Antibatterico

Avarol triggers cell death in pancreatic cancer and is a non-toxic, neuroprotective AChE inhibitor for Alzheimer's.

NSC309401 is an E. coli dihydrofolate reductase inhibitor with an IC50 value of 189 nM and a dissociation constant (Kd) of 14.57 nM [1].

Chloramine-T serves as a versatile reagent in numerous synthetic procedures, including aminohydroxylation, allylic amination, as a nitrogen source in aziridination reactions of alkenes and olefins, and for the deprotection of thio groups in sulfur-containing molecules. Additionally, it plays a role in the synthesis of Factor Xa inhibitors. At a concentration of 0.2% w/v, Chloramine-T acts as an effective antiseptic agent with bactericidal properties against S. epidermidis, S. aureus, E. faecalis, E. coli, P. mirabilis, and E. cloacae.

Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections.

Sphinganine (d16:0 branched), an aniso-branched sphingolipid, is identified as a constituent of ceramide-containing phospholipids in bacteria.

Urease-IN-6, a potent Urease inhibitor, exhibits an IC50 value of 14.2 μM and is utilized in the research of peptic and gastric ulcers [1].

Nilofabicin (CG-400549) is a potent inhibitor of enoyl-(acyl-carrier-protein) reductase fall(FabI) and can be used in studies about the treatment of complicated

AU1235 is a Mycobacterium tuberculosis inhibitor.

I-A09 is a noncompetitive mPTPB inhibitor.

Bassianolide, a cyclodepsipeptide insecticide produced by the fungal species B. bassiana and V. lecanii, demonstrates significant biological activity. Upon oral administration, it induces atony in B. mori silkworms at a concentration of 4 ppm and becomes lethal when concentrations exceed 8 ppm. Remarkably, atony in silkworm larvae can also be triggered by doses as low as 2 µg/larva. Further studies reveal that bassianolide (0.01-1 µM) specifically targets muscarinic receptors to inhibit contractions in isolated guinea pig smooth muscle tissue, elicited by acetylcholine, without affecting nicotinic receptor-induced contractions.

Tylvalosin (Acetylisovaleryltylosin) is a broad-spectrum macrolide antibiotic with antibacterial and antiviral properties, effective against PRRSV infection.

Dihydropleuromutilin, a semisynthetic antibiotic derived from pleuromutilin, exhibits antimicrobial efficacy against S. aureus, M. hominis, M. gallisepticum, and M. hyorhinis, with minimum inhibitory concentrations (MICs) of 0.5, 0.3, 0.3, and 2 µg/ml, respectively.

Mansonone F is a topoisomerase II inhibitor with cytotoxic and topo inhibitory potencies.

DuP-721: broad-spectrum, oral antibiotic targeting various bacteria, including M. tuberculosis.

LtaS-IN-1 inhibits LTA synthesis in MDR E. faecium; alters cell walls; MIC: 0.5-64 μg/mL for 28 Enterococcus strains.

<p>S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a</p>

NIK-250 is a P-glycoprotein inhibitor. NIK250 could reverse multidrug resistance in human glioma cells.

Antibacterial agent 93: potent aaRS inhibitor; effective against certain gram-positive and negative bacteria.

4-Aminobenzylphosphonic acid, an inhibitor of alkaline phosphatase (Ki= 1.1 mM for the bovine intestine enzyme), is utilized in affinity chromatography for alkaline phosphatase purification and in the electrochemical modification of glassy carbon electrodes.

Antibacterial compound 1 is an antibacterial compound.