FLT
Gli inibitori della FLT (Fms-like tyrosine kinase) sono composti che prendono di mira i recettori FLT, coinvolti nella regolazione dell'angiogenesi attraverso la via del VEGF (fattore di crescita endoteliale vascolare). I recettori FLT svolgono un ruolo cruciale nello sviluppo di nuovi vasi sanguigni nei tumori. Inibendo i recettori FLT, è possibile ridurre efficacemente l'angiogenesi e la crescita tumorale, rendendo questi inibitori importanti nella terapia del cancro. Presso CymitQuimica, offriamo una selezione di inibitori della FLT di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 86 prodotti per "FLT".
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INE963
CAS:INE963: Potent against Pf 3D7 (EC50=6nM), clears parasites in <24h; effective on P. falciparum/vivax isolates (EC50=0.01-7nM).Formula:C19H26N6O2SPurezza:99.08% - 99.45%Colore e forma:SolidPeso molecolare:402.51Ref: TM-T9741
10mgPrezzo su richiesta25mgPrezzo su richiesta1mg59,00€5mg128,00€1mL*10mM (DMSO)142,00€FLT3-IN-2
CAS:FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Formula:C21H16ClF3N4Purezza:97.57% - 98.53%Colore e forma:SolidPeso molecolare:416.83Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurezza:96.13% - 99.09%Colore e forma:White SolidPeso molecolare:624.42Ref: TM-T2605
1mg44,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg117,00€25mg210,00€50mg354,00€100mg530,00€500mg1.153,00€TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurezza:99.28% - 99.82%Colore e forma:SolidPeso molecolare:380.85TCS 359
CAS:TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.Formula:C18H20N2O4SPurezza:99.31%Colore e forma:SolidPeso molecolare:360.427Adezkibart
CAS:Adezkibart is a human-derived monoclonal antibody immunosuppressant that targets the human FMS-like tyrosine kinase 3 ligand (FLT3LG). It was discovered in the Chinese hamster ovary cell line CHO-K1. Adezkibart binds to FLT3LG, blocking the associated signaling pathways to suppress immune responses, thereby exerting an immunosuppressive effect. It holds potential for research in immune-related diseases.Emirodatamab
CAS:Emirodatamab (AMG-427) is an anti-FLT3/CD3 bispecific T-cell engager with an extended half-life. It can induce high cytotoxicity in primary AML progenitor cells and enhance FLT-3 expression. Combining Emirodatamab with anti-PD-1 antibodies increases T-cell dependent cytotoxicity (TDCC). This compound is under investigation for use in relapsed or refractory AML.Colore e forma:LiquidFLT3-IN-15
CAS:FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50: 0.32 nM).Formula:C22H23ClFN5O2Colore e forma:SolidPeso molecolare:443.91FLT3/ITD-IN-2
CAS:FLT3/ITD-IN-2: Powerful FLT3/ITD, FLT3D835Y, and FLT3 inhibitor; hinders AML cell growth. IC50s: 0.3-1.0 nM.Formula:C23H26F3N7O2Colore e forma:SolidPeso molecolare:489.49FLT3-IN-6
CAS:FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.Formula:C23H25N5O3Colore e forma:SolidPeso molecolare:419.48AAE871
CAS:AAE871 is a type I FLT3 inhibitor.Formula:C24H34N8O2SColore e forma:SolidPeso molecolare:498.64LBW242
CAS:LBW242: oral 3-mer Smac mimetic, IAP inhibitor, targets multiple myeloma, enhances TRAIL/chemo death in ovarian cancer, active on mutant FLT3 cells.Formula:C27H42N4O2Purezza:98%Colore e forma:SolidPeso molecolare:454.65FLT3/ITD-IN-3
CAS:FLT3/ITD-IN-3 (Compound 19) is a potent FLT3-ITD inhibitor with IC50 values: FLT3D835Y (0.3 nM), FLT3 (0.4 nM), inhibits AML cell proliferation.Formula:C22H26ClN7O2Colore e forma:SolidPeso molecolare:455.94KRN383
CAS:KRN383 inhibits ITD cell growth at ≤2.9 nM, erases ITD tumors in mice at 80 mg/kg dose, and may suit various treatment plans.Formula:C17H17N3O4Colore e forma:SolidPeso molecolare:327.33FLT3-IN-12
CAS:FLT3-IN-12: potent, selective oral FLT3 inhibitor; FLT3-WT IC50: 1.48 nM, FLT3-D835Y: 2.87 nM; >1000x selective over c-KIT; anti-AML, IC50: 0.75 nM MV4-11.Formula:C21H23F3N6OColore e forma:SolidPeso molecolare:432.44PDGFRα/FLT3-ITD-IN-2
CAS:PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM).Formula:C28H41N9OColore e forma:SolidPeso molecolare:519.68FLT3-IN-18
CAS:FLT3-IN-18: potent, selective FLT3 inhibitor, IC50 0.003 μM, induces apoptosis, G1 arrest, blocks FLT3/STAT5, potential in AML research.Formula:C26H36N8OColore e forma:SolidPeso molecolare:476.62FLT3/D835Y-IN-1
CAS:FLT3/D835Y-IN-1, an oral FLT3 inhibitor (IC50: FLT3 - 0.26 nM, D835Y - 0.18 nM), shows anticancer potential in AML research.Formula:C22H21N5O3Colore e forma:SolidPeso molecolare:403.43AGL 2043
CAS:AGL 2043 is a potent, reversible, ATP-competitive inhibitor of type III receptor tyrosine kinases.Formula:C15H12N4SColore e forma:SolidPeso molecolare:280.35MDK5466
CAS:MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death.Formula:C21H23N3OSPurezza:98%Colore e forma:SolidPeso molecolare:365.49
