colore e forma:SolidPeso molecolare:222.24Wnt pathway activator 1
CAS:Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Formula:C18H16O4Purezza:99.93%Colore e forma:SolidPeso molecolare:296.32S3I-201
CAS:S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.Formula:C16H15NO7SPurezza:97.83%Colore e forma:SolidPeso molecolare:365.36IHR-1
CAS:IHR-1, a Smo inhibitor (IC50 7.6 nM), blocks Hedgehog pathway, not Wnt/Notch, and prevents Smo in primary cilium.Formula:C20H12Cl4N2O2Purezza:97.02%Colore e forma:SolidPeso molecolare:454.13Avagacestat
CAS:Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,Formula:C20H17ClF4N4O4SPurezza:98.87% - 99.73%Colore e forma:SolidPeso molecolare:520.89MRT-14
CAS:MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.Formula:C24H24N4O5Purezza:99.54%Colore e forma:SolidPeso molecolare:448.47BDP5290
CAS:BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)Formula:C17H18ClN7OPurezza:97.22%Colore e forma:SolidPeso molecolare:371.82Lats-IN-1
CAS:Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.Formula:C18H14N4OSPurezza:97.54% - 99.79%Colore e forma:SolidPeso molecolare:334.39LY3200882
CAS:LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).Formula:C24H29N5O3Purezza:99.46% - 99.63%Colore e forma:SolidPeso molecolare:435.52WAY 316606
CAS:WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt.Formula:C18H19F3N2O4S2Purezza:99.65%Colore e forma:SolidPeso molecolare:448.48XMU-MP-1
CAS:<p>XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!</p>Formula:C17H16N6O3S2Purezza:99.68% - 99.79%Colore e forma:SolidPeso molecolare:416.48Crenigacestat
CAS:Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.Formula:C22H23F3N4O4Purezza:97.27% - 98.99%Colore e forma:SolidPeso molecolare:464.44Fosciclopirox
CAS:Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entireFormula:C13H20NO6PPurezza:99.83%Colore e forma:SolidPeso molecolare:317.27Jagged-1 (188-204) TFA(219127-21-6 free base)
Jagged-1 (188-204) TFA, a JAG-1 skin protein fragment, induces epidermal maturation and keratinocyte stratification.Formula:C95H128F3N25O28S3Purezza:99.48%Colore e forma:SolidPeso molecolare:2221.37SKL2001
CAS:SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formula:C14H14N4O3Purezza:97.46% - 99.99%Colore e forma:SolidPeso molecolare:286.29
