c-Kit
Gli inibitori di c-Kit sono composti che bloccano l'attività del Recettore del Fattore di Cella Staminale (c-Kit), una tirosina chinasi che svolge un ruolo cruciale nella sopravvivenza, proliferazione e differenziazione cellulare, in particolare nelle cellule ematopoietiche. Le mutazioni di c-Kit sono associate a vari tipi di cancro, tra cui i tumori stromali gastrointestinali (GIST) e la leucemia. Presso CymitQuimica, offriamo inibitori di c-Kit per supportare la tua ricerca in oncologia, ematologia e biologia delle cellule staminali.
Trovati 102 prodotti di "c-Kit"
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ISCK03
CAS:<p>ISCK03 is a selective SCF/c-Kit inhibitor.</p>Formula:C19H21N3O2SPurezza:98.39%Colore e forma:SolidPeso molecolare:355.45JNJ-38158471
CAS:<p>JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .</p>Formula:C15H17ClN6O3Purezza:97.08%Colore e forma:SolidPeso molecolare:364.79OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Formula:C22H16F3N3O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:443.44Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Formula:C28H30N6OSPurezza:97.56% - >99.99%Colore e forma:SolidPeso molecolare:498.64Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Formula:C22H28FN4O6PPurezza:98.56%Colore e forma:SolidPeso molecolare:494.45BLU-263
CAS:<p>BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.</p>Formula:C27H29FN10OPurezza:99.01% - 99.67%Colore e forma:SolidPeso molecolare:528.58Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36SU14813
CAS:<p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>Formula:C23H27FN4O4Purezza:98.13%Colore e forma:SolidPeso molecolare:442.48Avapritinib
CAS:<p>Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.</p>Formula:C26H27FN10Purezza:96.59% - 99.7%Colore e forma:SolidPeso molecolare:498.56Multi-kinase inhibitor 1
CAS:<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Formula:C20H17F3N4O3Purezza:99.34%Colore e forma:SolidPeso molecolare:418.37Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formula:C24H24N4O5SPurezza:98.97% - 99.88%Colore e forma:SolidPeso molecolare:480.54Flumatinib
CAS:<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Formula:C29H29F3N8OPurezza:99.39% - 99.95%Colore e forma:SolidPeso molecolare:562.59AZD2932
CAS:<p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>Formula:C24H25N5O4Purezza:97.71% - 98.37%Colore e forma:SolidPeso molecolare:447.49AZD3229 Tosylate
CAS:<p>AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal</p>Formula:C31H34FN7O6SColore e forma:SolidPeso molecolare:651.71Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Formula:C35H30N4O4Purezza:97.61% - >99.99%Colore e forma:SolidPeso molecolare:570.64Dovitinib lactate
CAS:<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Formula:C24H27FN6O4Purezza:99.54% - 99.77%Colore e forma:SolidPeso molecolare:482.51Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Formula:C31H42N6O4Purezza:99.45% - ≥98%Colore e forma:White SolidPeso molecolare:562.7Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Formula:C23H25N7O2Purezza:99.05% - 99.57%Colore e forma:SolidPeso molecolare:431.49SKLB4771
CAS:<p>SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.</p>Formula:C25H27N7O3S2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:537.66AZD3229
CAS:<p>AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.</p>Formula:C24H26FN7O3Purezza:98.83%Colore e forma:SolidPeso molecolare:479.51
