Recettore del fattore di crescita dei fibroblasti (FGFR)
Gli inibitori dei recettori del fattore di crescita dei fibroblasti (FGFR) sono terapie mirate che bloccano l'attività dei FGFR, coinvolti nella proliferazione cellulare, differenziazione e angiogenesi. La segnalazione FGFR contribuisce alla formazione di nuovi vasi sanguigni nei tumori, promuovendo la loro crescita e sopravvivenza. Inibire i FGFR può quindi ridurre l'angiogenesi e la progressione del tumore. Presso CymitQuimica, offriamo una gamma di inibitori FGFR di alta qualità per supportare la tua ricerca in oncologia, biologia dello sviluppo e angiogenesi.
Trovati 183 prodotti per "Recettore del fattore di crescita dei fibroblasti (FGFR)".
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FGFR1/DDR2 inhibitor 1
CAS:FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108Formula:C28H22F3N5OPurezza:99.43%Colore e forma:White SolidPeso molecolare:501.5Ref: TM-T11279
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg334,00€25mg550,00€50mg760,00€100mg1.108,00€Lucitanib
CAS:Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Formula:C26H25N3O4Purezza:96.13%Colore e forma:SolidPeso molecolare:443.49Ref: TM-T15185
1mg46,00€2mg59,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg255,00€50mg462,00€100mg672,00€2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Formula:C21H15ClF4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:482.8154Ref: IN-DA00ICN3
100gPrezzo su richiesta10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€1g131,00€5g255,00€50g617,00€10g619,00€Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurezza:98.78% - 99.85%Colore e forma:SolidPeso molecolare:437.52Aprutumab
CAS:Aprutumab, a human FGFR2 monoclonal antibody, targets FGFR2-IIIB/C and is used in antibody-drug conjugates.Purezza:98.69% (SEC-HPLC) - 98.69% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:150 kDaAmlexanox
CAS:Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.Formula:C16H14N2O4Purezza:99.67% - ≥95%Colore e forma:SolidPeso molecolare:298.29Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Formula:C21H19ClN4O4Purezza:98.46% - 99.96%Colore e forma:White SolidPeso molecolare:426.85Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
CAS:Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist.Formula:C26H32N4O8Purezza:99.83% - >99.99%Colore e forma:SolidPeso molecolare:528.55Gunagratinib
CAS:Gunagratinib (ICP-192) is a pan-FGFR inhibitor, useful in research on FGFR-related diseases.Formula:C22H25N5O4Purezza:99.68%Colore e forma:SolidPeso molecolare:423.47Ref: TM-T39682
1mg69,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€Triamcinolone acetonide
CAS:Triamcinolone acetonide (Azmacort) is a Corticosteroid.Formula:C24H31FO6Purezza:99.61% - 99.91%Colore e forma:SolidPeso molecolare:434.50Formononetin
CAS:Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.Formula:C16H12O4Purezza:97.39% - 99.94%Colore e forma:SolidPeso molecolare:268.26Ferulic Acid
CAS:Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.Formula:C10H10O4Purezza:99.72%Colore e forma:SolidPeso molecolare:194.18LC-MB12
CAS:LC-MB12 is a PROTAC FGFR2 compound that degrades FGFR2 and can be used to study gastric cancer.Formula:C43H44Cl2N10O8Purezza:99.16%Colore e forma:SolidPeso molecolare:899.78Pemigatinib
CAS:Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).Formula:C24H27F2N5O4Purezza:99.57% - 99.95%Colore e forma:White SolidPeso molecolare:487.52,5-Dihydroxybenzoic acid
CAS:2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity.Formula:C7H6O4Purezza:99.63%Colore e forma:White SolidPeso molecolare:154.12bFGF (119-126)
CAS:bFGF (119-126) is a biologically active peptide corresponding to the residues of human, bovine (119-126), mouse, rat (118-125), and Heparin-Binding GrowthFormula:C44H76N14O12Colore e forma:SolidPeso molecolare:993.16FGFR1/VEGFR2-IN-1
FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].Formula:C26H27N4O6PPurezza:98%Colore e forma:SolidPeso molecolare:522.49E7090
CAS:E-7090 is a fibroblast growth factor receptor inhibitor. E-7090 is a selective inhibitor of the tyrosine kinase activities of FGFR1, -2, and -3.Formula:C32H37N5O6Colore e forma:SolidPeso molecolare:587.67IMC-D11
IMC-D11 is a fully human anti-FGFR3 mAb that inhibits tumor cell proliferation by blocking ligand binding and receptor phosphorylation.Colore e forma:Odour Liquid
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