Recettore OX
I recettori dell'orexina (OX1 e OX2) sono GPCR che si legano alle orexine, neuropeptidi coinvolti nella regolazione della veglia, dell'appetito e dell'omeostasi energetica. La disregolazione della segnalazione dell'orexina è collegata a disturbi del sonno come la narcolessia e a condizioni metaboliche come l'obesità. I modulatori dei recettori dell'orexina sono studiati per il loro potenziale terapeutico nel trattamento dei disturbi del sonno, dell'ansia e della dipendenza. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori dell'orexina di alta qualità per supportare la tua ricerca in biologia del sonno, metabolismo e neurofarmacologia.
Trovati 42 prodotti di "Recettore OX"
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YNT-185
CAS:YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,Formula:C33H37N5O5SPurezza:99.67%Colore e forma:SolidPeso molecolare:615.74Seltorexant
CAS:Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.Formula:C21H22FN7OPurezza:99.79% - >99.99%Colore e forma:SolidPeso molecolare:407.44Ref: TM-T12877L
1mg37,00€2mg52,00€5mg79,00€10mg103,00€25mg153,00€50mg274,00€100mg378,00€500mg868,00€1mL*10mM (DMSO)87,00€Filorexant
CAS:Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).Formula:C24H25FN4O2Purezza:98.88%Colore e forma:SolidPeso molecolare:420.48EMPA
CAS:EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nMFormula:C23H26N4O4SPurezza:99.11%Colore e forma:SolidPeso molecolare:454.54Ref: TM-T11186
1mg51,00€2mgPrezzo su richiesta5mg97,00€10mg150,00€25mg264,00€50mg396,00€100mg595,00€200mg838,00€1mL*10mM (DMSO)110,00€Suntinorexton
CAS:Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.Formula:C23H28F2N2O4SPurezza:99.89%Colore e forma:SolidPeso molecolare:466.54Ref: TM-T39807
1mg174,00€5mg440,00€10mg704,00€25mg1.074,00€50mg1.448,00€100mg1.892,00€200mg2.539,00€1mL*10mM (DMSO)452,00€SB-408124
CAS:SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formula:C19H18F2N4OPurezza:99.81%Colore e forma:SolidPeso molecolare:356.37[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).Formula:C122H210N44O37SPurezza:98.18%Colore e forma:SolidPeso molecolare:2917.31Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Formula:C130H219N45O40S2Colore e forma:SolidPeso molecolare:3116.54OXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formula:C79H125N23O22Purezza:98%Colore e forma:SolidPeso molecolare:1749Orexin B, rat, mouse
CAS:Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.Formula:C126H215N45O34SPurezza:98%Colore e forma:SolidPeso molecolare:2936.45ZL-1101
ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.Colore e forma:Odour LiquidOrexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Formula:C154H247N47O46S4Colore e forma:SolidPeso molecolare:3621.15[Ala11,D-Leu15]-Orexin B(human)
CAS:OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).Formula:C120H206N44O35SPurezza:98%Colore e forma:SolidPeso molecolare:2857.28Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Formula:C154H244N47F3O46S4Purezza:98%Colore e forma:SolidPeso molecolare:3675.12OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).Formula:C81H126F3N23O24Colore e forma:SolidPeso molecolare:1863Orexin B, human
CAS:Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.Formula:C123H212N44O35SPurezza:98%Colore e forma:SolidPeso molecolare:2899.34Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Formula:C152H243N47O44S4Purezza:98%Colore e forma:SolidPeso molecolare:3561.1Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.Formula:C128H216F3N45O36SColore e forma:SolidPeso molecolare:3050.42SB-674042
CAS:SB-674042 is a nonpeptide dual antagonist of the appetite peptides OX1 and OX2 receptors.SB-674042 is used in the treatment of depression.Formula:C24H21FN4O2SPurezza:99.87% - 99.9%Colore e forma:SolidPeso molecolare:448.51Orexin 2 Receptor Agonist
CAS:Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.Formula:C32H34N4O5SPurezza:98.26% - 99.43%Colore e forma:SolidPeso molecolare:586.7Ref: TM-T3177
2mg42,00€5mg64,00€10mg80,00€25mg137,00€50mg233,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)81,00€
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