Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1490 prodotti di "Autofagia"
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Enzalutamide
CAS:Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formula:C21H16F4N4O2SPurezza:99% - 99.93%Colore e forma:SolidPeso molecolare:464.44Ref: TM-T6002
5mg48,00€10mg56,00€25mg74,00€50mg96,00€100mg154,00€200mg187,00€500mg274,00€1mL*10mM (DMSO)52,00€Arctigenin
CAS:(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formula:C21H24O6Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:372.41PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purezza:99.22%Colore e forma:SolidPeso molecolare:185.22Ref: TM-T6954
5mg49,00€10mg70,00€25mg133,00€50mg195,00€100mg349,00€200mg518,00€500mg830,00€1mL*10mM (DMSO)54,00€Fexaramine
CAS:Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formula:C32H36N2O3Purezza:98.87% - 99.61%Colore e forma:SolidPeso molecolare:496.64GSK2656157
CAS:GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.Formula:C23H21FN6OPurezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:416.45Ref: TM-T2654
2mg35,00€5mg50,00€10mg81,00€25mg142,00€50mg259,00€100mg467,00€200mg632,00€1mL*10mM (DMSO)56,00€PD-166866
CAS:PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formula:C20H24N6O3Purezza:98.29%Colore e forma:SolidPeso molecolare:396.44ICCB-19 hydrochloride
CAS:ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formula:C12H22ClN3OSPurezza:99.3%Colore e forma:SolidPeso molecolare:291.84Ref: TM-T8931L
5mg34,00€10mg50,00€25mg90,00€50mg138,00€100mg198,00€200mg296,00€500mg469,00€1mL*10mM (DMSO)34,00€Pictilisib
CAS:Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formula:C23H27N7O3S2Purezza:98.69% - 99.97%Colore e forma:SolidPeso molecolare:513.64SF1670
CAS:SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.Formula:C19H17NO3Purezza:98.25% - 98.54%Colore e forma:SolidPeso molecolare:307.34Ref: TM-T6667
1mg42,00€2mg52,00€5mg94,00€10mg118,00€25mg259,00€50mg475,00€100mg702,00€1mL*10mM (DMSO)92,00€Thiamet G
CAS:Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!Formula:C9H16N2O4SPurezza:99.06% - 99.98%Colore e forma:SolidPeso molecolare:248.3Ref: TM-T6056
2mg42,00€5mg59,00€10mg87,00€25mg178,00€50mg324,00€100mg484,00€500mg1.071,00€1mL*10mM (DMSO)59,00€Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purezza:98.83% - 99.96%Colore e forma:Less Crystalline Solid Colorless Crystalline SolidPeso molecolare:410.50Ref: TM-T2939
5mg43,00€10mg56,00€25mg86,00€50mg96,00€100mg144,00€200mg182,00€500mg306,00€1mL*10mM (DMSO)56,00€6-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurezza:98.75% - >99.99%Colore e forma:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecolare:167.19Calcineurin substrate acetate
Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.Formula:C94H154N28O31Purezza:97.59%Colore e forma:SolidPeso molecolare:2172.4Cinobufagin
CAS:Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.
Formula:C26H34O6Purezza:97.77% - 99.97%Colore e forma:SolidPeso molecolare:442.54Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormula:C23H31FO6Purezza:96.92% - 98.03%Colore e forma:Crystalline SolidPeso molecolare:422.49Vinblastine sulfate
CAS:Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).Formula:C46H58N4O9·H2SO4Purezza:97.81% - 99.82%Colore e forma:White PowderPeso molecolare:909.06Tacrolimus
CAS:Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent proteinFormula:C44H69NO12Purezza:98% - 99.94%Colore e forma:White Or Off-White Crystalline PowderPeso molecolare:804.02Ref: TM-T6S1784
1mg34,00€5mg71,00€10mg92,00€25mg148,00€50mg212,00€100mg318,00€200mg470,00€1mL*10mM (DMSO)77,00€Glycycoumarin
CAS:Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.Formula:C21H20O6Purezza:97.64% - 99.78%Colore e forma:SolidPeso molecolare:368.38Ref: TM-TN1702
1mg39,00€5mg77,00€10mg115,00€25mg222,00€50mg329,00€100mg489,00€200mg705,00€1mL*10mM (DMSO)85,00€PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Formula:C17H13Br2N5OSPurezza:99.43% - 99.887%Colore e forma:SolidPeso molecolare:495.19
