Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1527 prodotti per "Autofagia".
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Binimetinib-13C-D3
Binimetinib-13C-d3 (MEK162) is an isotopically labelled compound of Binimetinib.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor melanoma.Formula:C17H15BrF2N4O3Colore e forma:SolidPeso molecolare:445.24LG100268
CAS:LG100268 is a selective, and oral RXR agonist，inducing transcriptional activation in adipocytes; inhibits keratin 17 increases PD-L1 expression.Formula:C24H29NO2Purezza:99.83%Colore e forma:SolidPeso molecolare:363.49TRAF6 peptide TFA
TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.Formula:C145H238N34O44·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:3161.64 (free acid)Rosuvastatin-D3 Sodium
CAS:Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).Formula:C22H24D3FN3NaO6SPurezza:98%Colore e forma:SolidPeso molecolare:506.54KN-93 hydrochloride
CAS:KN-93 hydrochloride is a reversible, competitive CaMKII inhibitor inducing reversible G1 arrest, supporting cell cycle and signaling pathway studies.Formula:C26H30Cl2N2O4SPurezza:99.99%Colore e forma:White SolidPeso molecolare:537.5Loperamide hydrochloride (Standard)
CAS:Loperamide hydrochloride (Standard) is the standard substance of Loperamide hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Formula:C29H34Cl2N2O2Peso molecolare:513.50Wortmannin (Standard)
CAS:Wortmannin (Standard) is the standard substance of Wortmannin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.Formula:C23H24O8Peso molecolare:428.43Nitrendipine (Standard)
CAS:Nitrendipine (Standard) is the standard substance of Nitrendipine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.Formula:C18H20N2O6Peso molecolare:360.36Imiquimod (Standard)
CAS:Imiquimod (Standard) is the standard substance of Imiquimod, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.Formula:C14H16N4Peso molecolare:240.30Ezetimibe-D4
CAS:Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activationFormula:C24H21F2NO3Purezza:98%Colore e forma:SolidPeso molecolare:413.45Rapalink-1
CAS:Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.Formula:C91H138N12O24Purezza:98%Colore e forma:White ViscousPeso molecolare:1784.14BI-9627 hydrochloride
CAS:BI-9627 hydrochloride is a potent NHE1 inhibitor (IC₅₀ 6 nM, 31 nM), highly selective over NHE2, inactive on NHE3, regulating pH and autophagy.Formula:C16H20ClF3N4O2Purezza:99.91%Colore e forma:White SolidPeso molecolare:392.8Pemetrexed disodium heptahydrate
CAS:Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.Formula:C20H33N5Na2O13Purezza:99.78%Colore e forma:White SolidPeso molecolare:597.49Erlotinib-D6 hydrochloride
CAS:Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Formula:C22H24ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:435.93PS372424 hydrochloride
CAS:PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Formula:C33H45ClN6O4Purezza:95.03%Colore e forma:Transparent ViscousPeso molecolare:625.2Ponatinib-D8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formula:C29H27F3N6OPurezza:98%Colore e forma:SolidPeso molecolare:540.61Guanidine hydrochloride (Standard)
CAS:Guanidine hydrochloride (Standard) is the standard substance of Guanidine hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.Formula:CH6ClN3Colore e forma:SolidPeso molecolare:95.53Clotrimazole (Standard)
CAS:Clotrimazole (Standard) is the standard substance of Clotrimazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.Formula:C22H17ClN2Colore e forma:SolidPeso molecolare:344.84Colistin sulfate (Standard)
CAS:Colistin sulfate (Standard) is the standard substance of Colistin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Colore e forma:SolidAnti-LRRK2 Antibody (1C773)
Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.Colore e forma:Odour Liquid
