Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1488 prodotti di "Autofagia"
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Atg4B-IN-2
CAS:<p>Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.</p>Formula:C21H30O3Purezza:98.86%Colore e forma:SolidPeso molecolare:330.46CP-312
CAS:<p>CP-312 activates antioxidant defense, induces HMOX1, and shields human iPSC-derived cardiomyocytes from oxidative stress.</p>Formula:C16H12ClN3OS2Purezza:99.61%Colore e forma:SolidPeso molecolare:361.87MAPK13-IN-1
CAS:MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).Formula:C20H23N5O2Purezza:99.62%Colore e forma:SolidPeso molecolare:365.43AZD8797
CAS:AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.Formula:C19H25N5OS2Purezza:98.73% - 99.68%Colore e forma:SolidPeso molecolare:403.56Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purezza:99.53% - 99.78%Colore e forma:SolidPeso molecolare:767.86IT1t dihydrochloride
CAS:IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.Formula:C21H36Cl2N4S2Purezza:99.91%Colore e forma:SolidPeso molecolare:479.57Acetazolamide sodium
CAS:Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.Formula:C4H5N4NaO3S2Purezza:99.71% - 99.87%Colore e forma:SolidPeso molecolare:244.23Cysmethynil
CAS:Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 phase, and can be used for the study of solid tumors.Formula:C25H32N2OPurezza:99%Colore e forma:SolidPeso molecolare:376.53LRRK2-IN-7
CAS:LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Formula:C24H26N6OPurezza:99.26%Colore e forma:SolidPeso molecolare:414.5Ezurpimtrostat hydrochloride
CAS:Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.Formula:C25H32Cl2N4Purezza:99.84%Colore e forma:SolidPeso molecolare:459.45FMK 9a
CAS:FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formula:C23H21FN2O3Purezza:98.97%Colore e forma:SolidPeso molecolare:392.42Laduviglusib trihydrochloride
CAS:Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.Formula:C22H20Cl5N8Purezza:99.34%Colore e forma:SolidPeso molecolare:573.71Cytarabine hydrochloride
CAS:<p>Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase.</p>Formula:C9H14ClN3O5Purezza:98.46%Colore e forma:White PowderPeso molecolare:279.68NUCC-390
CAS:NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.Formula:C23H33N5OPurezza:97.08%Colore e forma:SolidPeso molecolare:395.54CCT020312
CAS:CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.Formula:C31H30Br2N4O2Purezza:98.63%Colore e forma:SolidPeso molecolare:650.4Tin-protoporphyrin IX dichloride
CAS:Tin-protoporphyrin IX inhibits HO-1, enhancing chemo efficacy in mouse PDAC.Formula:C34H32Cl2N4O4SnPurezza:98%Colore e forma:SolidPeso molecolare:750.26Rosolutamide
CAS:Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formula:C28H32O6Purezza:95.48% - 99.15%Colore e forma:SolidPeso molecolare:464.55AC-73
CAS:<p>AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.</p>Formula:C21H21NO2Purezza:98.95%Colore e forma:SolidPeso molecolare:319.4Mavorixafor
CAS:<p>Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.</p>Formula:C21H27N5Purezza:98.56%Colore e forma:SolidPeso molecolare:349.47XRK3F2
CAS:XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.Formula:C23H24ClF2NO3Purezza:98.91% - 99.12%Colore e forma:SolidPeso molecolare:435.89
