Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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Syringin
CAS:Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.Formula:C17H24O9Purezza:98.89% - 99.96%Colore e forma:SolidPeso molecolare:372.37VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.
Formula:C25H23Cl2N7O4Purezza:97.03% - 99.55%Colore e forma:SolidPeso molecolare:556.4Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formula:C50H46CaF2N2O8Purezza:98.89% - >99.99%Colore e forma:White To Off-White PowderPeso molecolare:880.98Tarenflurbil
CAS:Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.Formula:C15H13FO2Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:244.26Efavirenz
CAS:Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formula:C14H9ClF3NO2Purezza:99.2% - 99.84%Colore e forma:White To Slightly Pink Crystalline PowderPeso molecolare:315.67Ref: TM-T2393
1g383,00€5mg39,00€10mg50,00€25mg67,00€50mg85,00€100mg110,00€500mg259,00€1mL*10mM (DMSO)50,00€D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formula:C23H18N4O3Purezza:99.7% - 99.96%Colore e forma:SolidPeso molecolare:398.41Dactolisib
CAS:Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
Formula:C30H23N5OPurezza:97.64% - 99.85%Colore e forma:SolidPeso molecolare:469.54Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurezza:99.74%Colore e forma:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecolare:131.17MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formula:C24H23N5Purezza:97.35% - 99.27%Colore e forma:SolidPeso molecolare:381.47Ref: TM-T5494
1mg37,00€5mg90,00€10mg144,00€25mg289,00€50mg430,00€100mg620,00€500mg1.333,00€1mL*10mM (DMSO)108,00€Lumefantrine
CAS:Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formula:C30H32Cl3NOPurezza:98.36%Colore e forma:Yellow SolidPeso molecolare:528.94Shogaol
CAS:6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.Formula:C17H24O3Purezza:98.26% - 99.93%Colore e forma:SolidPeso molecolare:276.37Ref: TM-T6S1699
2mg40,00€5mg58,00€10mg96,00€25mg170,00€50mg268,00€100mg409,00€500mg888,00€1mL*10mM (DMSO)64,00€Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H19N5Purezza:98% - 99.77%Colore e forma:SolidPeso molecolare:329.4Irinotecan
CAS:Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formula:C33H38N4O6Purezza:98% - 99.92%Colore e forma:SolidPeso molecolare:586.68LY2109761
CAS:LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Formula:C26H27N5O2Purezza:97% - 99.83%Colore e forma:SolidPeso molecolare:441.52Ref: TM-T2123
2mg47,00€5mg70,00€10mg111,00€25mg188,00€50mg335,00€100mg507,00€200mg730,00€1mL*10mM (DMSO)77,00€trifarotene
CAS:Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.
Formula:C29H33NO4Purezza:99.51%Colore e forma:SolidPeso molecolare:459.58Melatonin
CAS:Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formula:C13H16N2O2Purezza:98% - 99.89%Colore e forma:Pale Yellow Leaflets From Benzene SolidPeso molecolare:232.28Peiminine
CAS:1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
Formula:C27H43NO3Purezza:99.52% - ≥95%Colore e forma:White PowderPeso molecolare:429.64Ridaforolimus
CAS:Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。
Formula:C53H84NO14PPurezza:90.00% - 98.55%Colore e forma:Off-White SolidPeso molecolare:990.21Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purezza:98.72% - 99.55%Colore e forma:SolidPeso molecolare:284.26Ref: TM-T6S1315
1mg37,00€5mg71,00€10mg90,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€1mL*10mM (DMSO)84,00€SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formula:C23H14ClFN2O2Purezza:99.75%Colore e forma:SolidPeso molecolare:404.82
