IGF-1R
Gli inibitori di IGF-1R sono composti che prendono di mira specificamente il recettore del fattore di crescita insulino-simile 1 (IGF-1R), una tirosina chinasi recettore coinvolta nella crescita, sviluppo e sopravvivenza cellulare. La segnalazione dell'IGF-1R svolge un ruolo significativo nella progressione del cancro, rendendo questi inibitori preziosi nella ricerca oncologica. Presso CymitQuimica, offriamo inibitori di IGF-1R per supportare la tua ricerca in biologia del cancro, endocrinologia e sviluppo di terapie mirate.
Trovati 119 prodotti per "IGF-1R".
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GIP (human) acetate
GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.Purezza:98.65%Colore e forma:SolidTeprotumumab
CAS:Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.Purezza:/ - 95.2% (SDS-PAGE); 99.6% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.62 kDa (Predicted)Robatumumab
CAS:Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.Purezza:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.56 kDa (Predicted)MSDC-0602K
CAS:MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.Formula:C19H16KNO5SPurezza:99.42%Colore e forma:White SolidPeso molecolare:409.5NBI-31772
CAS:NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).Formula:C17H11NO7Purezza:99.37% - 99.79%Colore e forma:Yellow SolidPeso molecolare:341.27ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Formula:C23H28BrN7O3SPurezza:98.27%Colore e forma:White SolidPeso molecolare:562.483Ganitumab
CAS:Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.Purezza:100% (SEC-HPLC) - > 95%Colore e forma:Transparent LiquidPeso molecolare:145.70 kDa (Predicted)GIP (3-42), human
CAS:Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.Formula:C214H324N58O63SPurezza:95.73%Colore e forma:SolidPeso molecolare:4749.35HNMPA
CAS:HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.Formula:C11H11O4PPurezza:99.18%Colore e forma:SolidPeso molecolare:238.18AZ7550 hydrochloride
CAS:AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H32ClN7O2Purezza:99.65%Colore e forma:SolidPeso molecolare:522.042WAY-270250
CAS:WAY-270250 is an IGF-1R/SRC inhibitor.Formula:C18H16N2O2Purezza:99.97%Colore e forma:Green SolidPeso molecolare:292.33Cyclo(Gly-Pro)
CAS:Cyclo(Gly-Pro) is a cyclic dipeptide derived from the N-terminus of IGF-1. It has been shown to alleviate pain behaviors and inflammatory responses in mice.Formula:C7H10N2O2Peso molecolare:155.17GIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Formula:C162H240N40O47SPurezza:98%Colore e forma:SolidPeso molecolare:3531.94cis-NVP-ADW742
CAS:NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Formula:C28H31N5OColore e forma:SolidPeso molecolare:453.59IGF-I (24-41)
CAS:IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.Formula:C88H133N27O28Purezza:98%Colore e forma:SolidPeso molecolare:2017.16Acetyl Gastric Inhibitory Peptide (human)
CAS:Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.Formula:C228H340N60O67SColore e forma:SolidPeso molecolare:5025.6[D-Ala2]-GIP (human)
CAS:[D-Ala2]-GIP (human), GIP agonist (EC₅₀=630 pM), improves glucose/cognition, anti-neurotoxicity, for diabetes and Parkinson's.Formula:C226H338N60O66SPurezza:98%Colore e forma:SolidPeso molecolare:4983.58Insulin Aspart
CAS:Insulin Aspart is a rapid-acting insulin analog with faster absorption than human insulin, improving postprandial glycemic control.Purezza:99.86%Colore e forma:White SolidGIP, human
CAS:Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.Formula:C226H338N60O66SPurezza:98%Colore e forma:SolidPeso molecolare:4983.6IGF-1R inhibitor-2
CAS:IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Formula:C24H24FN7O2Colore e forma:SolidPeso molecolare:461.501
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