gsk-3

CHIR-99021 (CT99021) is a GSK-3α/β inhibitor (IC50: 10/6.7 nM).

BIO-acetoxime is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over …

TCS 21311 is an effective and highly selective inhibitor of JAK3 (IC50: 8 nM). TCS …

Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM …

GSK3i XIII is a GSK-3 ATP-binding site inhibitor.

Charantin is a steroidal saponin isolated from Momordica charantia. It increases the release of insulin …

Indirubin-3'-oxime is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( …

5-bromoindole is a potential inhibitor of glycogen synthase kinase 3 (GSK-3)and an important pharmaceutical chemical …

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β( IC50s of …

BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: …

GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive …

Ginsenoside Rg2 is one of the major active components of ginseng, act as an NF-κB …

GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high …

Kenpaullone, a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. …

9-ING-41 is a glycogen synthase kinase-3 inhibitor.

Gypenoside XVII confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation …

4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).

AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating …

Tideglusib, a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and …

CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free …

A 1070722 is a potent and selective GSK-3 inhibitor, shows high affinity GSK-3α(Ki = 0.6 …

GSK-3 inhibitor 1 is a GSK-3 inhibitor.

AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and …

LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based …

TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation

AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.

Bikinin, a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR …

Cyanoacetohydrazide is an anti-TB drug.

1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity …

TBB(NSC 231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).

CP21R7 is an effective and specific GSK3β inhibitor. It is used as an activator of …

BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705. BRD0705 is a GSK3α inhibitor (IC50: 66 …

Lecanoric acid shows antioxidant activity with an IC50 value of 79-95 ug/ml, it at 100 …

BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor. With IC50s of 16 nM and …

BIO is a specific inhibitor of GSK-3.

SB216763 is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).

PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity …

PHA-767491 is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 …

AT7519 hydrochloride is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.

GSK-3β inhibitor 2 is a selective and orally active GSK-3β inhibitor (IC50: 1.1 nM). GSK-3β …

SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective …

SNS-032 is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and …

IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.

TDZD-8 is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect …

AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor.