FLT
Gli inibitori della FLT (Fms-like tyrosine kinase) sono composti che prendono di mira i recettori FLT, coinvolti nella regolazione dell'angiogenesi attraverso la via del VEGF (fattore di crescita endoteliale vascolare). I recettori FLT svolgono un ruolo cruciale nello sviluppo di nuovi vasi sanguigni nei tumori. Inibendo i recettori FLT, è possibile ridurre efficacemente l'angiogenesi e la crescita tumorale, rendendo questi inibitori importanti nella terapia del cancro. Presso CymitQuimica, offriamo una selezione di inibitori della FLT di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 88 prodotti di "FLT"
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5'-Fluoroindirubinoxime
CAS:<p>5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).</p>Formula:C16H10FN3O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:295.27TCS 359
CAS:TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.Formula:C18H20N2O4SPurezza:99.31%Colore e forma:SolidPeso molecolare:360.43UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.Formula:C28H42Cl2N6OPurezza:99.71%Colore e forma:SolidPeso molecolare:549.624SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Formula:C33H38N8O4SPurezza:96.4% - 99.67%Colore e forma:SolidPeso molecolare:642.77UNC2541
CAS:<p>UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.</p>Formula:C24H34FN7O2Purezza:98.33%Colore e forma:SolidPeso molecolare:471.57TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurezza:99.28% - 99.82%Colore e forma:SolidPeso molecolare:380.85FLT3-IN-2
CAS:<p>FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).</p>Formula:C21H16ClF3N4Purezza:97.57% - 98.53%Colore e forma:SolidPeso molecolare:416.83PDGFRα/FLT3-ITD-IN-2
CAS:PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM).Formula:C28H41N9OColore e forma:SolidPeso molecolare:519.68FLT3-IN-4
CAS:FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenousFormula:C23H25N7O2Purezza:99.9%Colore e forma:SolidPeso molecolare:431.49LBW242
CAS:LBW242: oral 3-mer Smac mimetic, IAP inhibitor, targets multiple myeloma, enhances TRAIL/chemo death in ovarian cancer, active on mutant FLT3 cells.Formula:C27H42N4O2Purezza:98%Colore e forma:SolidPeso molecolare:454.65FLT3/ITD-IN-3
CAS:<p>FLT3/ITD-IN-3 (Compound 19) is a potent FLT3-ITD inhibitor with IC50 values: FLT3D835Y (0.3 nM), FLT3 (0.4 nM), inhibits AML cell proliferation.</p>Formula:C22H26ClN7O2Colore e forma:SolidPeso molecolare:455.94KRN383
CAS:KRN383 inhibits ITD cell growth at ≤2.9 nM, erases ITD tumors in mice at 80 mg/kg dose, and may suit various treatment plans.Formula:C17H17N3O4Colore e forma:SolidPeso molecolare:327.33FN-1501
CAS:<p>FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).</p>Formula:C22H25N9OPurezza:97.4%Colore e forma:SolidPeso molecolare:431.49FLT3-IN-12
CAS:FLT3-IN-12: potent, selective oral FLT3 inhibitor; FLT3-WT IC50: 1.48 nM, FLT3-D835Y: 2.87 nM; >1000x selective over c-KIT; anti-AML, IC50: 0.75 nM MV4-11.Formula:C21H23F3N6OColore e forma:SolidPeso molecolare:432.44FLT3-IN-15
CAS:FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50: 0.32 nM).Formula:C22H23ClFN5O2Colore e forma:SolidPeso molecolare:443.91FLT3-IN-18
CAS:FLT3-IN-18: potent, selective FLT3 inhibitor, IC50 0.003 μM, induces apoptosis, G1 arrest, blocks FLT3/STAT5, potential in AML research.Formula:C26H36N8OColore e forma:SolidPeso molecolare:476.62FLT3/D835Y-IN-1
CAS:FLT3/D835Y-IN-1, an oral FLT3 inhibitor (IC50: FLT3 - 0.26 nM, D835Y - 0.18 nM), shows anticancer potential in AML research.Formula:C22H21N5O3Colore e forma:SolidPeso molecolare:403.43AGL 2043
CAS:AGL 2043 is a potent, reversible, ATP-competitive inhibitor of type III receptor tyrosine kinases.Formula:C15H12N4SColore e forma:SolidPeso molecolare:280.35MDK5466
CAS:MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death.Formula:C21H23N3OSPurezza:98%Colore e forma:SolidPeso molecolare:365.49PDGFRα/FLT3-ITD-IN-1
CAS:PDGFRα/FLT3-ITD-IN-1 are potent inhibitors of PDGFRα/FLT3, and their IC50 values are greater than 0.036 and 0.003 μM, respectively.Formula:C27H39N9OColore e forma:SolidPeso molecolare:505.66
