Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1483 prodotti di "Autofagia"
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Lycorine hydrochloride
CAS:<p>Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.</p>Formula:C16H18ClNO4Purezza:99.45% - 99.49%Colore e forma:Fine Crystal PowderPeso molecolare:323.77Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Formula:C33H45ClN4O9Purezza:98.22% - >99.99%Colore e forma:Pale Yellow To Yellow Crystalline PowderPeso molecolare:677.18Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Formula:C20H21N5O6Purezza:98.1% - 99.92%Colore e forma:Similar To White PowderPeso molecolare:427.41Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Formula:C15H22N2OPurezza:99.55%Colore e forma:SolidPeso molecolare:246.35Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Formula:C21H23N7O2SPurezza:98.78% - 99.85%Colore e forma:White PowderPeso molecolare:437.52Nitazoxanide
CAS:Nitazoxanide (NSC-697855) is a synthetic benzamide antiprotozoal; it disrupts pyruvate electron transfer reactions.Formula:C12H9N3O5SPurezza:99% - 99.93%Colore e forma:SolidPeso molecolare:307.28Xylitol
CAS:Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group.Formula:C5H12O5Purezza:99.89% - 99.96%Colore e forma:White Solid PowderPeso molecolare:152.15Pepstatin
CAS:Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formula:C34H63N5O9Purezza:96.74% - 99.94%Colore e forma:SolidPeso molecolare:685.89Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purezza:98.98% - 99.9%Colore e forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecolare:530.45Etoposide
CAS:<p>Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).</p>Formula:C29H32O13Purezza:99.19% - 99.94%Colore e forma:Crystals From Methanol SolidPeso molecolare:588.56Monacolin J
CAS:Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Formula:C19H28O4Purezza:98.06%Colore e forma:SolidPeso molecolare:320.42Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formula:C21H26Cl2F3N3SPurezza:99.57% - 99.96%Colore e forma:Cream Fine PowderPeso molecolare:480.43Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formula:C25H28N8O2Purezza:99.15% - >99.99%Colore e forma:SolidPeso molecolare:472.54Bromhexine hydrochloride
CAS:Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.Formula:C14H21Br2ClN2Purezza:99.98%Colore e forma:White SolidPeso molecolare:412.59Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purezza:98% - 99.91%Colore e forma:Crystals From Ether (Ntp 1992)Peso molecolare:392.46Salicylic acid
CAS:Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Formula:C7H6O3Purezza:98.04% - 98.83%Colore e forma:White Solid PowderPeso molecolare:138.12TRAF6 peptide
CAS:TRAF6 peptide inhibits TRAF6-p62, blocks TrkA ubiquitination, and shows promise for neurological disease research.Formula:C145H238N34O44Colore e forma:SolidPeso molecolare:3161.64Fumagilin-105
CAS:<p>Fumagilin-105, an autophagy-targeting chimera (AUTOTAC), induces self-oligomerization of p62 and exhibits a DC50 of 0.7 μM against MetAP2 in HEK293 cells.</p>Formula:C46H60N2O9Colore e forma:SolidPeso molecolare:784.98SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Formula:C22H26N4O5Colore e forma:SolidPeso molecolare:426.47LC3in-C42
LC3in-C42 is a covalent inhibitor of LC3A/B and autophagy active within cells. Selectively inhibiting the binding of P62 to LC3A/B both in vitro and at the cellular level, LC3in-C42 functions similarly to D5 and is effective at lower concentrations.Colore e forma:Odour Solid
