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Recettore dell'endotelina

Recettore dell'endotelina

I recettori dell'endotelina sono GPCR che mediano gli effetti delle endoteline, potenti peptidi vasocostrittori che giocano un ruolo significativo nella regolazione del tono vascolare, nel controllo della pressione sanguigna e nella proliferazione cellulare. Gli antagonisti dei recettori dell'endotelina sono utilizzati nel trattamento di condizioni come l'ipertensione arteriosa polmonare e l'insufficienza cardiaca. Questi recettori sono anche importanti bersagli nella ricerca sulle malattie cardiovascolari e sul cancro. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori dell'endotelina di alta qualità per supportare la tua ricerca in biologia cardiovascolare, oncologia e fisiologia vascolare.

Trovati 86 prodotti di "Recettore dell'endotelina"

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  • Sulfisoxazole

    CAS:
    Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.
    Formula:C11H13N3O3S
    Purezza:99.87% - 99.98%
    Colore e forma:White To Cream Powder
    Peso molecolare:267.30

    Ref: TM-T0750

    1g
    74,00€
    200mg
    37,00€
    500mg
    52,00€
    1mL*10mM (DMSO)
    34,00€
  • Enrasentan

    CAS:
    Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure and protects myocardial function.
    Formula:C29H30O8
    Purezza:97.9% - 98.39%
    Colore e forma:Solid
    Peso molecolare:506.54

    Ref: TM-T31640

    1mg
    185,00€
    5mg
    459,00€
    10mg
    657,00€
    25mg
    1.031,00€
  • Atrial Natriuretic Peptide (ANP) (1-28), rat

    CAS:
    Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
    Formula:C128H205N45O39S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3062.41

    Ref: TM-TP1221

    1mg
    1.454,00€
  • Atrial natriuretic factor (1-28) (rat) TFA


    ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.
    Formula:C130H206N45F3O41S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3176.43

    Ref: TM-TP1218

    1mg
    217,00€
    5mg
    770,00€
  • ACT-373898

    CAS:
    <p>ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1</p>
    Formula:C15H17BrN4O5S
    Colore e forma:Solid
    Peso molecolare:445.29

    Ref: TM-T35623

    1mg
    92,00€
    5mg
    275,00€
    10mg
    464,00€
    25mg
    944,00€
  • IRL-1038

    CAS:
    <p>ETB endothelin receptor antagonist</p>
    Formula:C68H92N14O15S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1409.67

    Ref: TM-TP2262

    1mg
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    100mg
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    500mg
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  • [Ala1,3,11,15]-Endothelin

    CAS:
    Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
    Formula:C109H163N25O32S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2368

    Ref: TM-TP2099

    5mg
    477,00€
  • Nebentan

    CAS:
    <p>Nebentan (YM598) is an oral, selective ETA antagonist; Ki: 0.697 nM (ETA), 569 nM (ETB); may slow cor pulmonale, myocardial infarction.</p>
    Formula:C24H21N5O5S
    Colore e forma:Solid
    Peso molecolare:491.52

    Ref: TM-T36007

    5mg
    187,00€
    10mg
    315,00€
    25mg
    552,00€
  • SB234551

    CAS:
    SB234551 is a selective antagonist of endothelin ETA receptor.
    Formula:C34H34N2O9
    Colore e forma:Solid
    Peso molecolare:614.64

    Ref: TM-T28683

    25mg
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    50mg
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    100mg
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  • IRL-3630

    CAS:
    IRL 3460 is an enantiomer.
    Formula:C31H40N4O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:596.74

    Ref: TM-T25541

    25mg
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    50mg
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    100mg
    Prezzo su richiesta
  • Sarafotoxin S6b

    CAS:
    non-selective endothelin receptor agonist
    Formula:C110H163N27O34S5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2567.96

    Ref: TM-TP2290

    1mg
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    100mg
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    500mg
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  • Sarafotoxin S6c

    CAS:
    Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).
    Formula:C103H147N27O37S5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2516

    Ref: TM-TP2120

    100µg
    888,00€
  • PD 142893

    CAS:
    PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.
    Formula:C50H65N7O10
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:924.09

    Ref: TM-T25922

    25mg
    1.444,00€
  • IRL-1620

    CAS:
    IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).
    Formula:C86H117N17O27
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1820.974

    Ref: TM-T15595

    500µg
    909,00€
  • Sarafotoxin S6a

    CAS:
    Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
    Formula:C105H156N28O34S5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2514.85

    Ref: TM-TP2119

    1mg
    512,00€
  • BQ-123 TFA


    BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.
    Formula:C33H43F3N6O9
    Colore e forma:Solid
    Peso molecolare:724.72

    Ref: TM-T73877

    5mg
    Prezzo su richiesta
    50mg
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  • [Ala2] Endothelin-3, human

    CAS:
    [Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.
    Formula:C120H166N26O32S4
    Colore e forma:Solid
    Peso molecolare:2613.02

    Ref: TM-T76305

    5mg
    Prezzo su richiesta
    50mg
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  • Endothelin 1 (swine, human), Alexa Fluor 488-labeled


    Synthetic human/swine Endothelin 1 peptide, tagged with Alexa Fluor 488, acts as a strong vasoconstrictor via ET A/B receptors.
    Colore e forma:Solid
    Peso molecolare:2848.4

    Ref: TM-T76081

    5mg
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    50mg
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  • [Lys4] Sarafotoxin S6c

    CAS:
    [Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.
    Formula:C105H153N27O36S5
    Colore e forma:Solid
    Peso molecolare:2529.82

    Ref: TM-T76302

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Endothelin-2 (49-69), human TFA


    Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
    Formula:C117H161N26F3O34S4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2660.94

    Ref: TM-TP2143

    100mg
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    500mg
    Prezzo su richiesta
  • Methylsolfonyl 25(S)-Δ7-dafachronic acid


    Methylsulfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with an IC50 value of 0.41 μM. It exhibits low cytotoxicity in HepG2 cells, with an IC50 value greater than 200 μM. Methylsulfonyl 25(S)-Δ7-dafachronic acid is applicable in the study of parasitic diseases.
    Formula:C28H45NO4S
    Peso molecolare:491.30693

    Ref: TM-T209317

    10mg
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    50mg
    Prezzo su richiesta
  • Endothelin 1 (swine, human) (TFA)

    CAS:
    Synthetic human/swine Endothelin 1 (TFA) peptide; a potent vasoconstrictor acting on ET A and ET B receptors.
    Formula:C111H160F3N25O34S5
    Peso molecolare:2605.93

    Ref: TM-T75731

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Bosentan-d4

    CAS:
    Bosentan-d4: deuterium version of Bosentan, competitive ET A/B antagonist, Ki: 4.7nM (ET A), 95nM (ET B) in human SMC.
    Formula:C27H25D4N5O6S
    Peso molecolare:555.64

    Ref: TM-T73820

    5mg
    948,00€
  • ANP (1-30), frog

    CAS:
    ANP (1-30), frog, a peptide fragment sourced from atrial natriuretic peptide of frog origin, exhibits natriuretic, diuretic, and vasorelaxant properties.
    Formula:C131H217N49O41S4
    Peso molecolare:3262.69

    Ref: TM-T76386

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Big endothelin-1 (rat 1-39)

    CAS:
    Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure in

    Ref: TM-T82886

    5mg
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    50mg
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  • [Asn18] Endothelin-1, human

    CAS:
    [Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].
    Formula:C109H164N26O31S5
    Peso molecolare:2494.96

    Ref: TM-T76329

    5mg
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    50mg
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  • Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

    CAS:
    Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.
    Formula:C129H207N45O41S3
    Purezza:99.78%
    Colore e forma:Soild
    Peso molecolare:3140.5

    Ref: TM-TP1219

    1mg
    185,00€
    5mg
    459,00€
    10mg
    657,00€
    25mg
    1.026,00€
    50mg
    1.388,00€
    100mg
    1.872,00€
    200mg
    2.527,00€
  • IRL-1038 acetate


    IRL-1038 acetate is a potent ETB endothelin receptor antagonist.
    Formula:C70H96N14O17S2
    Purezza:97.51%
    Colore e forma:Soild
    Peso molecolare:1469.73

    Ref: TM-TP2262L

    1mg
    409,00€
    5mg
    947,00€
    10mg
    1.415,00€
    25mg
    2.422,00€
    50mg
    3.258,00€
  • IRL-1038 TFA


    IRL-1038 TFA is an ETB receptor antagonist used in the study of cardiovascular disease.
    Formula:C70H93F3N14O17S2
    Purezza:98.79%
    Colore e forma:Solid
    Peso molecolare:1523.7

    Ref: TM-TP2262L1

    1mg
    38,00€
    5mg
    59,00€
    10mg
    83,00€
  • IRL-1620 acetate


    IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
    Formula:C88H121N17O29
    Purezza:96.64%
    Colore e forma:Solid
    Peso molecolare:1881

    Ref: TM-T15595L

    1mg
    180,00€
    5mg
    445,00€
    10mg
    652,00€
    25mg
    1.026,00€
    50mg
    1.378,00€
    100mg
    1.863,00€
  • Atrial natriuretic peptide (3-28) (human)

    CAS:
    Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation of
    Formula:C118H187N43O36S3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2880.21

    Ref: TM-T80438

    5mg
    Prezzo su richiesta
    50mg
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  • Sulfatroxazole

    CAS:
    Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.
    Formula:C11H13N3O3S
    Colore e forma:Solid
    Peso molecolare:267.3

    Ref: TM-T203689

    10mg
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    50mg
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  • BQ-3020 ammonium


    BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2
    Formula:C96H140N20O25S·xNH3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2006.32 (free base)

    Ref: TM-T78096

    5mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Endothelin-3 (Rat,Human) (TFA)


    Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).
    Formula:C123H169F3N26O35S4·xC2HF3O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2757.07 (free base)

    Ref: TM-TP1173

    1mg
    567,00€
  • Sitaxsentan sodium

    CAS:
    Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.
    Formula:C18H14ClN2O6S2·Na
    Purezza:98.39% - 99.01%
    Colore e forma:Solid
    Peso molecolare:476.89

    Ref: TM-T6672

    5mg
    35,00€
    10mg
    58,00€
    25mg
    101,00€
    50mg
    170,00€
    100mg
    273,00€
    200mg
    398,00€
    1mL*10mM (DMSO)
    38,00€
  • Bosentan

    CAS:
    Bosentan is a competitive endothelin receptor antagonist, used for treating pulmonary arterial hypertension.
    Formula:C27H29N5O6S
    Purezza:99.74% - 99.84%
    Colore e forma:Pale Yellow To Off-White Solid
    Peso molecolare:551.614

    Ref: TM-T6264

    10mg
    38,00€
    25mg
    56,00€
    50mg
    81,00€
    100mg
    127,00€
    200mg
    207,00€
    500mg
    310,00€
    1mL*10mM (DMSO)
    88,00€
  • Darusentan

    CAS:
    Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteries
    Formula:C22H22N2O6
    Purezza:98.72%
    Colore e forma:Solid
    Peso molecolare:410.43

    Ref: TM-T5458

    2mg
    46,00€
    5mg
    69,00€
    10mg
    105,00€
    25mg
    183,00€
    50mg
    304,00€
    100mg
    437,00€
    200mg
    615,00€
    1mL*10mM (DMSO)
    71,00€
  • BQ-123

    CAS:
    BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
    Formula:C31H42N6O7
    Purezza:99.22% - ≥95%
    Colore e forma:Solid
    Peso molecolare:610.7

    Ref: TM-T6792

    1mg
    88,00€
    5mg
    202,00€
    10mg
    329,00€
    25mg
    548,00€
    50mg
    782,00€
    100mg
    1.035,00€
    1mL*10mM (DMSO)
    274,00€
  • Ambrisentan sodium

    CAS:
    Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).
    Formula:C22H21N2NaO4
    Colore e forma:Solid
    Peso molecolare:400.41

    Ref: TM-T61921

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • BQ-788 sodium salt

    CAS:
    BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).
    Formula:C34H51N5NaO7
    Colore e forma:Solid
    Peso molecolare:664.8

    Ref: TM-T10595L

    2mg
    270,00€
    25mg
    929,00€
    50mg
    1.206,00€
    100mg
    1.833,00€
  • Atrasentan sodium

    CAS:
    Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.
    Formula:C29H37N2NaO6
    Colore e forma:Solid
    Peso molecolare:532.61

    Ref: TM-T70198

    25mg
    1.586,00€
    50mg
    2.072,00€
    100mg
    2.660,00€
  • Ro 46-2005

    CAS:
    Ro 46-2005: Synthetic non-peptide, blocks 125I-ET-1 at ETA receptors on human vascular cells (IC50: 220 nM).
    Formula:C23H27N3O6S
    Purezza:98.02% - 98.8%
    Colore e forma:Solid
    Peso molecolare:473.54

    Ref: TM-T3194

    5mg
    46,00€
    10mg
    80,00€
    25mg
    131,00€
    50mg
    212,00€
    100mg
    304,00€
    200mg
    437,00€
    1mL*10mM (DMSO)
    49,00€
  • RO 46-8443

    CAS:
    RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.
    Formula:C31H35N3O8S
    Purezza:98.77% - 99.77%
    Colore e forma:Solid
    Peso molecolare:609.69

    Ref: TM-T3474

    1mg
    40,00€
    2mg
    52,00€
    5mg
    88,00€
    10mg
    126,00€
    25mg
    250,00€
    50mg
    354,00€
    100mg
    522,00€
    500mg
    1.111,00€
  • Bosentan (hydrate)

    CAS:
    Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
    Formula:C27H29N5O6S·H2O
    Purezza:99.31% - 99.86%
    Colore e forma:White Powder
    Peso molecolare:569.63

    Ref: TM-T6265

    25mg
    47,00€
    50mg
    60,00€
    100mg
    96,00€
    1mL*10mM (DMSO)
    64,00€
  • Ambrisentan

    CAS:
    Ambrisentan, an endothelin antagonist for PAH, has a low risk of liver enzyme elevation, not linked to acute liver injury.
    Formula:C22H22N2O4
    Purezza:99.65% - 99.86%
    Colore e forma:Solid
    Peso molecolare:378.42

    Ref: TM-T1655

    5mg
    35,00€
    10mg
    46,00€
    25mg
    77,00€
    50mg
    105,00€
    100mg
    157,00€
    200mg
    224,00€
    1mL*10mM (DMSO)
    42,00€
  • Atrasentan

    CAS:
    Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and quality-assured.
    Formula:C29H38N2O6
    Purezza:97.65% - 99.08%
    Colore e forma:Solid
    Peso molecolare:510.62

    Ref: TM-TQ0259

    1mg
    48,00€
    5mg
    96,00€
    10mg
    137,00€
    25mg
    264,00€
    50mg
    376,00€
    100mg
    612,00€
    200mg
    842,00€
    1mL*10mM (DMSO)
    115,00€
  • Aprocitentan

    CAS:
    Aprocitentan (ACT-132577) is ETA and ETB antagonist .
    Formula:C16H14Br2N6O4S
    Purezza:99.17%
    Colore e forma:Solid
    Peso molecolare:546.19

    Ref: TM-T7817

    1mg
    58,00€
    5mg
    116,00€
    10mg
    170,00€
    25mg
    311,00€
    50mg
    439,00€
    100mg
    655,00€
    200mg
    887,00€
    1mL*10mM (DMSO)
    142,00€
  • Sparsentan

    CAS:
    Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,
    Formula:C32H40N4O5S
    Purezza:97.94% - 98.69%
    Colore e forma:Solid
    Peso molecolare:592.75

    Ref: TM-T5355

    2mg
    39,00€
    5mg
    58,00€
    10mg
    94,00€
    25mg
    170,00€
    50mg
    259,00€
    100mg
    380,00€
    200mg
    540,00€
    1mL*10mM (DMSO)
    77,00€
  • BMS 182874 hydrochloride

    CAS:
    BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.
    Formula:C17H20ClN3O3S
    Purezza:97.01%
    Colore e forma:Solid
    Peso molecolare:381.88

    Ref: TM-T21790

    1mg
    81,00€
    2mg
    97,00€
    5mg
    148,00€
    10mg
    215,00€
    25mg
    361,00€
    50mg
    505,00€
    100mg
    702,00€
    200mg
    947,00€
    1mL*10mM (DMSO)
    155,00€
  • ANP(1-28) Acetate (human, porcine)

    CAS:
    <p>Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.</p>
    Formula:C129H207N45O41S3
    Purezza:98.24%
    Colore e forma:Solid
    Peso molecolare:3140.5

    Ref: TM-TP1220L

    1mg
    185,00€
    5mg
    459,00€
    10mg
    657,00€
    25mg
    1.026,00€
    50mg
    1.388,00€
    100mg
    1.872,00€
    200mg
    2.527,00€
  • Macitentan

    CAS:
    Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).
    Formula:C19H20Br2N6O4S
    Purezza:98% - >99.99%
    Colore e forma:Solid
    Peso molecolare:588.27

    Ref: TM-T2561

    10mg
    44,00€
    25mg
    52,00€
    50mg
    56,00€
    100mg
    84,00€
    500mg
    170,00€
    1mL*10mM (DMSO)
    40,00€
  • Endothelin-2 (49-69), human

    CAS:
    Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
    Formula:C115H160N26O32S4
    Purezza:98.26%
    Colore e forma:Solid
    Peso molecolare:2546.92

    Ref: TM-TP1174

    1mg
    188,00€
    5mg
    405,00€
    10mg
    562,00€
    25mg
    843,00€
    50mg
    Prezzo su richiesta
  • Nebentan potassium

    CAS:
    Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.
    Formula:C24H20KN5O5S
    Purezza:99.05%
    Colore e forma:Solid
    Peso molecolare:529.61

    Ref: TM-T36008

    1mg
    55,00€
    2mg
    81,00€
    5mg
    117,00€
    10mg
    187,00€
    25mg
    329,00€
    50mg
    530,00€
    100mg
    718,00€
    200mg
    938,00€
    1mL*10mM (DMSO)
    140,00€
  • Zibotentan

    CAS:
    Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
    Formula:C19H16N6O4S
    Purezza:97.00% - 97.02%
    Colore e forma:Solid
    Peso molecolare:424.43

    Ref: TM-T6258

    1mg
    43,00€
    2mg
    57,00€
    5mg
    92,00€
    10mg
    144,00€
    25mg
    283,00€
    50mg
    Prezzo su richiesta
    1mL*10mM (DMSO)
    93,00€
  • TBC3711

    CAS:
    TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.
    Formula:C20H21N3O5S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:447.53

    Ref: TM-T15232

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • ZD-1611

    CAS:
    ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.
    Formula:C22H24N4O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:456.51

    Ref: TM-T17287

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • CH 141

    CAS:
    CH 141 is a new type of peripheral vasodilator.
    Formula:C19H21N3O
    Colore e forma:Solid
    Peso molecolare:307.39

    Ref: TM-T30859

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • ABT-546

    CAS:
    ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.
    Formula:C30H48N2O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:532.71

    Ref: TM-T10225

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • BMS-193884

    CAS:
    BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.
    Formula:C20H17N3O4S
    Colore e forma:Solid
    Peso molecolare:395.43

    Ref: TM-T30501

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • CI 1020

    CAS:
    endothelin-A receptor (ETA) antagonist
    Formula:C28H26O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:506.5

    Ref: TM-T22663

    25mg
    1.586,00€
    50mg
    2.072,00€
    100mg
    2.660,00€
  • PD-156707

    CAS:
    PD-156707 is a selective antagonist of endothelin A receptor.
    Formula:C28H26NaO9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:529.497

    Ref: TM-T28343

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • WS 009B

    CAS:
    WS 009B is an antagonist of the endothelin receptor.
    Formula:C24H25NO11S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:535.52

    Ref: TM-T24081

    25mg
    1.444,00€
  • Daglutril

    CAS:
    Daglutril is a NEP/ECE inhibitor for treating hypertension, heart failure, and pulmonary issues, blocking big endothelin-1 conversion.
    Formula:C31H38N2O6
    Colore e forma:Solid
    Peso molecolare:534.64

    Ref: TM-T27119

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • Atrasentan hydrochloride

    CAS:
    Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).
    Formula:C29H39ClN2O6
    Purezza:99.75%
    Colore e forma:Solid
    Peso molecolare:547.08

    Ref: TM-TQ0270

    1mg
    49,00€
    5mg
    97,00€
    10mg
    137,00€
    25mg
    264,00€
    50mg
    376,00€
    1mL*10mM (DMSO)
    116,00€
  • Avosentan

    CAS:
    <p>Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.</p>
    Formula:C23H21N5O5S
    Purezza:98.31% - 99.47%
    Colore e forma:Solid
    Peso molecolare:479.51

    Ref: TM-TQ0282

    1mg
    40,00€
    5mg
    85,00€
    10mg
    106,00€
    25mg
    216,00€
    50mg
    376,00€
    100mg
    550,00€
  • PD-159020

    CAS:
    PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).
    Formula:C32H25NO8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:551.54

    Ref: TM-T12382

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • WS 009A

    CAS:
    WS 009A is an antagonist of the endothelin receptor.
    Formula:C24H25NO10S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:519.52

    Ref: TM-T24053

    25mg
    1.444,00€
  • ETA antagonist 1

    CAS:
    ETA antagonist 1 is an antagonist of ETA selective (IC50 of 0.08 μM).
    Formula:C20H25N3O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:387.5

    Ref: TM-T12157

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • Aminaftone

    CAS:
    Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.
    Formula:C18H15NO4
    Purezza:96.31% - 99.39%
    Colore e forma:Solid
    Peso molecolare:309.32

    Ref: TM-T14219

    1mg
    200,00€
    5mg
    552,00€
    10mg
    685,00€
    25mg
    905,00€
  • FR 139317

    CAS:
    highly potent and selective ETA endothelin receptor antagonist
    Formula:C33H44N6O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:604.74

    Ref: TM-T22791

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • BMS 182874

    CAS:
    BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.
    Formula:C17H19N3O3S
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:345.42

    Ref: TM-T26841

    1mg
    35,00€
    5mg
    74,00€
    10mg
    109,00€
    25mg
    182,00€
    50mg
    259,00€
    100mg
    356,00€
    200mg
    490,00€
  • Edonentan

    CAS:
    Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.
    Formula:C28H32N4O5S
    Purezza:98.07% - 99.6%
    Colore e forma:Solid
    Peso molecolare:536.64

    Ref: TM-T31605

    1mg
    563,00€
    5mg
    1.121,00€
    10mg
    1.254,00€
    25mg
    1.434,00€
  • SB-209670

    CAS:
    SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.
    Formula:C29H28O9
    Purezza:98.29% - 99.40%
    Colore e forma:Solid
    Peso molecolare:520.53

    Ref: TM-T34541

    1mg
    333,00€
    5mg
    787,00€
    10mg
    1.074,00€
    25mg
    1.510,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
    500mg
    4.655,00€
    1mL*10mM (DMSO)
    797,00€
  • Sitaxsentan

    CAS:
    Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.
    Formula:C18H15ClN2O6S2
    Purezza:97.99% - 98.71%
    Colore e forma:Solid
    Peso molecolare:454.9

    Ref: TM-T12924

    1mg
    285,00€
    5mg
    740,00€
    10mg
    950,00€
    25mg
    1.235,00€
    50mg
    1.520,00€
    100mg
    1.900,00€
    500mg
    3.800,00€
  • L-749329

    CAS:
    L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.
    Formula:C28H29NO8S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:539.6

    Ref: TM-T27776

    25mg
    1.872,00€
    50mg
    2.452,00€
    100mg
    3.230,00€
  • Clazosentan

    CAS:
    Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.
    Formula:C25H23N9O6S
    Purezza:95.39% - >99.99%
    Colore e forma:Solid
    Peso molecolare:577.57

    Ref: TM-T64084

    1mg
    79,00€
    5mg
    178,00€
    10mg
    279,00€
    25mg
    628,00€
    50mg
    1.017,00€
    100mg
    1.311,00€
    200mg
    1.768,00€
    1mL*10mM (DMSO)
    230,00€
  • K-8794

    CAS:
    <p>K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.</p>
    Formula:C36H38N6O6S
    Colore e forma:Solid
    Peso molecolare:682.789

    Ref: TM-T204123

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Edonentan hydrate

    CAS:
    Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].
    Formula:C28H34N4O6S
    Peso molecolare:554.66

    Ref: TM-T86338

    25mg
    1.784,00€
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • Diosuxentan

    CAS:
    Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.
    Formula:C20H21BrN6O7S
    Colore e forma:Solid
    Peso molecolare:569.39

    Ref: TM-T211846

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • BMS-248360

    CAS:
    BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.
    Formula:C36H45N5O5S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:659.84

    Ref: TM-T14672

    25mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • JKC 302

    CAS:
    JKC 302 is an ET-A receptor antagonist that partially inhibits the contraction of tracheal rings in asthmatic rats induced by ET-1.
    Formula:C30H42N6O6
    Colore e forma:Solid
    Peso molecolare:582.69

    Ref: TM-TP3818

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Macitentan (n-butyl analogue)

    CAS:
    Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.
    Formula:C20H21Br2N5O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:587.29

    Ref: TM-T11935

    25mg
    1.730,00€
    50mg
    2.262,00€
    100mg
    2.945,00€
  • IRL 2500

    CAS:
    IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.
    Formula:C36H35N3O4
    Purezza:99.36%
    Colore e forma:White Crystalline Solid
    Peso molecolare:573.68

    Ref: TM-T15596

    2mg
    44,00€
    5mg
    64,00€
    10mg
    93,00€
    25mg
    180,00€
    50mg
    264,00€
    100mg
    369,00€
    1mL*10mM (DMSO)
    78,00€
  • Tezosentan

    CAS:
    Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).
    Formula:C27H27N9O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:605.63

    Ref: TM-T17064

    25mg
    2.137,00€
    50mg
    2.888,00€
    100mg
    3.763,00€
  • BQ-788

    CAS:
    BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.
    Formula:C34H51N5O7
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:641.8

    Ref: TM-T10595

    1mg
    137,00€
    2mg
    188,00€
    5mg
    329,00€
    10mg
    472,00€
    25mg
    753,00€
    50mg
    1.017,00€
    100mg
    1.378,00€
    500mg
    2.737,00€
    1mL*10mM (DMSO)
    360,00€
  • Patecibart

    CAS:
    <p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>
    Purezza:98%
    Colore e forma:Liquid

    Ref: TM-T81538

    ne
    Fuori produzione
    1mg
    Fuori produzione
    5mg
    Fuori produzione
    50mg
    Fuori produzione
    Prodotto fuori produzione