Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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YOK-2204
CAS:YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.Formula:C28H35NO4Colore e forma:SolidPeso molecolare:449.58OSU-53
CAS:OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.Formula:C25H24F3N3O6S2Colore e forma:SolidPeso molecolare:583.6YM-155 hydrochloride
CAS:Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Formula:C20H19ClN4O3Colore e forma:SolidPeso molecolare:398.85ATG7-IN-3
CAS:ATG7-IN-3 (Compound 18) is an effective ATG7 inhibitor (IC₅₀ = 48 nM), suppressing autophagy, suitable for research into gliomas and colorectal cancers.Formula:C11H16N6O5S2Purezza:99.74% - 99.88%Colore e forma:SolidPeso molecolare:376.41Ref: TM-T61552
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mg1.388,00€50mg1.872,00€100mg2.527,00€Evogliptin
CAS:Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.Formula:C19H26F3N3O3Colore e forma:SolidPeso molecolare:401.42IT1t
CAS:IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.Formula:C21H34N4S2Purezza:98%Colore e forma:SolidPeso molecolare:406.65(Rac)-BL-918
CAS:(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.Formula:C23H15F8N3OSPurezza:97.03%Colore e forma:SolidPeso molecolare:533.44Ref: TM-T12662
1mg47,00€5mg87,00€10mg133,00€25mg263,00€50mg455,00€100mg747,00€200mg1.017,00€1mL*10mM (DMSO)97,00€MPM-1
MPM-1, a marine mimic, induces rapid necrotic-like death in cancer cells, disrupts autophagy, and causes lysosomal swelling.Formula:C34H44F6N4O7Colore e forma:SolidPeso molecolare:734.73PX20606 trans racemate
CAS:PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).Formula:C29H22Cl3NO4Purezza:98%Colore e forma:SolidPeso molecolare:554.85MRT-68601 HCl
CAS:MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.Formula:C25H34N6O2Purezza:98%Colore e forma:SolidPeso molecolare:450.58Autophagy inducer 4
CAS:Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration & is 76x more toxic to T47D cells.Formula:C32H37NO6Colore e forma:SolidPeso molecolare:531.64eIF4A3-IN-2
CAS:eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.Formula:C25H19Br2ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:602.71KRH-1636
CAS:KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.Formula:C32H37N7O2Colore e forma:SolidPeso molecolare:551.68(S)-Hydroxychloroquine
CAS:(S)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine shows efficiently inhibits SARS-CoV-2 infection in vitro.Formula:C18H26ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:335.87TUN-92046
CAS:TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.Formula:C7H10O5Purezza:95.48% - 98.58%Colore e forma:SolidPeso molecolare:174.15TN-14003
CAS:TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.Formula:C90H141N33O18S2Colore e forma:SolidPeso molecolare:2037.42VUF5834
CAS:VUF5834 is a full inverse agonist of CXCR3 N3.35A.Formula:C31H41N5O2Purezza:98%Colore e forma:SolidPeso molecolare:515.69SX-517
CAS:SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.Formula:C19H16BFN2O3SColore e forma:SolidPeso molecolare:382.22SA72
CAS:SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).Formula:C21H26N2O6Purezza:98%Colore e forma:SolidPeso molecolare:402.44rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purezza:99.6%Colore e forma:SolidPeso molecolare:605.58
