Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Formula:C22H19ClN2O6SPurezza:99.45%Colore e forma:SolidPeso molecolare:474.91Ref: TM-T4398
2mg34,00€5mg50,00€10mg79,00€25mg130,00€50mg216,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)55,00€Cabergoline diphosphate
CAS:Cabergoline, a D2 receptor agonist, treats prolactinomas by normalizing prolactin levels.Formula:C26H43N5O10P2Colore e forma:SolidPeso molecolare:647.6PF-4708671
CAS:PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formula:C19H21F3N6Purezza:99.48% - 99.98%Colore e forma:SolidPeso molecolare:390.41Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purezza:95% - 99.19%Colore e forma:Yellow To Orange SolidPeso molecolare:383.83Ref: TM-T3419
2mg34,00€5mg50,00€10mg84,00€25mg145,00€50mg205,00€100mg289,00€200mg432,00€1mL*10mM (DMSO)65,00€BI-D1870
CAS:BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.Formula:C19H23F2N5O2Purezza:98.51% - 99.43%Colore e forma:SolidPeso molecolare:391.42VLX600
CAS:VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formula:C17H15N7Purezza:98.62%Colore e forma:SolidPeso molecolare:317.35Ganoderic acid A
CAS:Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formula:C30H44O7Purezza:99.31% - ≥95%Colore e forma:SolidPeso molecolare:516.67Ref: TM-T6S1141
1mg44,00€5mg92,00€10mg152,00€25mg236,00€50mg354,00€100mg518,00€1mL*10mM (DMSO)104,00€PAC-1
CAS:PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.
Formula:C23H28N4O2Purezza:96.78% - 99.77%Colore e forma:SolidPeso molecolare:392.49Bromocriptine mesylate
CAS:Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)Formula:C33H44BrN5O8SPurezza:99.85% - 99.96%Colore e forma:White SolidPeso molecolare:750.7Berbamine
CAS:Berbamine is a natural product extracted from Phellodendron amurense.Formula:C37H40N2O6Purezza:98.92% - 99.67%Colore e forma:White Crystal PowderPeso molecolare:608.72Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Formula:C24H21F2NO4Purezza:99.56% - >99.99%Colore e forma:SolidPeso molecolare:425.42Ref: TM-T6130
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg208,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€SR9011
CAS:SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBα; IC50: 560 nM, REV-ERBβ).Formula:C23H31ClN4O3SPurezza:99.64% - 99.65%Colore e forma:SolidPeso molecolare:479.042-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purezza:98% - 99.95%Colore e forma:Off-White SolidPeso molecolare:302.41Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurezza:99.25% - >99.99%Colore e forma:SolidPeso molecolare:259.33Ref: TM-T1847
5mg35,00€10mg49,00€25mg82,00€50mg113,00€100mg170,00€200mg250,00€500mg419,00€1mL*10mM (DMSO)52,00€Fendiline
CAS:Fendiline: coronary vasodilator, calcium blocker, potential antiarrhythmic/antianginal.Formula:C23H25NColore e forma:SolidPeso molecolare:315.45DMOG
CAS:DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.
Formula:C6H9NO5Purezza:80.23% - 99.98%Colore e forma:SolidPeso molecolare:175.14KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formula:C38H35N5O6S2Purezza:99.80% - >99.99%Colore e forma:White SolidPeso molecolare:721.84Ref: TM-T2694
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg207,00€50mg404,00€100mg592,00€1mL*10mM (DMSO)105,00€Adezmapimod
CAS:Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.Formula:C21H16FN3OSPurezza:99.42% - 99.93%Colore e forma:White SolidPeso molecolare:377.43Heparin sodium salt
CAS:Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.Formula:C26H42N2NaO37S5Purezza:98%Colore e forma:SolidPeso molecolare:1157.89Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purezza:98.76% - >99.99%Colore e forma:SolidPeso molecolare:272.25Ref: TM-T6427
1mg40,00€2mg52,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€1mL*10mM (DMSO)82,00€
