Antibatterico

Tigecycline hydrochloride is a first-in-class, broad-spectrum antibiotic. It also has activity against antibiotic-resistant organisms.

Antibacterialagent 285 (Compound 3) is a cephalosporin antibiotic. It exhibits significant antibacterial activity against Gram-negative bacteria, with minimum inhibitory concentrations (MIC) of 0.125-0.5 μg/mL for carbapenem-resistant Acinetobacter baumannii (CRAB), 0.125-0.5 μg/mL for Klebsiella pneumoniae (CRE), and 0.125-2 μg/mL for Pseudomonas aeruginosa (CRPA). Antibacterialagent 285 can be utilized in bacterial infection research, including studies on complicated urinary tract infections (cUTI) and kidney infections.

Ibezapolstat hydrochloride is an antibacterial agent.

Antibacterial agent 49 (example 12) is a antibacterial agent.

2,2'-Dihydroxy chalcone inhibits β-glucuronidase (IC50=1.6 μM) and lysozyme (IC50=1.4 μM), and fights E. coli, S. fowleri, S. albicans, S. aureus.

Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.

Bostrycin, an anthraquinone derived from B. alpestre, exhibits a broad spectrum of biological activities including antibacterial, antiproliferative, and phytotoxic effects. This compound demonstrates efficacy against Gram-positive bacteria like methicillin-resistant S. aureus (MRSA), M. tuberculosis, and C. botulinum. Additionally, Bostrycin shows antiproliferative action against A549 lung adenocarcinoma cells, particularly by arresting the cell cycle at the G0/G1 phase and triggering apoptosis within a concentration range of 10 to 30 µM. As a phytotoxin, it causes necrosis in water hyacinth leaves at approximately 7 µg/ml. Furthermore, Bostrycin serves as a protein immobilization cross-linking agent, managing to preserve its bacteriostatic properties when affixed to nonwoven polypropylene fabric.

Drimentine A: Antibiotic from Actinomycete, fights Gram-positive/negative bacteria, fungi, yeast, and has anthelmintic traits.

EP5-1 is an antimicrobial peptide with antibacterial, antifungal, antitumor, and antiviral properties, notably inducing apoptosis in cancer cells and

Brevinin-1E, an antimicrobial peptide, originates from the skin secretions of the Rana esculenta (European green frog) [1].

TXY541 is an orally active antibacterial agent that is converted into PC190723 under physiological conditions. It demonstrates strong antibacterial activity against Staphylococcus aureus and exhibits low cytotoxicity towards mammalian cells.

Antitubercular agent-52 (Compound 7k) is a chemical compound that acts as an antitubercular agent targeting Mycobacterium tuberculosis (Mtb). It specifically inhibits the bacterium's cytochrome bcc (cyt-bcc) electron transport chain and also affects cytochrome bd (cyt-bd). By disrupting a crucial energy metabolism pathway in Mtb, Antitubercular agent-52 impedes electron transport and ATP production, showing potential for use in tuberculosis research.

CHEMBL1380345 fights S. aureus, B. cereus, E. coli; pMICs: 3.64, 3.56, 3.70.

Armentomycin is a kind of chlorinated nonprotein amino acid.

WAY-604663 (2,3-diphenylquinoxaline-6-sulfonamide) may have antibacterial analgesic and anti-inflammatory activities.

Dactylocyclines: new tetracycline derivatives from Dactylosporangium fermentation, including isolated glycosides.

4-Trehalosamine, a microbial metabolite identified in Streptomyces, exhibits antibiotic properties.

Y 12896 has a wide range of applications in life science related research.

SCH 725674, a macrolide, halts fungi like S. cerevisiae and C. albicans growth; MICs are 8 and 32 μg/ml.

Antituberculosis agent-15 (Compound 18c) is a selective antimycobacterial agent with a minimum inhibitory concentration (MIC) of 0.45 μM against Mycobacterium tuberculosis H37Rv (ATCC 27294) and 0.28 μM against its wild-type strain H37Rv-LP (ATCC 25618). It exhibits potent intracellular inhibitory activity in macrophage infection models, with an IC50 of 0.16 μM. Antituberculosis agent-15 is applicable for tuberculosis research.

Cacaoidin, a glycosylated lantibiotic extracted from Streptomyces cacaoi, exhibits strong antibacterial effects against Gram-positive pathogens, notably

13-Deoxycarminomycin is an antitumor antibiotic.

α/β-Hydrolase-IN-1 demonstrates exceptional potency, with MICs of 50 μM (25 μg/mL) against M.

Cis-2-dodecenoic acid, identified in Burkholderia cenocepacia, disrupts bacterial quorum sensing, thereby inhibiting biofilm formation and the production of

Quaternium-15 cis-form: cosmetic preservative/antistatic, not dermal teratogen, tested in rats.

Cuprichydroxide exhibits inhibitory activity against Ralstonia solanacearum and A549 cells and has acute pulmonary toxicity.

5'-Methoxynobiletin is a useful organic compound for research related to life sciences and the catalog number is T124370.

ChlaDUB1-IN-1 (Compound 8) is an inhibitor of the Chlamydia deubiquitinase enzyme 1 (ChlaDUB1) and serves as a potential agent in antimicrobial research.

Feglymycin, a 13-amino acid peptide, counters Gram-positive bacteria and HIV, blocks E. coli enzymes MurA & MurC.

Targeting thebacterialsliding clamp peptide 46 TFA is a short peptide that specifically targets the bacterial sliding clamp (SC) and inhibits SC-dependent DNA synthesis.

Arylomycin A5 is a lipohexapeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

ATP synthase inhibitor3 (compound PT6) is an orally active inhibitor targeting the F-ATP synthase of Mycobacterium tuberculosis (IC50=0.788 μM). It effectively inhibits the growth of the Mycobacterium tuberculosis H37Rv strain (ATCC-27294) in vitro, depleting intracellular ATP levels at an IC50 of 30 μM.

Isoleucylcysteine is the first intermediate peptide in bacitracin biosynthesis.

Chitotriose, a low molecular weight chitosan oligosaccharide, is extractable from crab shell chitosan. It exhibits antibacterial properties against salmonella.

Arizonin A1 is a biochemical.

Anilazine is a pesticide that is used on crops. It comes under the category of triazine fungicides.

Carbendazim mixture with flusilazole is a bioactive chemical.

Guaiacylglycerol-beta-guaiacyl Ether is degraded by microorganisms and is commonly used as a substrate to mimic microbial degradation of cell walls of lignin-living plants.

Antibacterialagent 270 (Compound 3e) is an antibacterial agent that targets bacterial membrane components such as phosphatidylglycerol (PG), cardiolipin (CL), and bacterial DNA. It disrupts the bacterial membrane structure and binds to DNA, interfering with genetic information transfer. Antibacterialagent 270 holds potential for research into infections caused by methicillin-resistant Staphylococcus aureus (MRSA).

Pleurocidin, an antibacterial peptide, originates from the skin secretions of the Winter Flounder (Pseudopleuronectes americanus) [1].

Nanangenine F, a drimane sesquiterpene from A. nanangensis, inhibits B. subtilis (IC50=78μg/ml) and is cytotoxic to various cells (IC50=49-95μg/ml).

3-O-Methylellagic acid from Myrciaria cauliflora is anti-inflammatory, inhibits glucose transport, and kills Staph. Aureus at 32 μg/mL.

BTK-IN-39 (0204) is a PROTAC target protein ligand employed in the synthesis of PROTAC BTK Degrader-11.

Isoegomaketone (IK), an essential oil component in P. frutescens, displays anti-inflammatory and antitumor properties. It has been demonstrated to alleviate inflammatory response and oxidative stress in sepsis-induced ALI, positioning it as a potential therapeutic agent for managing sepsis-associated ALI.

Cinerubine A is an anthracycline.

4-(2-Octylamino)diphenylamine is an aromatic amine antioxidant known to be toxic to V. fischeri, with an IC50 value of 0.68 mg/mL. It induces skin sensitization and contact dermatitis in the murine local lymph node assay and can be used as a rubber additive.

LeuRS-IN-1 is a leucyl-tRNA synthetase inhibitor with anti-leukemic and anti-malarial activity that inhibits M.tb LeuRS.

Compound YJ196 (Compound 59) serves as an inhibitor of New Delhi Metallo-β-lactamase-1 (NDM-1) [1].

Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells.

Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor.

Triglysin B, an antimicrobial peptide, inhibits the growth of other streptococci [1].

Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.

Primulasaponin 1 is a useful organic compound for research related to life sciences. The catalog number is T124469 and the CAS number is 65312-86-9.

Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic properties.

Tacrolimus-13C-d2 is the 13C and deuterated compound of Tacrolimus.

Polymyxin B1: potent lipopeptide against multidrug-resistant Gram-negative bacteria; from Bacillus polymyxa.

4-Aminosalicylic acid (Standard) is the standard substance of 4-Aminosalicylic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Valacyclovir hydrochloride (Standard) is the standard substance of Valacyclovir hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that, upon metabolism, inhibits viral DNA replication.

Phenoxyethanol (Standard) is the standard substance of Phenoxyethanol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.

Methylisothiazolinone (Standard) is the standard substance of Methylisothiazolinone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.

1-Tetradecanol (Standard) is the standard substance of 1-Tetradecanol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 1-Tetradecanol is a natural product with antibacterial and anti-inflammatory proterties.

Ornidazole (Standard) is the standard substance of Ornidazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.

D-Cystine, the D-enantiomer of L-Cystine, functions as an inhibitor of L-aspartate-β-semialdehyde dehydrogenase (ASADH) derived from Escherichia coli.

Sodium diacetate, a colorless solid, is a flavor enhancer and antimicrobial used widely in food additives.

Desmeninol, found in urine and cytoplasm, is used in organic synthesis, dye-making, medicine, photo-coloring, and as a fungicide.

BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.

Exo2 is a secretion inhibitor that disrupts trans-Golgi network (TGN) and interferes with the delivery of Shiga toxin to the endoplasmic lumen,.

Lactoferrin (17-41) (Standard) is a reference material for analytical use. Lactoferrin (17-41) exhibits broad-spectrum antimicrobial activity.

N,N',N''-Triacetylchitotriose is a competitive inhibitor of lysozyme.

Sulopenem (CP-70429) is a gastrointestinally absorbed carbapenem antibiotic with broad-spectrum antibacterial activity, inhibiting both Gram-positive.

Kanamycin sulfate (Standard) is the standard substance of Kanamycin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.

Furazolidone (Standard) is the standard substance of Furazolidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,

Bronopol (Standard) is the standard substance of Bronopol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Bronopol (BNPD) is an antimicrobial agent with low mammalian toxicity (at in-use levels) and high activity against bacteria, especially the troublesome Gram-negative species.

Lactate potassium inhibits bacterial growth and serves as a pH regulator and preservative.

Nosiheptide (Standard) is the standard substance of Nosiheptide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nosiheptide (Multhiomycin), a thiopeptide antibiotic synthesized by Streptomyces actuosus, serves as a potent feed additive to promote animal growth. It functions by hindering bacterial protein synthesis and is distinguished by an indole side ring system and regiospecific hydroxyl groups on its macrocyclic core.

(S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanoic acid is a biochemical reagent that can be used in biological research.

Cefoxitin, an oral 2nd-gen cephalosporin antibiotic, combats Gram+/- & anaerobes, for abdominal and gynecological infections.

Kasugamycin hydrochloride (Standard) is the standard substance of Kasugamycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Monensin sodium salt (Standard) is the standard substance of Monensin sodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion

Sulfisoxazole (Standard) is the standard substance of Sulfisoxazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A.

Cimetidine (Standard) is the standard substance of Cimetidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.

Zinc pyrithione (Standard) is an analytical standard and reference sample. Zinc pyrithione (OM-1563) disrupts membrane transport by inhibiting proton pumps.

Cephradine (Standard) is the standard substance of Cephradine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

TBI-223 is an orally effective antibiotic against M. tuberculosis and against methicillin-resistant S. aureus infections in mouse interference model.

Chlorhexidine diacetate (Standard) is the standard substance of Chlorhexidine diacetate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Sulfapyridine (Standard) is the standard substance of Sulfapyridine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.

Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.

Sulfapyridine D4 a deuterium labeled Sulfapyridine. Sulfapyridine is a agent of sulfonamide antibacterial.

Cyclosporin C (Cs-C) is a fungal metabolite against filamentous phytopathogenic fungi.

Ternidazole hydrochloride (Ternidazole HCl) is a 5-nitroimidazole antibiotic with antimicrobial antioxidant and antiprotozoal activity.

Balofloxacin is a fluoroquinolone antibiotic with oral activity.

Deuterium-labeled Sulfamethazine, an antimicrobial for treating animal diseases.

5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.

Fosmidomycin sodium salt (FR-31564 sodium salt) is an anti-infective antibiotic with anti-malarial activity that inhibits both Gram-negative bacteria.

3-Nitrophenylboronic acid has antibacterial activity and can be used in research and experiments in the field of life sciences.

G907 is an antagonist of the ATP-binding cassette (ABC) transporter protein MsbA with bactericidal activity. G907 inhibits MsbA in E. coli.

Metronidazole-d4 is a deuterium labeled compound isotopic tracing.Metronidazole is an antibiotic and antiprotozoal oral and BBB penetration anaerobic bacteria.

2-Cyclopentenone can inhibit the activity of HepG2 cells and has inhibitory activity against urease in Sporosarcina pasteurii.