CaSR
Il recettore sensibile al calcio (CaSR) è un GPCR che svolge un ruolo vitale nel mantenimento dell'omeostasi del calcio regolando la secrezione dell'ormone paratiroideo e il riassorbimento del calcio nei reni. Il CaSR è anche coinvolto in vari altri processi fisiologici, tra cui il metabolismo osseo e la funzione vascolare. I modulatori del CaSR sono utilizzati nel trattamento di condizioni come l'iperparatiroidismo, l'osteoporosi e le malattie cardiovascolari. Presso CymitQuimica, offriamo una selezione di modulatori del CaSR di alta qualità per supportare la tua ricerca nel metabolismo del calcio, endocrinologia e salute delle ossa.
Trovati 34 prodotti di "CaSR"
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Strontium ranelate
CAS:<p>Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.</p>Formula:C12H6N2O8S·2SrPurezza:98.97%Colore e forma:Crystalline SolidPeso molecolare:513.49AC265347
CAS:<p>AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.</p>Formula:C17H17NOSPurezza:>99.99%Colore e forma:SolidPeso molecolare:283.39Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Formula:C24H26N2O2Purezza:98.88% - 99.68%Colore e forma:SolidPeso molecolare:374.48Etelcalcetide
CAS:<p>Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.</p>Formula:C38H73N21O10S2Purezza:98%Colore e forma:SolidPeso molecolare:1048.26Poly-D-lysine hydrobromide (MW 1000-5000)
<p>Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.</p>Colore e forma:Odour SolidPoly-D-lysine hydrobromide (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.Colore e forma:Odour SolidUpacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Formula:C11H15Cl2N3O6SPurezza:98.56%Colore e forma:SoildPeso molecolare:388.22γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Formula:C11H17F3N2O7Colore e forma:SolidPeso molecolare:346.26G-Glu-Val
CAS:<p>G-Glu-Val (γ-glutamyl-L-valine, H-Glu-Val -OH), a flavour-regulating dipeptide, is a major contributor to "mellow".</p>Formula:C10H18N2O5Colore e forma:SolidPeso molecolare:246.26Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Formula:C23H24N2O2Colore e forma:SolidPeso molecolare:360.45Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Formula:C22H22F3NPurezza:99.48%Colore e forma:Yellow OilPeso molecolare:357.41NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Formula:C24H25ClN2O2·HClPurezza:99.38% - 99.67%Colore e forma:SolidPeso molecolare:445.38TNCA
CAS:<p>TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.</p>Formula:C12H12N2O2Purezza:97.33% - 97.73%Colore e forma:SolidPeso molecolare:216.24Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Formula:C33H40O18Purezza:98% - 99.92%Colore e forma:SolidPeso molecolare:724.66Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFormula:Cl3GdPurezza:98%Colore e forma:White Crystalline SolidPeso molecolare:263.61Cinacalcet hydrochloride
CAS:<p>Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-</p>Formula:C22H23ClF3NPurezza:99.96% - >99.99%Colore e forma:Off-White To Tan SolidPeso molecolare:393.87Etelcalcetide hydrochloride
CAS:<p>Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.</p>Formula:C38H73N21O10S2HClPurezza:>99.99%Colore e forma:SolidPeso molecolare:1353.33NPS2390
CAS:<p>NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)</p>Formula:C19H21N3OPurezza:97.13%Colore e forma:SolidPeso molecolare:307.39Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFormula:C18H22ClNOColore e forma:SolidPeso molecolare:303.83SB-423562 HCl
CAS:SB-423562 is a calcium-sensing receptor antagonist.Formula:C26H33ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:473
