IGF-1R

Gli inibitori di IGF-1R sono composti che prendono di mira specificamente il recettore del fattore di crescita insulino-simile 1 (IGF-1R), una tirosina chinasi recettore coinvolta nella crescita, sviluppo e sopravvivenza cellulare. La segnalazione dell'IGF-1R svolge un ruolo significativo nella progressione del cancro, rendendo questi inibitori preziosi nella ricerca oncologica. Presso CymitQuimica, offriamo inibitori di IGF-1R per supportare la tua ricerca in biologia del cancro, endocrinologia e sviluppo di terapie mirate.

Trovati 119 prodotti per "IGF-1R".

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prodotti per pagina.

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Ganitumab
CAS:
- 905703-97-1
Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.
Purezza:100% (SEC-HPLC) - > 95%
Colore e forma:Transparent Liquid
Peso molecolare:145.70 kDa (Predicted)
Ref: TM-T76810
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ALK inhibitor 1
CAS:
- 761436-81-1
ALK inhibitor 1 is a selective ALK kinase inhibitor.
Formula:C₂₃H₂₈BrN₇O₃S
Purezza:98.27%
Colore e forma:White Solid
Peso molecolare:562.483
Ref: TM-T10285
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GIP (3-42), human
CAS:
- 1802086-25-4
Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.
Formula:C₂₁₄H₃₂₄N₅₈O₆₃S
Purezza:95.73%
Colore e forma:Solid
Peso molecolare:4749.35
Ref: TM-T37589
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Robatumumab
CAS:
- 934235-44-6
Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.
Purezza:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)
Colore e forma:Transparent Liquid
Peso molecolare:145.56 kDa (Predicted)
Ref: TM-T76759
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NBI-31772
CAS:
- 374620-70-9
NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).
Formula:C₁₇H₁₁NO₇
Purezza:99.37% - 99.79%
Colore e forma:Yellow Solid
Peso molecolare:341.27
Ref: TM-T8906
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MSDC-0602K
CAS:
- 1314533-27-1
MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.
Formula:C₁₉H₁₆KNO₅S
Purezza:99.42%
Colore e forma:White Solid
Peso molecolare:409.5
Ref: TM-T38715
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Teprotumumab
CAS:
- 1036734-93-6
Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.
Purezza:/ - 95.2% (SDS-PAGE); 99.6% (SEC-HPLC)
Colore e forma:Transparent Liquid
Peso molecolare:145.62 kDa (Predicted)
Ref: TM-T76727
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GIP (human) acetate
GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.
Purezza:98.65%
Colore e forma:Solid
Ref: TM-TP2018L
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AZ7550 hydrochloride
CAS:
- 2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:C₂₇H₃₂ClN₇O₂
Purezza:99.65%
Colore e forma:Solid
Peso molecolare:522.042
Ref: TM-T13564L
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HNMPA
CAS:
- 132541-52-7
HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.
Formula:C₁₁H₁₁O₄P
Purezza:99.18%
Colore e forma:Solid
Peso molecolare:238.18
Ref: TM-T21761
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Acetyl Gastric Inhibitory Peptide (human)
CAS:
- 299898-33-2
Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.
Formula:C₂₂₈H₃₄₀N₆₀O₆₇S
Colore e forma:Solid
Peso molecolare:5025.6
Ref: TM-T76310
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Gastric Inhibitory Peptide (1-42) (porcine) TFA
Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.
Formula:C₂₂₅H₃₄₂N₆₀O₆₆S·XCF₃COOH
Colore e forma:White Solid
Peso molecolare:4975.55
Ref: TM-T83694
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IGF-I (24-41)
CAS:
- 135861-49-3
IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.
Formula:C₈₈H₁₃₃N₂₇O₂₈
Purezza:98%
Colore e forma:Solid
Peso molecolare:2017.16
Ref: TM-TP1124
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WAY-270250
CAS:
- 852367-46-5
WAY-270250 is an IGF-1R/SRC inhibitor.
Formula:C₁₈H₁₆N₂O₂
Purezza:99.97%
Colore e forma:Green Solid
Peso molecolare:292.33
Ref: TM-T77624
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GIP, human
CAS:
- 100040-31-1
Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.
Formula:C₂₂₆H₃₃₈N₆₀O₆₆S
Purezza:98%
Colore e forma:Solid
Peso molecolare:4983.6
Ref: TM-TP2018
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Insulin peglispro
CAS:
- 1200440-65-8
Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.
Formula:C₃₇₀H₅₆₆N₁₀₄O₁₁₀S₄
Colore e forma:Solid
Peso molecolare:8359.32
Ref: TM-T76540
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(Pro3) GIP, human
CAS:
- 299898-52-5
(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.
Formula:C₂₂₆H₃₃₈N₆₀O₆₄S
Colore e forma:Solid
Peso molecolare:4951.53
Ref: TM-T76313
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IGF-1R inhibitor-2
CAS:
- 1116236-15-7
IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.
Formula:C₂₄H₂₄FN₇O₂
Colore e forma:Solid
Peso molecolare:461.501
Ref: TM-T38502
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cis-NVP-ADW742
CAS:
- 475489-15-7
NVP-ADW742 is an IGF-1R inhibitor with IC₅₀ of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
Formula:C₂₈H₃₁N₅O
Colore e forma:Solid
Peso molecolare:453.59
Ref: TM-T2107
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[D-Ala2]-GIP (human)
CAS:
- 444073-04-5
[D-Ala2]-GIP (human), GIP agonist (EC₅₀=630 pM), improves glucose/cognition, anti-neurotoxicity, for diabetes and Parkinson's.
Formula:C₂₂₆H₃₃₈N₆₀O₆₆S
Purezza:98%
Colore e forma:Solid
Peso molecolare:4983.58
Ref: TM-TP2019