CymitQuimica logo
c-RET

c-RET

Gli inibitori di c-RET prendono di mira il proto-oncogene RET (Rearranged during Transfection), che codifica una tirosina chinasi recettoriale coinvolta nella crescita, differenziazione e sopravvivenza cellulare. L'attivazione anomala della segnalazione RET può portare a una proliferazione cellulare incontrollata e alla resistenza all'apoptosi, contribuendo allo sviluppo di tumori come il carcinoma midollare della tiroide e il carcinoma polmonare non a piccole cellule. L'inibizione di c-RET può indurre l'apoptosi nelle cellule tumorali ed è un approccio promettente nella terapia oncologica mirata. Presso CymitQuimica, offriamo una varietà di inibitori di c-RET di alta qualità per supportare la tua ricerca in oncologia, trasduzione del segnale e apoptosi.

Trovati 51 prodotti di "c-RET"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • Selpercatinib
    Targetmol
    + Info

    Selpercatinib

    CAS:
    <p>"Selpercatinib (LOXO-292) is a RET tyrosine kinase inhibitor with IC50s of 14.0, 24.1, 530.7 nM for different RET mutations."</p>
    Formula:C29H31N7O3
    Purezza:99.89% - >99.99%
    Colore e forma:Solid
    Peso molecolare:525.6

    Ref: TM-T8222

  • Pyrazoloadenine
    Targetmol
    + Info

    Pyrazoloadenine

    CAS:
    <p>Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.</p>
    Formula:C5H5N5
    Purezza:99.02%
    Colore e forma:Beige Powder
    Peso molecolare:135.13

    Ref: TM-T9366

  • BBT594
    Targetmol
    + Info

    BBT594

    CAS:
    <p>BBT594 (NVP-BBT594)(NVP-BBT594) is a potent inhibitor of receptor tyrosine kinase RET,Treatment of cancer.</p>
    Formula:C28H30F3N7O3
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:569.58

    Ref: TM-T7418

  • SPP-86
    Targetmol
    + Info

    SPP-86

    CAS:
    <p>SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.</p>
    Formula:C16H15N5
    Purezza:99.53%
    Colore e forma:Solid
    Peso molecolare:277.32

    Ref: TM-T16923

  • RET V804M-IN-1
    Targetmol
    + Info

    RET V804M-IN-1

    CAS:
    <p>RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).</p>
    Formula:C19H16N6O
    Purezza:97.94% - 99.62%
    Colore e forma:Solid
    Peso molecolare:344.37

    Ref: TM-T8467

  • WHI-P180 hydrochloride
    Targetmol
    + Info

    WHI-P180 hydrochloride

    CAS:
    <p>WHI-P180 (Janex 3) inhibits RET, KDR and EGFR with IC50 values of 5 nM, 66 nM and 4 μM, respectively. WHI-P180 is a multi-kinase inhibitor.</p>
    Formula:C16H16ClN3O3
    Colore e forma:Solid
    Peso molecolare:333.77

    Ref: TM-T61007

  • RET-IN-22
    Targetmol
    + Info

    RET-IN-22

    CAS:
    <p>RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-</p>
    Formula:C29H31F3N6O4
    Colore e forma:Solid
    Peso molecolare:584.59

    Ref: TM-T78683

  • RET-IN-15
    Targetmol
    + Info

    RET-IN-15

    CAS:
    <p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>
    Formula:C27H28N8O2
    Colore e forma:Solid
    Peso molecolare:496.56

    Ref: TM-T63358

  • RET-IN-6
    Targetmol
    + Info

    RET-IN-6

    CAS:
    <p>RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).</p>
    Formula:C30H29N7
    Colore e forma:Solid
    Peso molecolare:487.6

    Ref: TM-T63249

  • DUN73423
    Targetmol
    + Info

    DUN73423

    CAS:
    <p>DUN73423 (RET-IN-21) is a potent tyrosine kinase (RET) inhibitor with antitumour activity for the study of cancer.</p>
    Formula:C19H16N6O
    Purezza:98.09%
    Colore e forma:Solid
    Peso molecolare:344.37

    Ref: TM-T69644

  • RET-IN-8
    Targetmol
    + Info

    RET-IN-8

    CAS:
    <p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>
    Formula:C27H30N6O3
    Colore e forma:Solid
    Peso molecolare:486.57

    Ref: TM-T63230

  • TRK II-IN-1
    Targetmol
    + Info

    TRK II-IN-1

    CAS:
    <p>TRK II-IN-1: potent type II TRK inhibitor; IC50s: TRKA (3.3 nM), TRKB (6.4 nM), TRKC (4.3 nM), TRKA G667C (9.4 nM); also targets FLT3, RET, VEGFR2.</p>
    Formula:C29H31F3N8O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:564.6

    Ref: TM-T73033

  • RET-IN-16
    Targetmol
    + Info

    RET-IN-16

    CAS:
    <p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>
    Formula:C31H29F3N8O2
    Colore e forma:Solid
    Peso molecolare:602.61

    Ref: TM-T73256

  • RET-IN-12
    Targetmol
    + Info

    RET-IN-12

    CAS:
    <p>RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).</p>
    Formula:C30H30F3N5O4
    Colore e forma:Solid
    Peso molecolare:581.59

    Ref: TM-T64103

  • RET-IN-23
    Targetmol
    + Info

    RET-IN-23

    CAS:
    <p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>
    Formula:C28H28FN11
    Purezza:97.46%
    Colore e forma:Solid
    Peso molecolare:537.59

    Ref: TM-T79099

  • RET-IN-3
    Targetmol
    + Info

    RET-IN-3

    CAS:
    <p>RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.</p>
    Formula:C18H21N5O2
    Purezza:99.52%
    Colore e forma:Solid
    Peso molecolare:339.39

    Ref: TM-T9673

  • RET-IN-25
    Targetmol
    + Info

    RET-IN-25

    CAS:
    <p>RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximal</p>
    Formula:C22H17N3O5S
    Colore e forma:Solid
    Peso molecolare:435.45

    Ref: TM-T79726

  • RET-IN-17
    Targetmol
    + Info

    RET-IN-17

    CAS:
    <p>RET-IN-17 inhibits RET kinase; may help in IBS pain and RET-activated cancers.</p>
    Formula:C27H28F4N4O4
    Colore e forma:Solid
    Peso molecolare:548.53

    Ref: TM-T63877

  • Vepafestinib
    Targetmol
    + Info

    Vepafestinib

    CAS:
    <p>Vepafestinib is a RET inhibitor with potential antineoplastic activity[1].</p>
    Formula:C26H30N6O3
    Purezza:98.56%
    Colore e forma:Solid
    Peso molecolare:474.55

    Ref: TM-T9445

  • RET-IN-24
    Targetmol
    + Info

    RET-IN-24

    CAS:
    <p>RET-IN-24 (Compound 26) is a selective inhibitor of RET tyrosine kinase, demonstrating antitumor activity [1].</p>
    Formula:C27H26F2N8O
    Colore e forma:Solid
    Peso molecolare:516.55

    Ref: TM-T79163