CymitQuimica logo
Recettore del fattore di crescita dei fibroblasti (FGFR)

Recettore del fattore di crescita dei fibroblasti (FGFR)

Gli inibitori dei recettori del fattore di crescita dei fibroblasti (FGFR) sono terapie mirate che bloccano l'attività dei FGFR, coinvolti nella proliferazione cellulare, differenziazione e angiogenesi. La segnalazione FGFR contribuisce alla formazione di nuovi vasi sanguigni nei tumori, promuovendo la loro crescita e sopravvivenza. Inibire i FGFR può quindi ridurre l'angiogenesi e la progressione del tumore. Presso CymitQuimica, offriamo una gamma di inibitori FGFR di alta qualità per supportare la tua ricerca in oncologia, biologia dello sviluppo e angiogenesi.

Trovati 169 prodotti di "Recettore del fattore di crescita dei fibroblasti (FGFR)"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • ARQ 069
    Targetmol
    + Info

    ARQ 069

    CAS:
    <p>ARQ 069 inhibits FGFR2 phosphorylation concentration-dependently (IC50: 9.7 µM), without affecting β-actin. Preferentially binds inactive FGFR1/2.</p>
    Formula:C18H15N3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:273.33

    Ref: TM-T10372

  • FGFR2-IN-1
    Targetmol
    + Info

    FGFR2-IN-1

    CAS:
    <p>FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used to study FGFR2-associated cancers.</p>
    Formula:C22H19N3O2
    Purezza:98.71%
    Colore e forma:Solid
    Peso molecolare:357.41

    Ref: TM-T61304

  • FIIN-4
    Targetmol
    + Info

    FIIN-4

    CAS:
    <p>FIIN-4 is a covalent inhibitor of FGFR and can be used in studies about metastatic breast cancer.</p>
    Formula:C35H38N8O4
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:634.73

    Ref: TM-T27319

  • FGFR3-IN-5
    Targetmol
    + Info

    FGFR3-IN-5

    CAS:
    <p>FGFR3-IN-5: potent, selective FGFR3 inhibitor. IC50: 3 nM FGFR3, 44 nM FGFR2, 289 nM FGFR1. For cancer research.</p>
    Formula:C24H24FN7O3
    Colore e forma:Solid
    Peso molecolare:477.49

    Ref: TM-T73146

  • CPL304110
    Targetmol
    + Info

    CPL304110

    CAS:
    <p>CPL304110: oral, selective FGFR 1-3 inhibitor; IC50 - FGFR1: 0.75nM, FGFR2: 0.5nM, FGFR3: 3.05nM.</p>
    Formula:C25H30N6O2
    Colore e forma:Solid
    Peso molecolare:446.54

    Ref: TM-T62652

  • CAY10583
    Targetmol
    + Info

    CAY10583

    CAS:
    <p>CAY10583 is a selective BLT2 agonist that increases TGF-β1 and bFGF, promotes keratinocyte migration, accelerates wound healing in diabetic mice.</p>
    Formula:C25H25NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:387.47

    Ref: TM-T26958

  • MAX-40279 hemiadipate
    Targetmol
    + Info

    MAX-40279 hemiadipate

    CAS:
    <p>MAX-40279 hemiadipate: Potent FLT3/FGFR inhibitor; potential in AML treatment. (Patent WO2021180032A1)</p>
    Formula:C50H56F2N12O6S2
    Colore e forma:Solid
    Peso molecolare:1023.19

    Ref: TM-T64129

  • TG 100801 Hydrochloride
    Targetmol
    + Info

    TG 100801 Hydrochloride

    CAS:
    <p>TG 100801: prodrug for macular degeneration. TG 100572: inhibits kinases (VEGFRs, FGFRs, PDGFRβ, Src family), with varying IC50s.</p>
    Formula:C33H31Cl2N5O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:616.54

    Ref: TM-T13157L

  • TG 100572
    Targetmol
    + Info

    TG 100572

    CAS:
    <p>TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2</p>
    Formula:C26H26ClN5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:475.97

    Ref: TM-T13156

  • Infigratinib phosphate
    Targetmol
    + Info

    Infigratinib phosphate

    CAS:
    <p>Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and</p>
    Formula:C26H34Cl2N7O7P
    Purezza:99.24% - 99.6%
    Colore e forma:Solid
    Peso molecolare:658.47

    Ref: TM-T16364

  • FGFR2-IN-2
    Targetmol
    + Info

    FGFR2-IN-2

    CAS:
    <p>FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.</p>
    Formula:C23H22N4O
    Purezza:98.09%
    Colore e forma:Solid
    Peso molecolare:370.45

    Ref: TM-T61473

  • MAX-40279 hemifumarate
    Targetmol
    + Info

    MAX-40279 hemifumarate

    CAS:
    <p>MAX-40279 hemifumarate inhibits FLT3 and FGFR kinases, showing promise for AML treatment.</p>
    Formula:C48H50F2N12O6S2
    Colore e forma:Solid
    Peso molecolare:993.12

    Ref: TM-T63916

  • PP58
    Targetmol
    + Info

    PP58

    CAS:
    <p>PP58 is an inhibitor of PDGFR, FGFR and Src family.</p>
    Formula:C22H19Cl2N5O2
    Purezza:99.21%
    Colore e forma:Solid
    Peso molecolare:456.32

    Ref: TM-T13824

  • FGFR-IN-4
    Targetmol
    + Info

    FGFR-IN-4

    CAS:
    <p>FGFR-IN-4 is a potent inhibitor of FGFR. FGFR-IN-4 has potential for cancer disease studies.</p>
    Formula:C24H21N7O2
    Colore e forma:Solid
    Peso molecolare:439.47

    Ref: TM-T62522

  • TYRA-300
    Targetmol
    + Info

    TYRA-300

    CAS:
    <p>TYRA-300 is an oral and selective FGFR3 inhibito, in the Ba/F3 cell line for the treatment of metastatic uroepithelial carcinomas (mUCs) and chondrodysplasia.</p>
    Formula:C25H24Cl2N6O3S
    Purezza:99.66%
    Colore e forma:Solid
    Peso molecolare:559.47

    Ref: TM-T88841

  • TG 100572 Hydrochloride
    Targetmol
    + Info

    TG 100572 Hydrochloride

    CAS:
    <p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>
    Formula:C26H27Cl2N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:512.43

    Ref: TM-T13156L

  • Sulfatinib
    Targetmol
    + Info

    Sulfatinib

    CAS:
    <p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>
    Formula:C24H28N6O3S
    Purezza:99.21% - >99.99%
    Colore e forma:Solid
    Peso molecolare:480.58

    Ref: TM-T4075

  • FGFR-IN-2
    Targetmol
    + Info

    FGFR-IN-2

    CAS:
    <p>FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).</p>
    Formula:C25H30N6O2
    Colore e forma:Solid
    Peso molecolare:446.54

    Ref: TM-T62653

  • Logo CymitQuimica
    Targetmol
    + Info

    SNIPER(TACC3)-11

    CAS:
    <p>SNIPER(TACC3)-11 is a powerful FGFR3-TACC3 protein degrader, reducing its amount and hindering FGFR3-TACC3+ cancer cell growth.</p>
    Formula:C51H66N10O7S2
    Colore e forma:Solid
    Peso molecolare:995.26

    Ref: TM-T74462

  • Logo CymitQuimica
    Targetmol
    + Info

    CP-547632 TFA

    CAS:
    <p>CP-547632 TFA, an oral VEGFR-2 and FGF inhibitor, IC50: VEGFR-2 at 11 nM, FGF at 9 nM, shows antitumor activity.</p>
    Formula:C22H25BrF5N5O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:646.43

    Ref: TM-T74000