Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1495 prodotti di "Autofagia"
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SU9516
CAS:SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formula:C13H11N3O2Purezza:99.34% - 99.96%Colore e forma:SolidPeso molecolare:241.25Ref: TM-T6167
1mg35,00€2mg50,00€5mg73,00€10mg103,00€25mg208,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)74,00€10058-F4
CAS:10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.Formula:C12H11NOS2Purezza:98% - 99.87%Colore e forma:SolidPeso molecolare:249.35Soyasapogenol B
CAS:Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.Formula:C30H50O3Purezza:99.51% - 99.81%Colore e forma:SolidPeso molecolare:458.72CZC-25146
CAS:CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).Formula:C22H25FN6O4SPurezza:97.68%Colore e forma:SolidPeso molecolare:488.54N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Formula:C25H37NOPurezza:98.7% - 99.92%Colore e forma:SolidPeso molecolare:367.57Ref: TM-TN1965
1mg86,00€5mg180,00€10mg274,00€25mg465,00€50mg663,00€100mg919,00€200mg1.216,00€1mL*10mM (DMSO)187,00€Amsacrine hydrochloride
CAS:Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.Formula:C21H20ClN3O3SPurezza:99.05% - 99.92%Colore e forma:SolidPeso molecolare:429.92Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurezza:97.16% - 99.63%Colore e forma:Almost White SolidPeso molecolare:383.37Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formula:C26H22N2O2Purezza:97.12% - 99.96%Colore e forma:SolidPeso molecolare:394.47Ref: TM-T6671
2mg43,00€5mg58,00€10mg93,00€25mg178,00€50mg343,00€100mg509,00€500mg1.121,00€1mL*10mM (DMSO)58,00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.88%Colore e forma:SolidPeso molecolare:294.39GNE-9605
CAS:GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).Formula:C17H20ClF4N7OPurezza:98.55% - 98.75%Colore e forma:SolidPeso molecolare:449.83PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purezza:97% - 99.79%Colore e forma:SolidPeso molecolare:394.12Ref: TM-T6961
1mg42,00€5mg88,00€10mg137,00€25mg205,00€50mg276,00€100mg434,00€200mg638,00€1mL*10mM (DMSO)88,00€Rotenone
CAS:Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formula:C23H22O6Purezza:89.58% - 99.88%Colore e forma:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecolare:394.42SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:264.12Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.
Formula:C24H25ClFN5O3Purezza:98.56% - 99.9%Colore e forma:Off-White SolidPeso molecolare:485.94Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purezza:99.51% - 99.61%Colore e forma:SolidPeso molecolare:526.88Ref: TM-T4367
1mg50,00€5mg94,00€10mg165,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)110,00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purezza:98.81% - 99.65%Colore e forma:SolidPeso molecolare:624.77Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purezza:99.75% - 99.94%Colore e forma:SolidPeso molecolare:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purezza:99.91%Colore e forma:White To Off-White PowderPeso molecolare:290.1Wogonoside
CAS:Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.
Formula:C22H20O11Purezza:98.24% - >99.99%Colore e forma:SolidPeso molecolare:460.39Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurezza:99.58% - 99.88%Colore e forma:SolidPeso molecolare:413.49
