Recettore OX
I recettori dell'orexina (OX1 e OX2) sono GPCR che si legano alle orexine, neuropeptidi coinvolti nella regolazione della veglia, dell'appetito e dell'omeostasi energetica. La disregolazione della segnalazione dell'orexina è collegata a disturbi del sonno come la narcolessia e a condizioni metaboliche come l'obesità. I modulatori dei recettori dell'orexina sono studiati per il loro potenziale terapeutico nel trattamento dei disturbi del sonno, dell'ansia e della dipendenza. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori dell'orexina di alta qualità per supportare la tua ricerca in biologia del sonno, metabolismo e neurofarmacologia.
Trovati 40 prodotti di "Recettore OX"
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Filorexant
CAS:<p>Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).</p>Formula:C24H25FN4O2Purezza:98.88%Colore e forma:SolidPeso molecolare:420.48Seltorexant
CAS:<p>Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.</p>Formula:C21H22FN7OPurezza:99.79% - >99.99%Colore e forma:SolidPeso molecolare:407.44EMPA
CAS:<p>EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM</p>Formula:C23H26N4O4SPurezza:99.11%Colore e forma:SolidPeso molecolare:454.54YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Formula:C33H37N5O5SPurezza:99.67%Colore e forma:SolidPeso molecolare:615.74SB-408124
CAS:<p>SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.</p>Formula:C19H18F2N4OPurezza:99.81%Colore e forma:SolidPeso molecolare:356.37Suntinorexton
CAS:<p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>Formula:C23H28F2N2O4SPurezza:99.89%Colore e forma:SolidPeso molecolare:466.54OXA(17-33)
CAS:<p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>Formula:C79H125N23O22Purezza:98%Colore e forma:SolidPeso molecolare:1749Orexin A (human, rat, mouse) acetate
<p>Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.</p>Formula:C154H247N47O46S4Colore e forma:SolidPeso molecolare:3621.15[Ala11,D-Leu15]-Orexin B acetate
<p>[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).</p>Formula:C122H210N44O37SPurezza:98.18%Colore e forma:SolidPeso molecolare:2917.31Orexin B, rat, mouse
CAS:<p>Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.</p>Formula:C126H215N45O34SPurezza:98%Colore e forma:SolidPeso molecolare:2936.45[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Formula:C120H206N44O35SPurezza:98%Colore e forma:SolidPeso molecolare:2857.28Orexin B, rat, mouse TFA
<p>Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>Formula:C128H216F3N45O36SColore e forma:SolidPeso molecolare:3050.42ZL-1101
<p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>Colore e forma:Odour LiquidXenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Formula:C130H219N45O40S2Colore e forma:SolidPeso molecolare:3116.54Orexin A (human, rat, mouse)
CAS:<p>Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.</p>Formula:C152H243N47O44S4Purezza:98%Colore e forma:SolidPeso molecolare:3561.1OXA(17-33) TFA
<p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>Formula:C81H126F3N23O24Colore e forma:SolidPeso molecolare:1863Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Formula:C154H244N47F3O46S4Purezza:98%Colore e forma:SolidPeso molecolare:3675.12Orexin B, human
CAS:<p>Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.</p>Formula:C123H212N44O35SPurezza:98%Colore e forma:SolidPeso molecolare:2899.34SB-674042
CAS:<p>SB-674042 is a nonpeptide dual antagonist of the appetite peptides OX1 and OX2 receptors.SB-674042 is used in the treatment of depression.</p>Formula:C24H21FN4O2SPurezza:99.9%Colore e forma:SolidPeso molecolare:448.51OXA (17-33) acetate
<p>OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).</p>Formula:C79H125N23O22Purezza:98.52%Colore e forma:SolidPeso molecolare:1748.98
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