Proteasi HIV
Gli inibitori della proteasi dell'HIV sono una classe di farmaci antiretrovirali che bersagliano specificamente l'enzima proteasi del virus dell'immunodeficienza umana (HIV). Inibendo questo enzima, questi composti impediscono al virus di elaborare le sue poliproteine in proteine mature e funzionali, bloccando così la produzione di nuovi virioni infettivi. Gli inibitori della proteasi dell'HIV sono una pietra miliare della terapia antiretrovirale altamente attiva (HAART) utilizzata per gestire l'HIV/AIDS. Presso CymitQuimica, offriamo una varietà di inibitori della proteasi dell'HIV per supportare la vostra ricerca nel trattamento dell'HIV, nella resistenza ai farmaci e nella virologia.
Trovati 505 prodotti di "Proteasi HIV"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
HIV-1 integrase inhibitor 3
CAS:HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).Formula:C21H22F2N4O4Purezza:98%Colore e forma:SolidPeso molecolare:432.427-Deaza-2',3'-dideoxyguanosine
CAS:7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate that inhibits HIV-1 reverse transcriptase with a Ki of 25 nM [1].Formula:C11H14N4O3Colore e forma:SolidPeso molecolare:250.25GSK3532795
CAS:GSK3532795: potent oral HIV-1 maturation inhibitor; EC50: 1.9-13 nM for various strains.Formula:C42H62N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:691.02Teropavimab
CAS:Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].Colore e forma:LiquidL-696229
CAS:L-696229: specific HIV-1 RT inhibitor, blocks viral spread in various cells.Formula:C17H18N2O2Purezza:98%Colore e forma:SolidPeso molecolare:282.34Ulonivirine
CAS:Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.Formula:C18H8ClF6N5O3Colore e forma:SolidPeso molecolare:491.73DGKα-IN-8
CAS:DGKα-IN-8 (Example 51) is a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibiting an IC50 of 22.491 nM and an EC50 of 0.256 nM.Formula:C23H19ClF3N5OColore e forma:SolidPeso molecolare:473.88Murabutide
CAS:Murabutide, a safe synthetic immunomodulator, diminishes the expression of CD4 and CCR5 receptors and promotes the secretion of high levels of beta-chemokines,Formula:C23H40N4O11Colore e forma:SolidPeso molecolare:548.58Fosalvudine tidoxil
CAS:Fosalvudine tidoxil, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C35H64FN2O8PSPurezza:98%Colore e forma:SolidPeso molecolare:722.93GSK3839919A
CAS:GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].Formula:C36H46ClN3O3Colore e forma:SolidPeso molecolare:604.22Hinokinin
CAS:Hinokinin (Cubebinolide), a bioactive lignan, exhibits a broad spectrum of pharmacological activities.Formula:C20H18O6Colore e forma:SolidPeso molecolare:354.35PNU-103017
CAS:PNU-103017 is an inhibitor of HIV protease.Formula:C28H28N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:504.6BMS-955176 HCl
CAS:GSK-3532795: a broader-spectrum HIV-1 maturation inhibitor than bevirimat, effective in vitro and clinically.Formula:C42H62N2O4SColore e forma:SolidPeso molecolare:727.486Azt-pmap
CAS:AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].Formula:C20H25N6O8PPurezza:98%Colore e forma:SolidPeso molecolare:508.42Berlopentin
CAS:Berlopentin is splenopentin analog used to treat HIV-positive patients. It also has immunostimulatory properties.Formula:C35H55N9O11Colore e forma:SolidPeso molecolare:777.86Capravirine
CAS:Capravirine, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C20H20Cl2N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:451.37HIV-1 inhibitor-3
CAS:HIV-1 inhibitor-3 is an HIV infection inhibitor.Formula:C9H10F2N2O5Purezza:98%Colore e forma:SolidPeso molecolare:264.18L-697661
CAS:L-697661, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C16H15Cl2N3O2Colore e forma:SolidPeso molecolare:352.22Indinavir, threo-
CAS:Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS.Formula:C36H47N5O4Purezza:98%Colore e forma:SolidPeso molecolare:613.79A 74704
CAS:A 74704 is a pseudo C2-symmetric inhibitor of HIV-1 protease and its diester analog.Formula:C43H52N4O7Purezza:98%Colore e forma:SolidPeso molecolare:736.9Droxinavir HCl
CAS:Droxinavir HCl is an antiviral agent and HIV protease inhibitor.Formula:C29H52ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:570.22NNRTIs-IN-1
CAS:NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-typeFormula:C28H22N6O3Colore e forma:SolidPeso molecolare:490.51Palinavir
CAS:Palinavir is an antiviral, it inhibits HIV-1 protease.Formula:C41H52N6O5Purezza:98%Colore e forma:SolidPeso molecolare:708.89L 687908
CAS:L 687908 is a potent inhibitor of hydroxyethylene-containing HIV protease.Formula:C40H51N5O5Purezza:98%Colore e forma:SolidPeso molecolare:681.863′-Deoxy Thymidine
CAS:3′-Deoxy Thymidine is a nucleoside analog of thymidine with antiviral activity. 3′-Deoxy Thymidine inhibit HIV replication in peripheral blood mononuclear cells (EC50 = 0.17 µM). 3′-Deoxy Thymidine also decreases plaque formation in CV-1 cells infected with HSV-1 at micromolar concentrations. These properties support the use of 3′-Deoxy Thymidine in antiviral mechanism studies and nucleoside analog evaluation.Formula:C10H14N2O4Purezza:99.89%Colore e forma:SolidPeso molecolare:226.23I-XW-053
CAS:I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-Formula:C22H16N2O2Purezza:99.05%Colore e forma:SolidPeso molecolare:340.37R 87366
CAS:R 87366 is used as a water-soluble HIV protease inhibitor.Formula:C32H39N7O6Purezza:98%Colore e forma:SolidPeso molecolare:617.7Rp-dGTPαS
CAS:Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].Formula:C10H16N5O12P3SColore e forma:SolidPeso molecolare:523.25Cgp 57813
CAS:CGP 57813 is a lipophilic compound, which can be used as an inhibitor of HIV-1 protease.Formula:C43H58N4O8Colore e forma:SolidPeso molecolare:758.94SW106
CAS:SW106 blocks PTHR1 cAMP signaling, not affecting mutant PTHR1-T410P/H223R.Formula:C16H14F5NO2Colore e forma:SolidPeso molecolare:347.28Hydroxy Darunavir
CAS:Hydroxy darunavir, a metabolite of the HIV-1 protease inhibitor darunavir, is generated through isobutyl aliphatic hydroxylation of darunavir.Formula:C27H37N3O8SColore e forma:SolidPeso molecolare:563.66L 694746
CAS:L 694746 is an inhibitor of HIV-1 protease.Formula:C35H42N2O8Purezza:98%Colore e forma:SolidPeso molecolare:618.72KNI-272
CAS:Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.Formula:C33H41N5O6S2Colore e forma:SolidPeso molecolare:667.8412-Bromododecanoic Acid
CAS:12-Bromododecanoic acid, a halogenated derivative of lauric acid, serves in the synthesis of clickable myristic acid derivatives and functions as a model fatty acid ligand for elucidating the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes. This compound, at a concentration of 10 µg/ml, has been shown to diminish virion DNA in the culture supernatant of primary hepatocytes from a duckling model of hepatitis B virus (HBV) infection and exhibits inhibitory activity against HIV replication in CEM-SS T cells with an EC50 value of 38 µM.Formula:C12H23BrO2Colore e forma:SolidPeso molecolare:279.218DMP 323
CAS:DMP 323 is a potent inhibitor of HIV-1 protease.Formula:C35H38N2O5Purezza:98%Colore e forma:SolidPeso molecolare:566.69L-689502
CAS:L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).Formula:C39H51N3O7Purezza:98%Colore e forma:SolidPeso molecolare:673.84Reverse transcriptase-IN-1
CAS:Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Formula:C25H17N7O2Purezza:99.61%Colore e forma:SolidPeso molecolare:447.45Ref: TM-T12715
1mg64,00€5mg131,00€10mg183,00€25mg311,00€50mg449,00€100mg615,00€200mg833,00€1mL*10mM (DMSO)143,00€HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormula:C26H37N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:503.65HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Formula:C25H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:489.63HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formula:C68H104N10O12SPurezza:98%Colore e forma:SolidPeso molecolare:1285.68HIV-1 protease-IN-12
CAS:HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-Formula:C25H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:489.63HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFormula:C37H41N7O4SPurezza:98%Colore e forma:SolidPeso molecolare:679.83PYR01
CAS:PYR01 is a potent nonnucleoside reverse transcriptase inhibitor of HIV-1 and concurrently acts as a targeted activator to eliminate cells expressing HIV-1 [1].Formula:C21H13F7N4O3Colore e forma:SolidPeso molecolare:502.34Bavtavirine
CAS:Bavtavirine is a non-nucleoside reverse HIV-1 transcriptase inhibitor (NNRTIs),inhibits HIV replication by preventing the transcription of viral RNA into DNA.
Formula:C26H20N6Purezza:97.2%Colore e forma:SolidPeso molecolare:416.48U 89360E
CAS:U 89360E is a peptidic inhibitor.Formula:C28H52N8O6Purezza:98%Colore e forma:SolidPeso molecolare:596.76U 104489
CAS:U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF.Formula:C26H36N6O3SColore e forma:SolidPeso molecolare:512.67HIV-1 inhibitor-10
CAS:HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.Formula:C39H54O6Colore e forma:SolidPeso molecolare:618.84BILR-355
CAS:BILR-355 is a reverse transcriptase inhibitor.Formula:C25H23N5O3Purezza:98%Colore e forma:SolidPeso molecolare:441.48XZ426
CAS:XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity .Formula:C22H24F2N4O4Colore e forma:SolidPeso molecolare:446.45BMS-561390
CAS:BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C14H12ClF3N2OColore e forma:SolidPeso molecolare:316.71A 77003
CAS:A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.Formula:C44H58N8O6Colore e forma:SolidPeso molecolare:794.98WRNA10
CAS:WRNA10 is a potent binding agent for HIV-1TAR RNA (IC50: 10 μM, CC50: 40 μM).Formula:C25H32N4O4Colore e forma:SolidPeso molecolare:452.55PDDC inhibitor
CAS:PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.Formula:C27H29N5O4Purezza:96.09% - 99.39%Colore e forma:SolidPeso molecolare:487.55HIV-1 inhibitor-54
CAS:HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Formula:C27H30N6O4SPurezza:98.05% - 99.39%Colore e forma:SoildPeso molecolare:534.63HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).Formula:C27H31N3O6SColore e forma:SolidPeso molecolare:525.62Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Colore e forma:SolidPeso molecolare:157.21HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Formula:C16H15F2N3OSColore e forma:SolidPeso molecolare:335.37(S)-Batylalcohol
CAS:(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.Formula:C21H44O3Colore e forma:SolidPeso molecolare:344.572Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:229.264'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purezza:98%Colore e forma:SolidPeso molecolare:275.26Methyl piperazine-2-carboxylate
CAS:Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.Formula:C6H12N2O2Colore e forma:SolidPeso molecolare:144.172HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Formula:C27H31FN2O6SColore e forma:SolidPeso molecolare:530.61Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColore e forma:SolidPeso molecolare:487.19Saphenamycin
CAS:Saphenamycin is an antibiotic from a strain of Streptomyces.Formula:C23H18N2O5Purezza:98%Colore e forma:SolidPeso molecolare:402.40GS-9822
CAS:GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formula:C36H39ClN4O4SColore e forma:SolidPeso molecolare:659.24BMIM-TFSI
CAS:BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.Formula:C10H15F6N3O4S2Colore e forma:SolidPeso molecolare:419.364Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColore e forma:SolidPeso molecolare:349.858HIV-1 inhibitor-13
HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).Formula:C30H32N6O3Colore e forma:SolidPeso molecolare:524.61PD 134922
CAS:PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Formula:C37H61N5O7SPurezza:98%Colore e forma:SolidPeso molecolare:719.97Telinavir
CAS:Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.Formula:C33H44N6O5Colore e forma:SolidPeso molecolare:604.74BI 224436
CAS:BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.Formula:C27H26N2O4Colore e forma:SolidPeso molecolare:442.51GSK3739936
CAS:GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.
Formula:C34H43FN2O4Colore e forma:SolidPeso molecolare:562.71MIV-150
CAS:MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formula:C19H17FN4O3Purezza:98%Colore e forma:SolidPeso molecolare:368.36ZK-316
CAS:ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Formula:C27H22D6N6O3S2Colore e forma:SolidPeso molecolare:554.72A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purezza:98%Colore e forma:SolidPeso molecolare:794.98HIV-1 inhibitor-40
HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.Formula:C25H18N6O2Colore e forma:SolidPeso molecolare:434.45BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColore e forma:SolidPeso molecolare:570.619Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColore e forma:SolidPeso molecolare:727.07HIV-1 inhibitor-52
CAS:HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.Formula:C46H72FNO5SColore e forma:SolidPeso molecolare:770.13HIV-1 inhibitor-61
CAS:HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].Formula:C24H24F2N2O2SColore e forma:SolidPeso molecolare:442.52BI-2540
CAS:BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Formula:C24H15ClF5NO5Colore e forma:SolidPeso molecolare:527.83L 702007
CAS:L 702007 is an inhibitor of HIV-1 reverse transcriptase.Formula:C18H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:315.41HIV-1 inhibitor-14
HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.Formula:C29H32N6O4SColore e forma:SolidPeso molecolare:560.67HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formula:C25H21N5OSColore e forma:SolidPeso molecolare:439.53NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Formula:C20H25ClN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:436.96ZLM-66
ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.
Colore e forma:SolidHIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).Formula:C23H26N2O4SColore e forma:SolidPeso molecolare:426.53HIV-1 inhibitor-17
HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).Formula:C32H32N4O5SColore e forma:SolidPeso molecolare:584.69HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.Formula:C21H32ClN7O3Colore e forma:SolidPeso molecolare:465.98NBD-14189
CAS:NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Formula:C18H16F4N4O2SColore e forma:SolidPeso molecolare:428.40HIV-1 inhibitor-82
CAS:HIV-1inhibitor-82 (Compound L14) is a small molecule inhibitor of HIV-1 entry with oral bioavailability, exhibiting an IC50 value of 0.39 μM. It holds potential for research in combating HIV-1 infection.Formula:C37H37ClN2O6S2Colore e forma:SolidPeso molecolare:705.28BRN3OMe
CAS:BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.
Formula:C7H13N3O4Colore e forma:SolidPeso molecolare:203.196DPC 684
CAS:DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.Formula:C35H48FN5O5SColore e forma:SolidPeso molecolare:669.85NNRT-IN-2
CAS:NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].Formula:C19H14F3N5O3Peso molecolare:417.34Desthiazolylmethyl ritonavir
CAS:Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.Formula:C33H43N5O4SColore e forma:SolidPeso molecolare:605.791HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formula:C20H17N3O7SColore e forma:SolidPeso molecolare:443.43Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).Formula:C33H41NO6SColore e forma:SolidPeso molecolare:579.75ATPase-IN-6
CAS:ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.Formula:C29H25N3O4SColore e forma:SolidPeso molecolare:511.59L-697639
CAS:L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.Formula:C18H21N3O2Colore e forma:SolidPeso molecolare:311.38BRD-K98645985
CAS:BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Formula:C33H43N5O4Purezza:98%Colore e forma:SolidPeso molecolare:573.73BMS-378806
BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.
Formula:C22H22N4O4Purezza:98%Colore e forma:SolidPeso molecolare:406.433-Deazaadenosine
CAS:3-Deazaadenosine, an inhibitor of S-adenosylhomocysteine hydrolase with a Ki of 3.9 μM, exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.Formula:C11H14N4O4Purezza:98%Colore e forma:SolidPeso molecolare:266.25Aurothioglucose
CAS:Aurothioglucose is a active-site TrxR1 inhibitor.Formula:C6H11AuO5SPurezza:98%Colore e forma:Yellow Crystals SolidPeso molecolare:392.18Oxindole
CAS:Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.
Formula:C8H7NOPurezza:99.34%Colore e forma:Off-White Crystalline PowderPeso molecolare:133.15HIV-1 integrase inhibitor
CAS:Hiv-1 integrase inhibitor is an effective anti-HIV drug.Formula:C11H9N3O4Purezza:98%Colore e forma:SolidPeso molecolare:247.21
