gsk-3
Gli inibitori di GSK-3 sono composti che prendono di mira la Glicogeno Sintasi Chinasi 3 (GSK-3), un enzima coinvolto in numerosi processi cellulari, tra cui il metabolismo del glicogeno, la trascrizione genica e la proliferazione cellulare. GSK-3 è implicata in varie malattie, come il diabete, i disturbi neurodegenerativi e il cancro. Gli inibitori di GSK-3 sono strumenti importanti per esplorare queste vie e sviluppare potenziali terapie. Presso CymitQuimica, forniamo inibitori di GSK-3 per supportare la tua ricerca nelle malattie metaboliche, nella neurobiologia e nell'oncologia.
Trovati 111 prodotti di "gsk-3"
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9-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Formula:C22H13FN2O5Purezza:99.32%Colore e forma:SolidPeso molecolare:404.35Indazole
CAS:<p>Indazole, a heterocyclic compound, offers diverse biological activities.</p>Formula:C7H6N2Purezza:99.59% - 99.85%Colore e forma:White Or Beige Crystalline PowderPeso molecolare:118.14BRD0705
CAS:BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.Formula:C20H23N3OPurezza:99.01%Colore e forma:SolidPeso molecolare:321.42Cyanoacetohydrazide
CAS:Cyanoacetohydrazide (Cyanoacetic hydrazide) is an anti-TB drug. It has also been used to derive compounds that may have antitumor properties.Formula:C3H5N3OPurezza:99.78%Colore e forma:Stout Prisms From Alcohol Slightly Brown PowderPeso molecolare:99.09Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purezza:99.4% - 99.95%Colore e forma:Colorless Crystals From Ethanol + Ether White Crystalline PowderPeso molecolare:512.33GSK-3β inhibitor 24
GSK-3β inhibitor24 (Compound 41) is a potent GSK-3β inhibitor with an IC50 of 0.22 nM. It increases GSK-3β phosphorylation at the Ser9 site in a dose-dependent manner and inhibits tau protein hyperphosphorylation by reducing the abundance of p-tau-Ser396. The compound upregulates β-catenin and neurogenesis-related markers (GAP43 and MAP-2), demonstrating significant anti-Alzheimer's disease (AD) activity.Formula:C26H18N4O3Colore e forma:SolidPeso molecolare:434.446GSK3β Inhibitor XI
CAS:GSK3β Inhibitor XI has GSK3β inhibitory effect.Formula:C18H15N5O3Colore e forma:SolidPeso molecolare:349.35GSK-3β inhibitor 1
CAS:GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurezza:99.40%Colore e forma:SolidPeso molecolare:222.24Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Colore e forma:Odour Solid2B-(SP)
CAS:Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)Formula:C71H123N26O29PPurezza:98%Colore e forma:SolidPeso molecolare:1835.87BMP agonist 1
BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.Formula:C21H16N2O6Colore e forma:SolidPeso molecolare:392.36GSK3β/mTOR modulator 1
<p>GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.</p>Formula:C19H28O5Colore e forma:SolidPeso molecolare:336.19367GSK-3β inhibitor 19
<p>GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of 70 nM. It is applicable in research related to anti-inflammatory and Alzheimer's disease.</p>Formula:C15H12N4O2SColore e forma:SolidPeso molecolare:312.35GSK-3β inhibitor 23
GSK-3β inhibitor23 (Compound 11726169) is an inhibitor of glycogen synthase kinase 3 (GSK-3), effectively inhibiting GSK-3β and GSK-3α with IC50 values of 12.1 nM and 18.8 nM, respectively. It demonstrates antiviral activity against HIV1 and exhibits good metabolic stability in mouse and human liver microsomes and plasma, although it has poor permeability in Caco-2 cells, indicating potentially low oral bioavailability.Formula:C18H13Cl2N5O2SColore e forma:SolidPeso molecolare:434.299MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formula:C17H12BrN3O2Purezza:99.64%Colore e forma:SolidPeso molecolare:370.2GSK-3β inhibitor 21
GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.Colore e forma:Odour SolidGSK-3 Inhibitor 5
CAS:<p>4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.</p>Formula:C9H6BrNOPurezza:99.58%Colore e forma:Off-White To Light Yellow Crystalline PowderPeso molecolare:224.05FRATide
CAS:<p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>Formula:C55H102N2O2Colore e forma:SolidPeso molecolare:823.4336-Me-ATP
CAS:<p>6-Me-ATP, a modified ATP, binds well to GSK3 and donates phosphate for GSK3β phosphorylation.</p>Formula:C11H18N5O13P3Colore e forma:SolidPeso molecolare:521.21CHIR-98023
CAS:CHIR-98023 is a bio-active chemical.Formula:C20H16Cl2N8O2Colore e forma:SolidPeso molecolare:471.30
