Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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STF-62247
CAS:STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.Formula:C15H13N3SPurezza:99.6% - 99.67%Colore e forma:SolidPeso molecolare:267.35Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formula:C26H33NO2Purezza:98% - 99.68%Colore e forma:Yellow PowderPeso molecolare:391.55CD437
CAS:CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Formula:C27H26O3Purezza:98.92% - 99.63%Colore e forma:SolidPeso molecolare:398.49FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purezza:99.66% - 99.95%Colore e forma:SolidPeso molecolare:208.21LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Formula:C31H38N8O3Purezza:98% - 98.82%Colore e forma:SolidPeso molecolare:570.69Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14H-89 dihydrochloride
CAS:H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).Formula:C20H20BrN3O2S·2HClPurezza:98.22% - >99.99%Colore e forma:SolidPeso molecolare:519.28Ref: TM-T6250
5mg39,00€10mg58,00€25mg106,00€50mg202,00€100mg344,00€200mg512,00€500mg815,00€1mL*10mM (DMSO)52,00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purezza:98.63% - >99.99%Colore e forma:Yellow SolidPeso molecolare:267.28Ref: TM-T2623
5mg38,00€10mg50,00€25mg78,00€50mg101,00€100mg168,00€200mg250,00€500mg421,00€1mL*10mM (DMSO)55,00€ML327
CAS:ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formula:C19H18N4O4Purezza:98.47%Colore e forma:SolidPeso molecolare:366.37Ref: TM-T4252
1mg47,00€2mg62,00€5mg92,00€10mg137,00€25mg222,00€50mg356,00€100mg612,00€200mg850,00€1mL*10mM (DMSO)101,00€Sitagliptin phosphate
CAS:Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.Formula:C16H18F6N5O5PPurezza:99.72% - 99.91%Colore e forma:White SolidPeso molecolare:505.31KN-92 phosphate
CAS:KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.Formula:C24H28ClN2O7PSPurezza:99.86%Colore e forma:SolidPeso molecolare:554.98Ref: TM-T4530
2mg34,00€5mg66,00€10mg100,00€25mg166,00€50mg245,00€100mg349,00€200mg495,00€1mL*10mM (DMSO)80,00€Wortmannin
CAS:Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formula:C23H24O8Purezza:95.84% - 99.77%Colore e forma:White SolidPeso molecolare:428.43Ref: TM-T6283
1mg38,00€2mg49,00€5mg80,00€10mg119,00€25mg235,00€50mg406,00€100mg602,00€1mL*10mM (DMSO)88,00€Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurezza:98.73% - 98.87%Colore e forma:SolidPeso molecolare:486.8Ref: TM-T8399
5mg34,00€10mg50,00€25mg78,00€50mg94,00€100mg131,00€200mg162,00€500mg215,00€1mL*10mM (DMSO)56,00€Danusertib
CAS:Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formula:C26H30N6O3Purezza:97.88% - 98.79%Colore e forma:White PowderPeso molecolare:474.553-Methyladenine
CAS:3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formula:C6H7N5Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:149.15WYC-209
CAS:WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Formula:C20H20N2O3SPurezza:99.77%Colore e forma:SolidPeso molecolare:368.45Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurezza:99.45%Colore e forma:SolidPeso molecolare:358.54Ref: TM-T6163
5mg34,00€10mg50,00€25mg90,00€50mg150,00€100mg210,00€200mg344,00€500mg567,00€1mL*10mM (DMSO)56,00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formula:C26H37ClN6O2Purezza:98.19%Colore e forma:SolidPeso molecolare:501.07Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purezza:98.11% - 99.87%Colore e forma:SolidPeso molecolare:718.08TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Formula:C20H13F2N3Purezza:99.35% - 99.79%Colore e forma:SolidPeso molecolare:333.33Ref: TM-T4646
5mg37,00€10mg55,00€25mg99,00€50mg152,00€100mg230,00€500mgPrezzo su richiesta1mL*10mM (DMSO)40,00€
