Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Formula:C21H18F3NO3S2Purezza:98.91% - 99.64%Colore e forma:White SolidPeso molecolare:453.50Gambogic Acid
CAS:Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.Formula:C38H44O8Purezza:97.16% - 98.67%Colore e forma:SolidPeso molecolare:628.75Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:404.36Ref: TM-T3043
1g583,00€5mg49,00€10mg62,00€25mg78,00€50mg92,00€100mg138,00€200mg215,00€500mg395,00€1mL*10mM (DMSO)56,00€Perifosine
CAS:Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.Formula:C25H52NO4PPurezza:99.80 - >99.99%Colore e forma:SolidPeso molecolare:461.66Atorvastatin strontium
CAS:Atorvastatin strontium lowers cholesterol, prevents heart disease, and treats dyslipidemia by inhibiting HMG-CoA reductase.Formula:C66H68F2N4O10SrColore e forma:SolidPeso molecolare:1202.9GANT 61
CAS:GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.
Formula:C27H35N5Purezza:97.59% - >99.99%Colore e forma:SolidPeso molecolare:429.6UVI 3003
CAS:UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.Formula:C28H36O4Purezza:99.82%Colore e forma:SolidPeso molecolare:436.58Ref: TM-T17209
1mg35,00€2mg52,00€5mg74,00€10mg119,00€25mg243,00€50mg406,00€100mg607,00€1mL*10mM (DMSO)86,00€Dansylcadaverine
CAS:Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.Formula:C17H25N3O2SPurezza:98.33% - 99.6%Colore e forma:SolidPeso molecolare:335.46Pemetrexed disodium hemipenta hydrate
CAS:Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.Formula:C20H21N5O6·2NaH2OPurezza:98.76%Colore e forma:SolidPeso molecolare:518.43SD 0006
CAS:SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formula:C20H20ClN5O2Purezza:98.32%Colore e forma:SolidPeso molecolare:397.86Ref: TM-T7276
2mg35,00€5mg55,00€10mg86,00€25mg138,00€50mg215,00€100mg319,00€200mg447,00€1mL*10mM (DMSO)62,00€BAR502
CAS:BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).Formula:C25H44O3Purezza:99.95%Colore e forma:SolidPeso molecolare:392.62Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purezza:95.10% - 99.3% （SEC-HPLC）Colore e forma:LiquidPeso molecolare:144.6 kDaDacinostat
CAS:LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is an activator of the p21 promoter.Formula:C22H25N3O3Purezza:95.28% - 97.88%Colore e forma:SolidPeso molecolare:379.45Ref: TM-T2454
1mg50,00€2mg64,00€5mg104,00€10mg170,00€25mg305,00€50mg462,00€100mg668,00€500mg1.369,00€1mL*10mM (DMSO)104,00€PPQ-102
CAS:PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).Formula:C26H22N4O3Purezza:98.80% - ≥95%Colore e forma:SolidPeso molecolare:438.48Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
Myristoylated autocamtide-2-related inhibitory peptide acetate is a cell-permeable CaM kinase II inhibitor.Formula:C80H146N22O22Purezza:97.03%Colore e forma:SolidPeso molecolare:1768.15Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purezza:99.4% - 99.8%Colore e forma:Light Yellow PowderPeso molecolare:312.45Ref: TM-T5574
1mg34,00€5mg50,00€10mg93,00€25mg152,00€50mg205,00€100mg289,00€200mg432,00€1mL*10mM (DMSO)55,00€SR-18292
CAS:SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.Formula:C23H30N2O2Purezza:99.16% - 99.91%Colore e forma:SolidPeso molecolare:366.5Ref: TM-T4353
2mg40,00€5mg60,00€10mg87,00€25mg180,00€50mg283,00€100mg449,00€500mg938,00€1mL*10mM (DMSO)71,00€SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Formula:C19H20FN5OPurezza:99.13% - 99.68%Colore e forma:SolidPeso molecolare:353.39Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purezza:97.76% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:1030.29CA77.1
CAS:CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).Formula:C16H12ClN3OPurezza:99.50%Colore e forma:SolidPeso molecolare:297.74
