Sintesi del DNA/RNA
Gli inibitori della sintesi di DNA e RNA sono composti che interferiscono con i processi di replicazione e trascrizione nelle cellule, impedendo così la produzione di materiale genetico essenziale. Questi inibitori possono bersagliare vari enzimi e proteine coinvolti nella sintesi degli acidi nucleici, rendendoli strumenti preziosi per lo studio dei meccanismi di replicazione, trascrizione e traduzione. Sono inoltre utilizzati nello sviluppo di trattamenti per infezioni e cancro. Presso CymitQuimica, offriamo un ampio spettro di inibitori della sintesi di DNA/RNA per supportare la vostra ricerca in biologia molecolare, virologia e sviluppo terapeutico.
Trovati 799 prodotti di "Sintesi del DNA/RNA"
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Thymectacin
CAS:Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.Formula:C21H25BrN3O9PPurezza:97.05% - 99.49%Colore e forma:SolidPeso molecolare:574.32SMN-C3
CAS:SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).Formula:C24H28N6OPurezza:99.01% - 99.05%Colore e forma:SolidPeso molecolare:416.52DHX9-IN-2
CAS:DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.Formula:C18H16ClN3O3S2Purezza:98%Colore e forma:SolidPeso molecolare:421.92Ref: TM-T82568
1mg97,00€5mg243,00€10mg376,00€25mg538,00€50mg700,00€100mg905,00€1mL*10mM (DMSO)265,00€CeMMEC1
CAS:CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).Formula:C19H16N2O4Purezza:98.9% - 99.92%Colore e forma:SolidPeso molecolare:336.34Sorivudine
CAS:Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.Formula:C11H13BrN2O6Purezza:99.74%Colore e forma:SolidPeso molecolare:349.13Lomibuvir
CAS:Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.Formula:C25H35NO4SPurezza:99.83%Colore e forma:SolidPeso molecolare:445.612'-(2-Nitrobenzyl)-ATP
CAS:2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.Formula:C17H21N6O15P3Colore e forma:SolidPeso molecolare:642.30Adafosbuvir
CAS:Adafosbuvir has antiviral activity.Formula:C22H29FN3O10PColore e forma:SolidPeso molecolare:545.457L-2'-Fd4C
CAS:L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].Formula:C9H10FN3O3Colore e forma:SolidPeso molecolare:227.19DHX9-IN-19
CAS:DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.Formula:C20H21ClN4O4S2Colore e forma:SolidPeso molecolare:480.988Antitumor agent-74
Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.Formula:C26H23FN6Colore e forma:SolidPeso molecolare:438.5Polθ-IN-8
CAS:Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.Formula:C22H22ClN7O3SColore e forma:SolidPeso molecolare:499.973'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite
CAS:3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.Formula:C41H50N9O3PColore e forma:SolidPeso molecolare:747.87DNA polymerase-IN-6
CAS:DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.Formula:C26H28ClFN8O4Colore e forma:SolidPeso molecolare:571.003Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Formula:C9H20N2O8Colore e forma:SolidPeso molecolare:284.26Dencatistat
CAS:Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.Formula:C24H27N7O5SPurezza:98.85%Colore e forma:SolidPeso molecolare:525.58Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFormula:C23H22N4O2Colore e forma:SolidPeso molecolare:386.45WRN inhibitor 13
CAS:WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.Formula:C16H20N2O5SColore e forma:SolidPeso molecolare:352.405CB 30900
CAS:CB30900 is a novel and effective thymidylate synthase inhibitor.Formula:C31H32FN5O9Colore e forma:SolidPeso molecolare:637.61DENV-IN-6
CAS:DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.Formula:C23H26ClFN4OSColore e forma:SolidPeso molecolare:461
