VEGFR
Gli inibitori del recettore del fattore di crescita endoteliale vascolare (VEGFR) sono composti che bloccano la segnalazione del VEGFR, un recettore chiave nella via VEGF, cruciale per l'angiogenesi. Gli inibitori del VEGFR impediscono la formazione di nuovi vasi sanguigni che forniscono nutrienti e ossigeno ai tumori, inibendo così la crescita tumorale. Questi inibitori sono ampiamente utilizzati nella terapia e nella ricerca sul cancro per studiare i meccanismi dell'angiogenesi e sviluppare trattamenti anticancro. Presso CymitQuimica, offriamo una gamma completa di inibitori del VEGFR di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 249 prodotti di "VEGFR"
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Oglufanide
CAS:<p>Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).</p>Formula:C16H19N3O5Purezza:99.80%Colore e forma:SolidPeso molecolare:333.34EOC317
CAS:EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).Formula:C27H26F5N7O3Purezza:98.00% - 99.26%Colore e forma:SolidPeso molecolare:591.53SU5208
CAS:SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).Formula:C13H9NOSPurezza:99.62%Colore e forma:SolidPeso molecolare:227.28Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurezza:98% - 98.24%Colore e forma:SolidPeso molecolare:375.4GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurezza:99.87%Colore e forma:SolidPeso molecolare:473.98KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formula:C24H18F3N3O4Purezza:99.22% - 99.9%Colore e forma:SolidPeso molecolare:469.41Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formula:C20H15ClN4·2HClPurezza:99.16%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:419.73Golvatinib
CAS:Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factorFormula:C33H37F2N7O4Purezza:98.24% - ≥95%Colore e forma:SolidPeso molecolare:633.69Ningetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurezza:99.93%Colore e forma:SolidPeso molecolare:728.79Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurezza:98% - 99.60%Colore e forma:SolidPeso molecolare:532.56SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Formula:C16H13NO2Purezza:99.45% - 99.55%Colore e forma:SolidPeso molecolare:251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formula:C19H25ClN8Purezza:99.52%Colore e forma:SolidPeso molecolare:400.91Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Formula:C22H28FN4O6PPurezza:98.56%Colore e forma:SolidPeso molecolare:494.45Ramucirumab
CAS:<p>Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.</p>Formula:C285H434N74O88S2Purezza:98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Colore e forma:LiquidPeso molecolare:143.77 kDaNingetinib
CAS:Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C31H29FN4O5Purezza:99.95% - 99.98%Colore e forma:SolidPeso molecolare:556.58Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Formula:C15H10O6Purezza:98% - 98%Colore e forma:SolidPeso molecolare:286.24XL 999
CAS:<p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>Formula:C26H28FN5OPurezza:98.24% - 99.55%Colore e forma:SolidPeso molecolare:445.53Cabozantinib
CAS:<p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>Formula:C28H24FN3O5Purezza:99.68% - 99.88%Colore e forma:SolidPeso molecolare:501.51BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purezza:97.71% - 99.89%Colore e forma:SolidPeso molecolare:439.39Su1498
CAS:<p>Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.</p>Formula:C25H30N2O2Purezza:99.54%Colore e forma:SolidPeso molecolare:390.52
