FLT
Gli inibitori della FLT (Fms-like tyrosine kinase) sono composti che prendono di mira i recettori FLT, coinvolti nella regolazione dell'angiogenesi attraverso la via del VEGF (fattore di crescita endoteliale vascolare). I recettori FLT svolgono un ruolo cruciale nello sviluppo di nuovi vasi sanguigni nei tumori. Inibendo i recettori FLT, è possibile ridurre efficacemente l'angiogenesi e la crescita tumorale, rendendo questi inibitori importanti nella terapia del cancro. Presso CymitQuimica, offriamo una selezione di inibitori della FLT di alta qualità per supportare la tua ricerca in oncologia, biologia vascolare e angiogenesi.
Trovati 87 prodotti per "FLT".
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AAE871
CAS:AAE871 is a type I FLT3 inhibitor.Formula:C24H34N8O2SColore e forma:SolidPeso molecolare:498.64FLT3-IN-6
CAS:FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.Formula:C23H25N5O3Colore e forma:SolidPeso molecolare:419.48JNJ-47117096 hydrochloride
CAS:JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.Formula:C21H23ClN4O2Colore e forma:SolidPeso molecolare:398.89FLT3/ITD-IN-2
CAS:FLT3/ITD-IN-2: Powerful FLT3/ITD, FLT3D835Y, and FLT3 inhibitor; hinders AML cell growth. IC50s: 0.3-1.0 nM.Formula:C23H26F3N7O2Colore e forma:SolidPeso molecolare:489.49FLT3-IN-4
CAS:FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenousFormula:C23H25N7O2Purezza:99.9%Colore e forma:SolidPeso molecolare:431.49Ref: TM-T11299
1mg87,00€5mg215,00€1mL*10mM (DMSO)235,00€10mg318,00€25mg510,00€50mg692,00€100mg888,00€500mg1.783,00€AXL-IN-13
CAS:AXL-IN-13: potent, oral AXL inhibitor, IC50=1.6nM, Kd=0.26nM, anti-cancer, inhibits EMT, cell migration & invasion.Formula:C34H41FN6O5Purezza:99.95%Colore e forma:SolidPeso molecolare:632.72FLT3/ITD-IN-3
CAS:FLT3/ITD-IN-3 (Compound 19) is a potent FLT3-ITD inhibitor with IC50 values: FLT3D835Y (0.3 nM), FLT3 (0.4 nM), inhibits AML cell proliferation.Formula:C22H26ClN7O2Colore e forma:SolidPeso molecolare:455.94KRN383
CAS:KRN383 inhibits ITD cell growth at ≤2.9 nM, erases ITD tumors in mice at 80 mg/kg dose, and may suit various treatment plans.Formula:C17H17N3O4Colore e forma:SolidPeso molecolare:327.33LBW242
CAS:LBW242: oral 3-mer Smac mimetic, IAP inhibitor, targets multiple myeloma, enhances TRAIL/chemo death in ovarian cancer, active on mutant FLT3 cells.Formula:C27H42N4O2Purezza:98%Colore e forma:SolidPeso molecolare:454.65FLT3-IN-12
CAS:FLT3-IN-12: potent, selective oral FLT3 inhibitor; FLT3-WT IC50: 1.48 nM, FLT3-D835Y: 2.87 nM; >1000x selective over c-KIT; anti-AML, IC50: 0.75 nM MV4-11.Formula:C21H23F3N6OColore e forma:SolidPeso molecolare:432.44FLT3-IN-15
CAS:FLT3-IN-15 is an orally active and potent FLT3 inhibitor, capable of acting on FLT3 (IC50: 0.87 nM) and FLT3/D835Y (IC50: 0.32 nM).Formula:C22H23ClFN5O2Colore e forma:SolidPeso molecolare:443.91GTP-14564
CAS:GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.Formula:C15H10N2OPurezza:99.81%Colore e forma:SolidPeso molecolare:234.25TAK-659
CAS:TAK-659 is a spleen tyrosine kinase (SYK) inhibitor.Formula:C17H21FN6OPurezza:98%Colore e forma:SolidPeso molecolare:344.39SG3-179
CAS:SG3-179 is a BET inhibitor.Formula:C28H35ClFN7O3SColore e forma:SolidPeso molecolare:604.14UNC4203
CAS:UNC4203 inhibits MERTK (1.2 nM), AXL (140 nM), TYRO3 (42 nM), FLT3 (90 nM); potent, selective, oral.Formula:C30H44N6OColore e forma:SolidPeso molecolare:504.71FLT3/ITD-IN-5
CAS:FLT3/ITD-IN-5 (Example 6) is an orally active inhibitor of both FLT3 and FLT3-ITD, exhibiting IC50 values of 0.088 nM and 0.348 nM, respectively. This compound is utilized in cancer research.Formula:C23H25N7O2Colore e forma:SolidPeso molecolare:431.49HPK1-IN-2 dihydrochloride
CAS:HPK1-IN-2 dihydrochloride, a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1) with an IC 50 of less than 0.05 µM, demonstrates significant antitumor activity. It additionally exhibits inhibition of Lck kinase activity, with an IC 50 ranging from 0.05 to less than 0.5 µM, and Flt3 kinase activity, with an IC 50 of less than 0.05 µM [1].Formula:C19H22Cl2N6OSColore e forma:SolidPeso molecolare:453.39OTS447
CAS:OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .Formula:C27H32ClN3O2Purezza:98.78%Colore e forma:Green SolidPeso molecolare:466.02TTT 3002
CAS:TTT 3002: oral FLT3 inhibitor for AML research, blocks D835 mutations, potent at 0.2 nM IC50.Formula:C27H23N5O3Colore e forma:SolidPeso molecolare:465.50Multi-kinase inhibitor 3
CAS:Multi-kinase inhibitor 3 (compound 12) is an orally active and effective multikinase (multikinase) inhibitor, demonstrating potent IC50 values against FLT1/VEGFR1, KDR/VEGFR2, FLT4/VEGFR3, FLT3, PDGFRα, and PDGFRβ, at 1.59, 1.23, 1.19, 0.59, 0.22, and 1.15 nM respectively. This compound exhibits anti-proliferative and anticancer activities.Formula:C26H26N6O2Colore e forma:SolidPeso molecolare:454.52
