Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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Salubrinal
CAS:Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).Formula:C21H17Cl3N4OSPurezza:97.25% - >99.99%Colore e forma:SolidPeso molecolare:479.81Ref: TM-T3045
2mg42,00€5mg62,00€10mg93,00€25mg163,00€50mg274,00€100mg465,00€500mg1.035,00€1mL*10mM (DMSO)67,00€Vacuolin-1
CAS:Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.Formula:C26H24IN7OPurezza:97.20% - 98.45%Colore e forma:SolidPeso molecolare:577.42Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formula:C21H22O8Purezza:98.65% - 99.76%Colore e forma:SolidPeso molecolare:402.39Ref: TM-T2834
5mg57,00€10mg88,00€25mg124,00€50mg168,00€100mg265,00€200mg393,00€500mg653,00€1mL*10mM (DMSO)59,00€Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:638.82Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formula:C20H19NO3Purezza:99.83%Colore e forma:Solid CompactPeso molecolare:321.37Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:515.6UNC0638
CAS:UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.Formula:C30H47N5O2Purezza:98.88% - 99.53%Colore e forma:SolidPeso molecolare:509.73CA-5f
CAS:CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formula:C24H24N2O3Purezza:99.69%Colore e forma:SolidPeso molecolare:388.46Fangchinoline
CAS:Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:608.72AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purezza:99.87% - 99.95%Colore e forma:SolidPeso molecolare:408.45Fluvastatin
CAS:Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.Formula:C24H26FNO4Purezza:98.94%Colore e forma:SolidPeso molecolare:411.47Ketanserin tartrate
CAS:Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.Formula:C26H28FN3O9Purezza:99.68%Colore e forma:SolidPeso molecolare:545.51Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurezza:98.45%Colore e forma:SolidPeso molecolare:392.37mTOR inhibitor-8
CAS:mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for the study of non-small cell lung cancer.Formula:C24H19ClN4OSPurezza:98.11%Colore e forma:SolidPeso molecolare:446.95Ref: TM-T36316
1mg52,00€5mg111,00€10mg180,00€25mg359,00€50mg588,00€100mg944,00€1mL*10mM (DMSO)116,00€ML 145
CAS:ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)Formula:C24H22N2O5S2Purezza:97.74%Colore e forma:SolidPeso molecolare:482.57Ref: TM-T12074
1mg50,00€5mg105,00€10mg158,00€25mg264,00€50mg430,00€100mg605,00€1mL*10mM (DMSO)115,00€Doxorubicin
CAS:Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Formula:C27H29NO11Purezza:99.31%Colore e forma:Red Crystalline Solid SolidPeso molecolare:543.52Ezetimibe ketone
CAS:Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.Formula:C24H19F2NO3Purezza:99.32%Colore e forma:White Crystalline SolidPeso molecolare:407.41Chenodeoxycholic Acid sodium salt
CAS:Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.Formula:C24H39NaO4Purezza:99.68% - 99.72%Colore e forma:SolidPeso molecolare:414.55H-89
CAS:H-89 is a PKA inhibitor, a candidate cardioprotectant, induces spatial learning impairment in rats, and can be used to study myocardial infarction.Formula:C20H20BrN3O2SPurezza:98.06%Colore e forma:Off-White PowderPeso molecolare:446.36Ref: TM-T11524
5mg40,00€10mg59,00€25mg114,00€50mg170,00€100mg254,00€500mg627,00€1mL*10mM (DMSO)44,00€SB 203580 hydrochloride
CAS:SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.Formula:C21H17ClFN3OSPurezza:97.79%Colore e forma:SolidPeso molecolare:413.9
