Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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Chloroquine dihydrochloride
CAS:Chloroquine: treats malaria, amebiasis, rheumatoid arthritis, lupus; works by inhibiting parasites in red blood cells.Formula:C18H27Cl2N3Colore e forma:SolidPeso molecolare:356.33Lamotrigine-d3
CAS:Lamotrigine-d3 is a deuterated compound of Lamotrigine. Lamotrigine has a CAS number of 84057-84-1. Lamotrigine is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity.Formula:C9D3H4Cl2N5Peso molecolare:259.11Apatinib-d8
CAS:Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM). In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.Formula:C24H15D8N5OPeso molecolare:405.52Gavilimomab
CAS:Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).Purezza:95%Colore e forma:LiquidPeso molecolare:0PBA-1105
CAS:PBA-1105, an autophagy-targeting chimeric molecule (AUTOTAC), facilitates the self-oligomerization of p62. Additionally, PBA-1105 enhances the autophagic flux of Ub-conjugated aggregates.Formula:C39H48N2O6Colore e forma:SolidPeso molecolare:640.81Erlotinib mesylate
CAS:Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.Formula:C23H27N3O7SPurezza:98%Colore e forma:SolidPeso molecolare:489.54Seriniquinone
CAS:Seriniquinone is a selective agent of anticancer that acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.Formula:C20H8O4SPurezza:98%Colore e forma:SolidPeso molecolare:344.34TAMRA alkyne, 6-isomer
CAS:<p>TAMRA alkyne, 6-isomer: a xanthene dye linker with orange emission, used for DNA/RNA labeling, reacts via Click Chemistry.</p>Formula:C28H25N3O4Colore e forma:SolidPeso molecolare:467.52Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Formula:C16H25NO4·HClPurezza:98.72% - 99.48%Colore e forma:White SolidPeso molecolare:331.15Resveratrol analog 2
CAS:Resveratrol analog 2 mimics Resveratrol, a natural antioxidant with anti-inflammatory, cardioprotective, and anticancer benefits.Formula:C16H13FO3Purezza:98%Colore e forma:SolidPeso molecolare:272.27YT-8-8
CAS:<p>YT-8-8 is a ligand for the p62-ZZ domain and can activate p62-dependent selective autophagy. This compound is also applicable in AUTOTAC design.</p>Formula:C18H23FN2O2Colore e forma:SolidPeso molecolare:318.39SU11274
CAS:SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.Formula:C28H30ClN5O4SPurezza:98.62% - 99.53%Colore e forma:Orange PowderPeso molecolare:568.09Ref: TM-T6154
1mg47,00€2mg59,00€5mg97,00€10mg150,00€25mg283,00€50mg465,00€100mg688,00€1mL*10mM (DMSO)150,00€Paroxetine hydrochloride hemihydrate
CAS:Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).Formula:C38H44Cl2F2N2O7Purezza:99.949%Colore e forma:SolidPeso molecolare:749.67SR12418
CAS:SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.Formula:C31H30FNO3Purezza:99.96%Colore e forma:SolidPeso molecolare:483.57VUF10132
CAS:<p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>Formula:C19H13BrCl4N2O2Purezza:98%Colore e forma:SolidPeso molecolare:523.03IZCZ-3
CAS:IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.Formula:C46H49N7OPurezza:98%Colore e forma:SolidPeso molecolare:715.93(R)-Hydroxychloroquine
CAS:(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.Formula:C18H26ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:335.87AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formula:C21H21F3N4OPurezza:99.55% - 99.89%Colore e forma:SolidPeso molecolare:402.41Ref: TM-T10277
1mg70,00€5mg145,00€10mg207,00€25mg348,00€50mg495,00€100mg678,00€500mgPrezzo su richiestaLS2265
CAS:LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.Formula:C19H20ClNO6SPurezza:98%Colore e forma:SolidPeso molecolare:425.88AGN 205327
CAS:AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.Formula:C24H26N2O3Purezza:99.45% - 99.71%Colore e forma:SolidPeso molecolare:390.47
