Sintesi del DNA/RNA
Gli inibitori della sintesi di DNA e RNA sono composti che interferiscono con i processi di replicazione e trascrizione nelle cellule, impedendo così la produzione di materiale genetico essenziale. Questi inibitori possono bersagliare vari enzimi e proteine coinvolti nella sintesi degli acidi nucleici, rendendoli strumenti preziosi per lo studio dei meccanismi di replicazione, trascrizione e traduzione. Sono inoltre utilizzati nello sviluppo di trattamenti per infezioni e cancro. Presso CymitQuimica, offriamo un ampio spettro di inibitori della sintesi di DNA/RNA per supportare la vostra ricerca in biologia molecolare, virologia e sviluppo terapeutico.
Trovati 799 prodotti di "Sintesi del DNA/RNA"
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12R-LOX-IN-1
CAS:12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX.Formula:C15H11NO2Colore e forma:SolidPeso molecolare:237.25pppApG
CAS:pppApG serves as an initial substrate for the synthesis of vRNA (viral RNA) and cRNA (complementary RNA), with applications in influenza virus research [1].Formula:C20H28N10O20P4Colore e forma:SolidPeso molecolare:852.39Thymidine-5'-O-(α,β-methylene)diphosphate sodium
CAS:Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM).Formula:C11H15N2O10P2·3NaColore e forma:SolidPeso molecolare:466.16FAICAR
CAS:FAICAR (5-Formamidoimidazole-4-carboxamide ribotide), a purine nucleotide, plays a crucial role in metabolic processes.Formula:C10H15N4O9PColore e forma:SolidPeso molecolare:366.22PD 121373
CAS:PD 121373, a Benzothiopyrano-indazole, inhibits nucleic acid synthesis, equally affecting DNA/RNA.Formula:C21H27N5OSColore e forma:SolidPeso molecolare:397.54NSC15520
CAS:NSC15520 is an RPA inhibitor that inhibits helical destabilization of double-stranded DNA oligonucleotides and can be used to study DNA damage repair.Formula:C24H34O6Colore e forma:SolidPeso molecolare:418.52TAS-114
CAS:TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.Formula:C21H29N3O6SPurezza:99.76%Colore e forma:SolidPeso molecolare:451.54DNA polymerase-IN-3
CAS:DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications inFormula:C13H12O4Purezza:98%Colore e forma:SolidPeso molecolare:232.23Cytidine 3'-monophosphate
CAS:Cytidine 3'-monophosphate, a ribonucleotide, results from the hydrolysis of cytidine 2',3'-cyclic monophosphate via RNase—a process that cytidine 3'-monophosphate itself inhibits. Additionally, it can be dephosphorylated to cytidine by 3'-nucleotidase.Formula:C9H14N3O8PColore e forma:SolidPeso molecolare:323.2CCT239065
CAS:CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600EBRAF and LCK inhibitor.Formula:C29H29N7O3SColore e forma:SolidPeso molecolare:555.655-DACTHF
CAS:5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.Formula:C19H24N6O6Purezza:98%Colore e forma:SolidPeso molecolare:432.43DAM-IN-1
CAS:DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.Formula:C16H17NO4Purezza:98%Colore e forma:SolidPeso molecolare:287.31UNC2170 maleate
CAS:53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.Formula:C14H21BrN2OC4H4O4Colore e forma:SolidPeso molecolare:429.31Diazoketone methotrexate
CAS:Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.Formula:C21H22N10O4Colore e forma:SolidPeso molecolare:478.46DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurezza:97.8% - 99.76%Colore e forma:SolidPeso molecolare:495.43Ref: TM-T27135
1mg90,00€5mg253,00€10mg379,00€25mg640,00€50mg892,00€100mg1.224,00€1mL*10mM (DMSO)275,00€G4/HDAC-IN-1
G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.Formula:C36H49ClFN7O4Colore e forma:SolidPeso molecolare:698.27Balapiravir hydrochloride
CAS:Balapiravir HCl, an NS5B inhibitor, is used potentially for the treatment of HCV infection.Formula:C21H31ClN6O8Colore e forma:SolidPeso molecolare:530.96Filibuvir
CAS:Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.Formula:C29H37N5O3Purezza:99.28% - >99.99%Colore e forma:SolidPeso molecolare:503.64Gossypolone
CAS:Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.Formula:C30H26O10Purezza:99.15%Colore e forma:SolidPeso molecolare:546.52Ref: TM-T31987
1mg185,00€5mg426,00€10mg627,00€25mg938,00€50mg1.320,00€100mg1.786,00€500mg3.591,00€1mL*10mM (DMSO)535,00€LNA-Adenosine
CAS:LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.Formula:C11H13N5O4Purezza:99.15%Colore e forma:SolidPeso molecolare:279.25
