Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1492 prodotti di "Autofagia"
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Sepantronium bromide
CAS:Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Formula:C20H19BrN4O3Purezza:99.68% - 99.85%Colore e forma:SolidPeso molecolare:443.26LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purezza:98% - 99.96%Colore e forma:Pale Yellow SolidPeso molecolare:307.34PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurezza:98.74% - 99.19%Colore e forma:SolidPeso molecolare:347.393'-Hydroxypterostilbene
CAS:3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.Formula:C16H16O4Purezza:98.25% - 99.19%Colore e forma:SolidPeso molecolare:272.3BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurezza:98% - 99.82%Colore e forma:SolidPeso molecolare:318.76Sapanisertib
CAS:Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formula:C15H15N7OPurezza:99.19% - >99.99%Colore e forma:SolidPeso molecolare:309.33Ref: TM-T1838
1mg40,00€2mg51,00€5mg85,00€10mg96,00€25mg160,00€50mg235,00€100mg350,00€500mg838,00€1mL*10mM (DMSO)88,00€Flavopiridol hydrochloride
CAS:Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.Formula:C21H21Cl2NO5Purezza:98.87% - 99.88%Colore e forma:SolidPeso molecolare:438.3Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formula:C6H8N2O2SPurezza:99.72% - 99.96%Colore e forma:White To Pale Cream Crystalline Powder Or CrystalsPeso molecolare:172.2Doramapimod HCl
CAS:Doramapimod HCl, a p38MAPK inhibitor in clinical trials for autoimmune diseases, has slow binding kinetics.Formula:C31H38ClN5O3Colore e forma:SolidPeso molecolare:564.13AGN 193109
CAS:AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).Formula:C28H24O2Purezza:99.87% - 99.89%Colore e forma:SolidPeso molecolare:392.49Ref: TM-TQ0097
2mg95,00€5mg144,00€10mg222,00€25mg401,00€50mg620,00€100mg888,00€1mL*10mM (DMSO)152,00€MPP+ iodide
CAS:MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.Formula:C12H12INPurezza:99.49% - 99.96%Colore e forma:SolidPeso molecolare:297.13GSK2578215A
CAS:GSK2578215A is a potent and selective LRRK2 kinase inhibitor.Formula:C24H18FN3O2Purezza:99.57% - 99.94%Colore e forma:SolidPeso molecolare:399.42Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurezza:99.42% - 99.94%Colore e forma:Off White PowderPeso molecolare:493.6Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purezza:94.54% - 99.86%Colore e forma:SolidPeso molecolare:338.35Ref: TM-T6S1683
5mg44,00€10mg55,00€25mg93,00€50mg158,00€100mg224,00€200mg330,00€1mL*10mM (DMSO)55,00€Cilofexor tromethamine
CAS:Cilofexor (GS-9674), a nonsteroidal FXR agonist, reduces cholestasis and liver damage in PSC, showing safety and efficacy in trials.Formula:C32H33Cl3N4O8Colore e forma:SolidPeso molecolare:707.99Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purezza:98% - 99.88%Colore e forma:Yellow Crystalline PowderPeso molecolare:232.36Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purezza:98.97% - 99.62%Colore e forma:SolidPeso molecolare:246.3Ref: TM-TQ0165
1mg88,00€2mgPrezzo su richiesta5mg240,00€10mg360,00€25mg518,00€50mg692,00€100mg1.035,00€200mg1.388,00€1mL*10mM (DMSO)310,00€Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formula:C15H18O8Purezza:98.81% - 99.92%Colore e forma:White SolidPeso molecolare:326.30Amsacrine gluconate
CAS:Amsacrine gluconate: an aminoacridine with anticancer properties, possibly works by intercalating DNA and inhibiting topoisomerase II.Formula:C27H31N3O10SColore e forma:SolidPeso molecolare:589.62Apocynin
CAS:Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).Formula:C9H10O3Purezza:99.71% - 99.98%Colore e forma:Yellowish To Brown PowderPeso molecolare:166.17
