Recettore dell'adenosina
I recettori dell'adenosina sono una classe di GPCR che rispondono al nucleoside endogeno adenosina. Questi recettori sono coinvolti nella regolazione di vari processi fisiologici, tra cui la funzione cardiovascolare, i cicli sonno-veglia e le risposte immunitarie. I modulatori dei recettori dell'adenosina hanno un potenziale terapeutico nel trattamento di condizioni come le aritmie cardiache, l'infiammazione e le malattie neurodegenerative. Presso CymitQuimica, offriamo una selezione di modulatori dei recettori dell'adenosina di alta qualità per supportare la tua ricerca in biologia cardiovascolare, neuroscienze e immunologia.
Trovati 214 prodotti per "Recettore dell'adenosina".
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ATL802
CAS:ATL802 is an adenosine A2B Receptor antagonist.Formula:C24H22F3N7O3Purezza:98%Colore e forma:SolidPeso molecolare:513.47Sulmazole
CAS:Sulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.Formula:C14H13N3O2SPurezza:99.94%Colore e forma:White SolidPeso molecolare:287.34PSB-1901
CAS:PSB-1901: potent A2B Adenosine Receptor Antagonist; Ki=0.0835 nM; >10,000x selective; effective in mice for preclinical studies.Formula:C24H25BrN6O4SPurezza:99.65%Colore e forma:White SolidPeso molecolare:573.46PSB-1115 potassium salt
CAS:PSB-1115 potassium salt, a selective A2B Adenosine Receptor antagonist, inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) [1].Formula:C14H13KN4O5SColore e forma:SolidPeso molecolare:388.44MRS5698
CAS:MRS5698, an A3 adenosine receptor agonist with Ki ~3 nM, blocks chronic pain, highly selective (>1000-fold over A1/A2A).Formula:C28H23ClF2N6O3Purezza:98%Colore e forma:SolidPeso molecolare:564.97Xanthine amine congener
CAS:Xanthine amine congener is an Adenosine receptor antagonist.Formula:C21H28N6O4Purezza:99.7%Colore e forma:SolidPeso molecolare:428.48ABT-702 hydrochloride
CAS:ABT-702 hydrochloride effectively inhibits adenosine kinase, exhibiting an IC50 value of 1.7 nM [1] [2].Formula:C22H20BrClN6OColore e forma:SolidPeso molecolare:499.79PSB-603
CAS:PSB-603 is a selective antagonist of Adenosine A2B receptor(Ki = 0.553 nM) with anti-inflammatory effects.Formula:C24H25ClN6O4SPurezza:97.14%Colore e forma:SolidPeso molecolare:529.01Ref: TM-T23203
1mg34,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg326,00€50mg532,00€100mg888,00€200mg1.198,00€A2B receptor antagonist 1
CAS:A2B receptor antagonist 1 (EXAMPLE 9B) is a potent A2B adenosine receptor antagonist.Formula:C21H24N6O2Purezza:99.53%Colore e forma:SolidPeso molecolare:392.45Ref: TM-T10058
1mg349,00€5mg697,00€1mL*10mM (DMSO)800,00€10mg888,00€25mg1.395,00€50mg1.783,00€100mg2.530,00€PSB 1115
CAS:PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.Formula:C14H14N4O5SPurezza:98.69% - >99.99%Colore e forma:SolidPeso molecolare:350.35MRS7799
CAS:MRS7799 is a selective A3 Adenosine Receptor antagonist with Kd values of 0.55 nM for humans, 3.74 nM for mice, and 2.80 nM for rats. MRS7799 can be utilized in research related to neurodegenerative diseases, cancer, cardiac and cerebral ischemia, and autoimmune inflammatory diseases.Formula:C22H18N4OSColore e forma:SolidPeso molecolare:386.47ATL444
CAS:ATL444 is an adenosine receptor antagonist with affinity (Ki values) for rA1AR, rA2AAR, rA2BAR, and rA3AR of 7.0, 2.5, 61.8, and >1000 nM, respectively.Formula:C17H19N5OColore e forma:SolidPeso molecolare:309.37Adenosine receptor antagonist 6
CAS:Adenosine receptor antagonist 6 is an orally active, selective (S)-enantiomer compound that acts as an A2A adenosine receptor (A2AAR) antagonist. It binds to the A2A adenosine receptor with a Ki value of 19.18 nM. This antagonist inhibits cAMP production mediated by 5’-N-ethylcarboxamide adenosine (NECA) with an IC50 value of 0.089 μM and reduces immunosuppression, while enhancing the secretion of IL-2 and IFN-γ. It counteracts adenosine-induced immunosuppression in T cell activation and cytokine release and inhibits tumor growth in CT26/MC38 xenograft models, making it applicable for colorectal cancer research.Formula:C18H16N6OPeso molecolare:332.36A2AR modulator-1
CAS:A2AR modulator-1 (Compound 45) is a selective negative allosteric modulator of the adenosine A2a receptor (A2aR), with an IC50 value of 9 nM. It reduces the affinity of endogenous adenosine for the receptor and inhibits the activation of the cAMP signaling pathway. A2AR modulator-1 effectively restores pCREB phosphorylation in CD4+ T cells, reverses immunosuppression in the tumor microenvironment, and shows potential in inhibiting tumor growth and metastasis in a triple-negative breast cancer model.Formula:C23H20N6Colore e forma:SolidPeso molecolare:380.45L-97-1
CAS:L-97-1 is an antagonist of the adenosine A1 receptor.Formula:C29H38N6O3Purezza:98%Colore e forma:SolidPeso molecolare:518.65M1069
M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.Formula:C25H30N4O8SColore e forma:SolidPeso molecolare:546.59Neladenoson
CAS:Neladenoson is an effective and selective agonist of the Adenosine A1 Receptor (A1R). EGFR-IN-162 shows potential for research in heart failure.Formula:C29H24ClN5O2S2Colore e forma:SolidPeso molecolare:574.12MSX-3
CAS:MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.Formula:C21H23N4Na2O7PPurezza:98%Colore e forma:SolidPeso molecolare:520.389DMPX
CAS:DMPX (3,7-Dimethyl-1-propargylxanthine) is a caffeine-like compound capable of crossing the blood-brain barrier. It serves as an A2-selective adenosine receptor (AR) antagonist, effectively and selectively blocking the hypothermia and behavioral inhibition induced by A2 adenosine receptor agonists, such as NECA. DMPX is utilized in research on diseases like Parkinson's disease.Formula:C10H10N4O2Colore e forma:SolidPeso molecolare:218.212A2A receptor antagonist 2
A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).Formula:C25H28FN7O3Colore e forma:SolidPeso molecolare:493.53
