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Recettore GNRH

Recettore GNRH

I recettori dell'ormone di rilascio delle gonadotropine (GnRH) sono GPCR che si legano al GnRH, un ormone responsabile della regolazione del rilascio dell'ormone luteinizzante (LH) e dell'ormone follicolo-stimolante (FSH) dalla ghiandola pituitaria. Questi recettori sono cruciali per la funzione riproduttiva e sono bersagliati nelle terapie per condizioni come il cancro alla prostata, l'endometriosi e l'infertilità. Gli agonisti e gli antagonisti dei recettori del GnRH sono anche utilizzati nelle tecnologie di riproduzione assistita. Presso CymitQuimica, offriamo una gamma completa di modulatori dei recettori del GnRH di alta qualità per supportare la tua ricerca in salute riproduttiva, endocrinologia e terapia ormonale.

Trovati 91 prodotti per "Recettore GNRH".

prodotti per pagina.
  • DCOIT
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    DCOIT

    CAS:
    DCOIT, an isothiazolinone derivative, stimulates the synthesis of follicle-stimulating hormone and luteinizing hormone in the brain by activating the gonadotropin-releasing hormone receptor (GnRHR). Additionally, it interferes with G protein-coupled receptors, MAPK, and Ca 2+ signaling pathways [1].
    Formula:C11H17Cl2NOS
    Colore e forma:Solid
    Peso molecolare:282.23

    Ref: TM-T84706

  • BAY-899
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    BAY-899

    CAS:
    BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.
    Formula:C25H19F2N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:459.4475

    Ref: TM-T10476

  • GnRH antagonist 2
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    GnRH antagonist 2

    CAS:
    GnRH antagonist 2 is a GnRH receptor antagonist, useful for studying endocrine diseases.
    Formula:C28H27F2N9O5
    Purezza:98.08%
    Colore e forma:Solid
    Peso molecolare:607.5681

    Ref: TM-T37003

  • Abarelix acetate
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    Abarelix acetate

    CAS:
    Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.
    Formula:C72H95ClN14O14·xC2H4O2
    Colore e forma:Solid
    Peso molecolare:1476.14

    Ref: TM-T68701

  • Logo CymitQuimica
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    GnRH-R antagonist-2

    CAS:
    GnRH-R antagonist-2 (Compound 44c) is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist, with IC50 values of 43 nM for rat and 88 nM for human GnRH-R. It is applicable in studies related to hormone-dependent diseases such as endometriosis, breast cancer, and prostate cancer[1].
    Formula:C37H50N4O3S
    Peso molecolare:630.89

    Ref: TM-T213283

  • Merigolix
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    Merigolix

    CAS:
    Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist .
    Formula:C36H35F7N4O6
    Colore e forma:Solid
    Peso molecolare:752.68

    Ref: TM-T73327

  • Acyline
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    Acyline

    CAS:
    Acyline, a GnRH antagonist, suppresses gonadotropins and testosterone in animals and maintains the effect for 2 weeks in men with one dose.
    Formula:C80H102ClN15O14
    Colore e forma:Solid
    Peso molecolare:1533.21

    Ref: TM-T70266

  • Logo CymitQuimica
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    Elagolix

    CAS:
    Elagolix is an orally active, highly effective, selective non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRH receptor) with a dissociation constant (KD) of 54 pM, as well as an NFAT inhibitor, and is utilized in researching endometriosis-related pain.
    Formula:C32H30F5N3O5
    Peso molecolare:631.6

    Ref: TM-T214231

  • GnRH-R antagonist 1
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    GnRH-R antagonist 1

    CAS:
    Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.
    Formula:C31H28F5N7O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:721.65

    Ref: TM-T72492

  • Metallibure
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    Metallibure

    CAS:
    Metallibure (ICI 33828) is a derivative of dithiocarbamoyl hydrazine and functions as a gonadotrophic inhibitor. It interferes with the action of pituitary gonadotropins in bony fish, thereby inhibiting the maturation of germ cells. While Metallibure does not affect the histological structure of the thyroid, it does reduce the nuclear volume of thyroid epithelial cells. This compound is utilized in the study of endocrine disorders.
    Formula:C7H14N4S2
    Peso molecolare:218.343

    Ref: TM-T214308

  • Logo CymitQuimica
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    (R)-BAY-899

    (R)-BAY-899: R-isomer, selective LH-R antagonist, effective on hLH (IC50: 185 nM) and rLH (IC50: 46 nM), orally active.
    Formula:C25H19F2N5O2
    Colore e forma:Solid
    Peso molecolare:459.45

    Ref: TM-T62881