Cellule staminali
Gli inibitori delle cellule staminali sono composti che mirano specificamente alle cellule staminali e alle loro vie di segnalazione, influenzando la loro capacità di autorinnovarsi e differenziarsi. Questi inibitori sono cruciali nella ricerca focalizzata sul controllo del comportamento delle cellule staminali, sulla comprensione dei processi di sviluppo e sullo sviluppo di terapie per malattie come il cancro, dove si ritiene che le cellule staminali svolgano un ruolo chiave. Presso CymitQuimica, offriamo una varietà di inibitori delle cellule staminali per supportare la tua ricerca in medicina rigenerativa, biologia dello sviluppo e oncologia.
Trovati 467 prodotti di "Cellule staminali"
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TDZD-8
CAS:<p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>Formula:C10H10N2O2SPurezza:97.13% - 99.61%Colore e forma:White SolidPeso molecolare:222.26Teplinovivint
CAS:Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathyFormula:C25H26N6O2Purezza:97.21%Colore e forma:SolidPeso molecolare:442.51GSK429286A
CAS:<p>GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).</p>Formula:C21H16F4N4O2Purezza:97.68% - 98.49%Colore e forma:SolidPeso molecolare:432.37BDP5290
CAS:BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)Formula:C17H18ClN7OPurezza:97.22%Colore e forma:SolidPeso molecolare:371.82AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purezza:97.72% - 99.75%Colore e forma:SolidPeso molecolare:334.37Crenigacestat
CAS:Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.Formula:C22H23F3N4O4Purezza:97.27% - 98.99%Colore e forma:SolidPeso molecolare:464.442,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purezza:98.77%Colore e forma:SolidPeso molecolare:350.2PF-670462
CAS:PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.Formula:C19H22Cl2FN5Purezza:99.42% - 99.72%Colore e forma:SolidPeso molecolare:410.32Avagacestat
CAS:<p>Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,</p>Formula:C20H17ClF4N4O4SPurezza:98.87% - 99.73%Colore e forma:SolidPeso molecolare:520.89SH-4-54
CAS:SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.Formula:C29H27F5N2O5SPurezza:98% - 99.12%Colore e forma:SolidPeso molecolare:610.59ROCK-IN-2
CAS:ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.Formula:C18H13ClF2N6OPurezza:97.29%Colore e forma:SolidPeso molecolare:402.79GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Formula:C16H11N5O2SPurezza:98.86%Colore e forma:SolidPeso molecolare:337.36Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purezza:98.01% - 99.18%Colore e forma:SolidPeso molecolare:588.74IWP-O1
CAS:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Formula:C26H20N6OPurezza:99.12%Colore e forma:SolidPeso molecolare:432.48SAR407899
CAS:<p>SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.</p>Formula:C14H16N2O2Purezza:99.42%Colore e forma:SolidPeso molecolare:244.29BIO-013077-01
CAS:BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.Formula:C17H13N5Purezza:99.87%Colore e forma:SolidPeso molecolare:287.32Hydroxyfasudil Hydrochloride
CAS:Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Formula:C14H18ClN3O3SPurezza:98.05%Colore e forma:SolidPeso molecolare:343.83IQ 1
CAS:<p>IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.</p>Formula:C21H22N4O2Purezza:98.57% - ≥95%Colore e forma:SolidPeso molecolare:362.42AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Formula:C21H23N7O3SPurezza:98% - 99.25%Colore e forma:SolidPeso molecolare:453.52Lats-IN-1
CAS:Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.Formula:C18H14N4OSPurezza:97.54% - 99.79%Colore e forma:SolidPeso molecolare:334.39
