Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1483 prodotti di "Autofagia"
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SR10067
CAS:SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Formula:C31H31NO3Purezza:99.57%Colore e forma:SolidPeso molecolare:465.58Acitretin sodium
CAS:Acitretin sodium is a second-generation, systemic retinoid. It is also has been used in the treatment of psoriasis.Formula:C21H26NaO3Purezza:98%Colore e forma:SolidPeso molecolare:349.42AGN 194310
CAS:AGN 194310 (VTP-194310) is retinioic acid receptors (RARs) pan-antagonist. The Kd values of 3 nM, 2 nM, 5 nM for RARα, RARβ, RARγ, respectively[1][2].Formula:C28H24O2SColore e forma:SolidPeso molecolare:424.554E2RCat
CAS:<p>4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expression</p>Formula:C22H14ClNO4S2Purezza:98.44%Colore e forma:SolidPeso molecolare:455.93Pentixafor
CAS:<p>Pentixafor is a peptide that selectively targets the CXCR4 receptor and can be labeled with Gallium-68 (68Ga) for visualization using positron emission</p>Formula:C60H80N14O14Purezza:98%Colore e forma:SolidPeso molecolare:1221.36Beclin1-ATG14L interaction inhibitor 1
CAS:Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L.Formula:C23H24N4O5SPurezza:98%Colore e forma:SolidPeso molecolare:468.53INT-767
CAS:INT-767 is a highly potent farneson X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral fat brown lipogenesis and mitochondrial functionFormula:C25H43NaO6SPurezza:98%Colore e forma:SolidPeso molecolare:494.66AGN 194078
CAS:AGN 194078 is a selective RARα agonist (Kd: 3 nM; EC50: 112 nM).Formula:C22H23F2NO4Colore e forma:SolidPeso molecolare:403.42BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purezza:97.67% - 98.86%Colore e forma:SolidPeso molecolare:548.34CC214-1
CAS:CC214-1 is an mTOR inhibitor that inhibits protein translation, induces autophagy, and is an in vitro tool compound for exploring the biology of mTOR kinases.Formula:C20H21N7O2Purezza:97.16%Colore e forma:SolidPeso molecolare:391.43Calmidazolium chloride
CAS:Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formula:C31H23Cl7N2OPurezza:98.53%Colore e forma:SolidPeso molecolare:687.7(3R,5R)-Rosuvastatin
CAS:<p>(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).</p>Formula:C22H28FN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:481.54NUCC-390 dihydrochloride (1060524-97-1 free base)
NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.Formula:C23H35Cl2N5OPurezza:98%Colore e forma:SolidPeso molecolare:468.46AEW541 HCl
CAS:AEW541 (CAS# 475489-16-8) is a selective IGF-IR kinase inhibitor (IC50: IGF-IR=0.086μM, InsR=2.3μM), blocking IGF-I effects and colony formation.Formula:C27H31Cl2N5OColore e forma:SolidPeso molecolare:512.47EACC
CAS:<p>EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.</p>Formula:C13H11N3O6S2Purezza:99.8%Colore e forma:SolidPeso molecolare:369.37Di-N-desethyl amiodarone hydrochloride
CAS:Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formula:C21H22ClI2NO3Purezza:98%Colore e forma:SolidPeso molecolare:625.67AMD-3329 free base
CAS:AMD-3329 is a potent anti-HIV agent that blocks virus replication by targeting CXCR4, a key receptor for X4 viruses' entry.Formula:C34H50N8Colore e forma:SolidPeso molecolare:570.81CXCR4 antagonist 6
CAS:CXCR4 antagonist 6 blocks CXCR4 (IC50: 79 nM), hinders calcium flux (IC50: 0.25 nM), reduces cell migration, and is effective in cancer metastasis mice.Formula:C21H30N6Colore e forma:SolidPeso molecolare:366.5DCAP
CAS:DCAP, a broad-spectrum antibiotic, disrupts the membranes of both Gram-positive and Gram-negative bacteria. Additionally, it inhibits late-stage autophagy by blocking autophagolysosome maturation and interrupting autophagic flux [1].Formula:C19H22Cl2N2O4Colore e forma:SolidPeso molecolare:413.3ATG12-ATG3 inhibitor 1
CAS:ATG12-ATG3 Inhibitor 1 (compound 189) serves as a potent inhibitor of autophagy [1].Formula:C18H17NO3SColore e forma:SolidPeso molecolare:327.4
