Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1490 prodotti di "Autofagia"
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Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormula:C21H15ClF4N4O3Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:482.82Ref: TM-T1792
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)57,00€Enalaprilat Dihydrate
CAS:Enalaprilat Dihydrate (MK-422 Dihydrate) （IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.Formula:C18H24N2O5·2H2OPurezza:99.46% - 99.78%Colore e forma:SolidPeso molecolare:348.43BDO
CAS:3BDO is a new mTOR activator. 3BDO inhibits autophagy.Formula:C18H17NO5Purezza:97.76%Colore e forma:SolidPeso molecolare:327.33Ref: TM-T14033
1mg35,00€2mg47,00€5mg67,00€10mg97,00€25mg207,00€50mg329,00€100mg494,00€1mL*10mM (DMSO)74,00€(+)-JQ-1
CAS:(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formula:C23H25ClN4O2SPurezza:97.57% - 99.97%Colore e forma:SolidPeso molecolare:456.99Ref: TM-T2110
1mg34,00€2mg42,00€5mg57,00€10mg74,00€25mg90,00€50mg137,00€100mg178,00€200mg268,00€500mg485,00€1mL*10mM (DMSO)63,00€SR9009
CAS:SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.Formula:C20H24ClN3O4SPurezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:437.94Ref: TM-T3685
2mg42,00€5mg62,00€10mg87,00€25mg144,00€50mg250,00€100mg405,00€200mg600,00€1mL*10mM (DMSO)67,00€LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Formula:C31H38N8O3Purezza:98% - 98.82%Colore e forma:SolidPeso molecolare:570.69Mavorixafor trihydrochloride
CAS:Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.Formula:C21H30Cl3N5Purezza:98.00%Colore e forma:SolidPeso molecolare:458.86Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:432.46PHA-665752
CAS:PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.Formula:C32H34Cl2N4O4SPurezza:97.05% - 98.82%Colore e forma:SolidPeso molecolare:641.61Oleanolic Acid
CAS:Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.Formula:C30H48O3Purezza:97.04% - 98.51%Colore e forma:SolidPeso molecolare:456.70GW 4064
CAS:GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).Formula:C28H22Cl3NO4Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:542.84Ref: TM-T2233
5mg52,00€10mg79,00€25mg132,00€50mg222,00€100mg403,00€200mg605,00€500mg954,00€1mL*10mM (DMSO)59,00€Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purezza:99.69%Colore e forma:SolidPeso molecolare:500.83Ref: TM-T1792L
5mg35,00€10mg48,00€25mg69,00€50mg88,00€100mg140,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)58,00€Tropifexor
CAS:Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.
Formula:C29H25F4N3O5SPurezza:99.3% - 99.85%Colore e forma:SolidPeso molecolare:603.58Ref: TM-T4379
1mg87,00€5mg166,00€10mg248,00€25mg437,00€50mg665,00€100mg1.008,00€200mg1.520,00€500mg2.252,00€BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formula:C10H9NO2SPurezza:98% - 99.92%Colore e forma:SolidPeso molecolare:207.25Ref: TM-T1902
5mg50,00€10mg57,00€25mg96,00€50mg170,00€100mg265,00€200mg399,00€500mg662,00€1mL*10mM (DMSO)52,00€ZSTK474
CAS:PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potentialFormula:C19H21F2N7O2Purezza:98.29% - 99.95%Colore e forma:White PowderPeso molecolare:417.41JZL195
CAS:JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.Formula:C24H23N3O5Purezza:99.81%Colore e forma:SolidPeso molecolare:433.46SRT 1720
CAS:SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.Formula:C25H23N7OSPurezza:98.84%Colore e forma:SolidPeso molecolare:469.56Vancomycin
CAS:Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibitingFormula:C66H75Cl2N9O24Purezza:98.76% - 99.52%Colore e forma:Almost White PowderPeso molecolare:1449.25Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Formula:C26H44O4Purezza:99.88% - 99.97%Colore e forma:SolidPeso molecolare:420.63Ref: TM-T1789
5mg46,00€10mg50,00€25mg78,00€50mg94,00€100mg155,00€200mg259,00€500mg477,00€1mL*10mM (DMSO)50,00€Genipin
CAS:Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.Formula:C11H14O5Purezza:99.09% - 99.21%Colore e forma:SolidPeso molecolare:226.23
