Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formula:C26H22N2O2Purezza:97.12% - 99.96%Colore e forma:SolidPeso molecolare:394.47Ref: TM-T6671
2mg43,00€5mg58,00€10mg93,00€25mg178,00€50mg343,00€100mg509,00€500mg1.121,00€1mL*10mM (DMSO)58,00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.88%Colore e forma:SolidPeso molecolare:294.39GNE-9605
CAS:GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).Formula:C17H20ClF4N7OPurezza:98.55% - 98.75%Colore e forma:SolidPeso molecolare:449.83PX-478
CAS:PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formula:C13H20Cl4N2O3Purezza:97% - 99.79%Colore e forma:SolidPeso molecolare:394.12Ref: TM-T6961
1mg42,00€5mg88,00€10mg137,00€25mg205,00€50mg276,00€100mg434,00€200mg638,00€1mL*10mM (DMSO)88,00€Rotenone
CAS:Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formula:C23H22O6Purezza:89.58% - 99.88%Colore e forma:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecolare:394.42SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:264.12Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purezza:98.56% - 99.9%Colore e forma:Off-White SolidPeso molecolare:485.94Mycro 3
CAS:Mycro 3 is potent and selective for c-Myc in whole cell assays.Formula:C24H17ClF2N6O4Purezza:99.51% - 99.61%Colore e forma:SolidPeso molecolare:526.88Ref: TM-T4367
1mg49,00€5mg99,00€10mg168,00€25mg335,00€50mg477,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)116,00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purezza:98.81% - 99.65%Colore e forma:SolidPeso molecolare:624.77Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purezza:99.75% - 99.94%Colore e forma:SolidPeso molecolare:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purezza:99.91%Colore e forma:White To Off-White PowderPeso molecolare:290.1Wogonoside
CAS:<p>Wogonoside (Wogonin 7-O-glucuronide) acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor.</p>Formula:C22H20O11Purezza:98.24% - >99.99%Colore e forma:SolidPeso molecolare:460.39Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormula:C20H19N3O·CH4O3SPurezza:99.58% - 99.88%Colore e forma:SolidPeso molecolare:413.49Chloroquine
CAS:Chloroquine: antimalarial, anti-inflammatory, autophagy/TLRs inhibitor, treats arthritis, effective against COVID-19 in vitro. EC50: 1.13 μM.Formula:C18H26ClN3Purezza:99.5% - 99.98%Colore e forma:White To Slightly Yellow Crystalline Powder SolidPeso molecolare:319.87A-484954
CAS:A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Formula:C13H15N5O3Purezza:97.47% - 99.86%Colore e forma:SolidPeso molecolare:289.29Ref: TM-TQ0137
1mg43,00€2mg56,00€5mg88,00€10mg144,00€25mg305,00€50mg543,00€100mg775,00€1mL*10mM (DMSO)103,00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purezza:99.17% - 99.78%Colore e forma:SolidPeso molecolare:328.32Leonurine
CAS:Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.Formula:C14H21N3O5Purezza:98.55%Colore e forma:White Crystalline PowderPeso molecolare:311.33Losmapimod
CAS:Losmapimod (GSK-AHAB) (GW856553X; SB856553; GSK-AHAB) is a specific, potent, and orally active p38 MAPK inhibitor (pKi: 8.1/7.6 for p38α/β).Formula:C22H26FN3O2Purezza:98.35% - 99.89%Colore e forma:SolidPeso molecolare:383.46Ref: TM-T2277
2mg35,00€5mg52,00€10mg78,00€25mg139,00€50mg225,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)55,00€Indophagolin
CAS:Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.Formula:C19H15BrClF3N2O3SPurezza:99.76%Colore e forma:SolidPeso molecolare:523.75Ref: TM-T8946
1mg44,00€5mg87,00€10mg123,00€25mg198,00€50mg274,00€100mg386,00€200mg525,00€1mL*10mM (DMSO)90,00€Pamapimod
CAS:Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase.Formula:C19H20F2N4O4Purezza:99.52% - 99.99%Colore e forma:SolidPeso molecolare:406.38
