Recettore del fattore di crescita dei fibroblasti (FGFR)
Gli inibitori dei recettori del fattore di crescita dei fibroblasti (FGFR) sono terapie mirate che bloccano l'attività dei FGFR, coinvolti nella proliferazione cellulare, differenziazione e angiogenesi. La segnalazione FGFR contribuisce alla formazione di nuovi vasi sanguigni nei tumori, promuovendo la loro crescita e sopravvivenza. Inibire i FGFR può quindi ridurre l'angiogenesi e la progressione del tumore. Presso CymitQuimica, offriamo una gamma di inibitori FGFR di alta qualità per supportare la tua ricerca in oncologia, biologia dello sviluppo e angiogenesi.
Trovati 183 prodotti di "Recettore del fattore di crescita dei fibroblasti (FGFR)"
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FGFR2-IN-3 hydrochloride
CAS:FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.Formula:C28H25ClFN7O2Colore e forma:SolidPeso molecolare:546.0FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purezza:97.63% - 98.92%Colore e forma:SolidPeso molecolare:691.61PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Formula:C26H30Cl2N6O4Purezza:98.65%Colore e forma:SolidPeso molecolare:561.46Ref: TM-TQ0015
1mg81,00€2mg105,00€5mg170,00€10mg305,00€25mg520,00€50mg748,00€100mg1.026,00€1mL*10mM (DMSO)212,00€Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purezza:99.82%Colore e forma:SolidPeso molecolare:482.51SU4984
CAS:SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).Formula:C20H19N3O2Purezza:97.20%Colore e forma:SolidPeso molecolare:333.38PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48Futibatinib
CAS:Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.Formula:C22H22N6O3Purezza:97.66% - 99.44%Colore e forma:SolidPeso molecolare:418.45Ref: TM-T5044
1mg52,00€5mg120,00€10mg170,00€25mg329,00€50mg512,00€100mg662,00€200mg939,00€1mL*10mM (DMSO)134,00€ASP5878
CAS:ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.Formula:C18H19F2N5O4Purezza:99.8% - 99.89%Colore e forma:SolidPeso molecolare:407.37SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purezza:98.91% - 99.64%Colore e forma:Yellow-Green SolidPeso molecolare:296.32FIIN-2
CAS:FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.Formula:C35H38N8O4Purezza:97.82% - 99.65%Colore e forma:Crystalline SolidPeso molecolare:634.73GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurezza:99.87%Colore e forma:SolidPeso molecolare:473.98Ref: TM-T6930
10mg44,00€25mg70,00€50mg96,00€100mg140,00€200mg229,00€500mg329,00€1mL*10mM (DMSO)34,00€Ferulic acid sodium
CAS:Ferulic acid sodium (Sodium ferulic) is an agent used in the treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.Formula:C10H9NaO4Purezza:99.58%Colore e forma:White Crystalline PowderPeso molecolare:216.16Roblitinib
CAS:Roblitinib (FGF-401), an FGFR4 inhibitor, potentially blocks tumor growth by halting cell proliferation and survival.Formula:C25H30N8O4Purezza:97.27% - 99%Colore e forma:SolidPeso molecolare:506.56LY2874455
CAS:LY2874455 has been used in trials studying the treatment of Advanced Cancer.Formula:C21H19Cl2N5O2Purezza:97.22% - 99.46%Colore e forma:SolidPeso molecolare:444.31Ref: TM-T2361
1mg49,00€5mg97,00€10mg154,00€25mg298,00€50mg472,00€100mg707,00€200mg938,00€1mL*10mM (DMSO)106,00€PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurezza:99.13% - 99.83%Colore e forma:SolidPeso molecolare:369.22Ref: TM-T6932
1mg39,00€2mg49,00€5mg66,00€10mg89,00€25mg155,00€50mg222,00€100mg310,00€1mL*10mM (DMSO)56,00€EOC317
CAS:EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).Formula:C27H26F5N7O3Purezza:98.00% - 99.26%Colore e forma:SolidPeso molecolare:591.53Derazantinib
CAS:Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C29H29FN4OPurezza:99.71%Colore e forma:SolidPeso molecolare:468.57Ref: TM-TQ0228
1mg52,00€5mg116,00€10mg169,00€25mg271,00€50mg401,00€100mg597,00€200mg850,00€1mL*10mM (DMSO)125,00€Zoligratinib
CAS:Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.Formula:C20H16N6OPurezza:95.28% - 99.51%Colore e forma:SolidPeso molecolare:356.38KHS 101
CAS:<p>KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.</p>Formula:C18H21N5SPurezza:99.63%Colore e forma:SolidPeso molecolare:339.46Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurezza:99.43% - 99.98%Colore e forma:SolidPeso molecolare:649.76
