VEGFR
Gli inibitori del recettore del fattore di crescita endoteliale vascolare (VEGFR) sono composti che bloccano la segnalazione del VEGFR, un recettore chiave nella via VEGF, cruciale per l'angiogenesi. Gli inibitori del VEGFR impediscono la formazione di nuovi vasi sanguigni che forniscono nutrienti e ossigeno ai tumori, inibendo così la crescita tumorale. Questi inibitori sono ampiamente utilizzati nella terapia e nella ricerca sul cancro per studiare i meccanismi dell'angiogenesi e sviluppare trattamenti anticancro. Presso CymitQuimica, offriamo una gamma completa di inibitori del VEGFR di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 239 prodotti di "VEGFR"
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JK-P3
CAS:Formula:C18H17N3O3Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:323.35Nintedanib
CAS:Formula:C31H33N5O4Purezza:>95.0%(T)(HPLC)Colore e forma:White to Yellow to Yellow green powder to crystalPeso molecolare:539.64Sunitinib Malate
CAS:Formula:C22H27FN4O2·C4H6O5Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:532.57Cediranib
CAS:Formula:C25H27FN4O3Purezza:>95.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:450.51Pazopanib
CAS:Formula:C21H23N7O2SPurezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:437.52Linifanib
CAS:Formula:C21H18FN5OPurezza:>95.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:375.41Pazopanib Hydrochloride
CAS:Formula:C21H23N7O2S·HClPurezza:>95.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:473.98SU5408
CAS:SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.Formula:C18H18N2O3Purezza:99.35%Colore e forma:SolidPeso molecolare:310.35Ref: TM-T4026
1mg70,00€5mg187,00€10mg283,00€25mg518,00€50mg700,00€100mg905,00€500mg1.786,00€1mL*10mM (DMSO)207,00€Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:482.82Ref: TM-T1792
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)57,00€JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purezza:97.08%Colore e forma:SolidPeso molecolare:364.79Ref: TM-T22349
1mg38,00€5mg78,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€1mL*10mM (DMSO)84,00€VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formula:C19H24N8Purezza:99.92%Colore e forma:SolidPeso molecolare:364.45Ref: TM-T2056
1mg96,00€5mg235,00€10mg350,00€25mg590,00€50mg840,00€100mg1.130,00€1mL*10mM (DMSO)235,00€BMS-794833
CAS:BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.Formula:C23H15ClF2N4O3Purezza:98% - 99.69%Colore e forma:SolidPeso molecolare:468.84Gandotinib
CAS:LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formula:C23H25ClFN7OPurezza:99.33% - 99.86%Colore e forma:SolidPeso molecolare:469.94ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.
Formula:C19H16BrFN6O2Purezza:99.12%Colore e forma:SolidPeso molecolare:459.27SKLB1002
CAS:SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.Formula:C13H12N4O2S2Purezza:98.51% - >99.99%Colore e forma:SolidPeso molecolare:320.39Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurezza:99.03% - 99.79%Colore e forma:SolidPeso molecolare:522.96PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purezza:97.58% - 99.94%Colore e forma:SolidPeso molecolare:419.48OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:443.44Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purezza:99.69%Colore e forma:SolidPeso molecolare:500.83Ref: TM-T1792L
5mg35,00€10mg48,00€25mg69,00€50mg88,00€100mg140,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)58,00€VEGFR2-IN-2
CAS:VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Formula:C15H11BrN2OPurezza:99.504%Colore e forma:SolidPeso molecolare:315.16Ref: TM-T9724
1mg35,00€5mg73,00€10mg105,00€25mg195,00€50mg311,00€100mg445,00€200mg617,00€1mL*10mM (DMSO)93,00€Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)202,00€XL092
CAS:XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
Formula:C29H25FN4O5Purezza:98.60%Colore e forma:SolidPeso molecolare:528.53(Z)-Guggulsterone
CAS:(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formula:C21H28O2Purezza:98.93% - 99.72%Colore e forma:SolidPeso molecolare:312.45Tanshinone IIA
CAS:Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.Formula:C19H18O3Purezza:99.04% - >99.99%Colore e forma:Cherry CrystalPeso molecolare:294.34Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purezza:99.82%Colore e forma:SolidPeso molecolare:482.51Takeda-6d
CAS:Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formula:C27H19ClFN5O3SPurezza:98.27%Colore e forma:SolidPeso molecolare:547.99Ref: TM-T22436
1mg92,00€2mg128,00€5mg178,00€10mg268,00€25mg439,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)243,00€Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purezza:99.7% - >99.99%Colore e forma:White SolidPeso molecolare:475.35Ref: TM-T1656
10mg50,00€25mg65,00€50mg92,00€100mg166,00€200mg224,00€500mg359,00€1mL*10mM (DMSO)52,00€PD173074
CAS:PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formula:C28H41N7O3Purezza:98.15% - 98.21%Colore e forma:Yellow SolidPeso molecolare:523.67Ref: TM-T2642
5mg40,00€10mg54,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€1mL*10mM (DMSO)56,00€TAK-593
CAS:TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).Formula:C23H23N7O3Purezza:99.37%Colore e forma:SolidPeso molecolare:445.47Ref: TM-T16975
2mg42,00€5mg62,00€10mg96,00€25mg182,00€50mg284,00€100mg409,00€200mg575,00€1mL*10mM (DMSO)73,00€Bevacizumab
CAS:Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Purezza:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Colore e forma:LiquidPeso molecolare:146.53 kDaRef: TM-T9904
1mg127,00€2mg202,00€5mg376,00€10mg560,00€25mg895,00€50mg1.216,00€100mg1.634,00€200mg2.213,00€Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purezza:98.76%Colore e forma:SolidPeso molecolare:244.29PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purezza:98.45% - 99.93%Colore e forma:SolidPeso molecolare:319.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.
Formula:C17H16N2OPurezza:>99.99%Colore e forma:SolidPeso molecolare:264.32Semaxinib
CAS:Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.
Formula:C15H14N2OPurezza:99.84%Colore e forma:Yellow To Yellow OrangePeso molecolare:238.28ZM 306416
CAS:ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
Formula:C16H13ClFN3O2Purezza:99.37% - ≥95%Colore e forma:SolidPeso molecolare:333.74Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purezza:99.52%Colore e forma:SolidPeso molecolare:346.81Sodium taurocholate
CAS:Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.Formula:C26H44NO7S·NaPurezza:95% - 99.64%Colore e forma:White PowderPeso molecolare:537.69Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purezza:97.61% - >99.99%Colore e forma:SolidPeso molecolare:570.64Ref: TM-T3211
1mg49,00€5mg84,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€1mL*10mM (DMSO)90,00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purezza:98.13%Colore e forma:SolidPeso molecolare:442.48MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Formula:C26H20FN5O2S2Purezza:98.06% - 98.68%Colore e forma:SolidPeso molecolare:517.6Ref: TM-T6351
2mg35,00€5mg52,00€10mg85,00€25mg164,00€50mg255,00€100mgPrezzo su richiesta1mL*10mM (DMSO)62,00€R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Formula:C18H14ClFN4OPurezza:98.422%Colore e forma:SolidPeso molecolare:356.78Ref: TM-TQ0317
1mg39,00€2mg52,00€5mg84,00€10mg130,00€25mg264,00€50mg423,00€100mg640,00€1mL*10mM (DMSO)93,00€SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formula:C18H22N4O4Purezza:99.74%Colore e forma:SolidPeso molecolare:358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€1mL*10mM (DMSO)79,00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurezza:99.43% - 99.98%Colore e forma:SolidPeso molecolare:649.76Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurezza:98.97% - 99.88%Colore e forma:SolidPeso molecolare:480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormula:C18H22N2OPurezza:98.21% - 99.87%Colore e forma:Yellow SolidPeso molecolare:282.38Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Formula:C20H16ClN5O3Purezza:97.61% - 99.81%Colore e forma:SolidPeso molecolare:409.83Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Formula:C26H21F3N4O4Purezza:99.67% - 99.75%Colore e forma:SolidPeso molecolare:510.46Gamabufotalin
CAS:Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.Formula:C24H34O5Purezza:99.18% - 99.51%Colore e forma:SolidPeso molecolare:402.52WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purezza:99.21%Colore e forma:SolidPeso molecolare:297.31SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purezza:98.91% - 99.64%Colore e forma:Yellow-Green SolidPeso molecolare:296.32
