gsk-3
Gli inibitori di GSK-3 sono composti che prendono di mira la Glicogeno Sintasi Chinasi 3 (GSK-3), un enzima coinvolto in numerosi processi cellulari, tra cui il metabolismo del glicogeno, la trascrizione genica e la proliferazione cellulare. GSK-3 è implicata in varie malattie, come il diabete, i disturbi neurodegenerativi e il cancro. Gli inibitori di GSK-3 sono strumenti importanti per esplorare queste vie e sviluppare potenziali terapie. Presso CymitQuimica, forniamo inibitori di GSK-3 per supportare la tua ricerca nelle malattie metaboliche, nella neurobiologia e nell'oncologia.
Trovati 110 prodotti di "gsk-3"
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TDZD-8
CAS:TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.Formula:C10H10N2O2SPurezza:97.13% - 99.61%Colore e forma:White SolidPeso molecolare:222.26Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purezza:97.51% - 98.75%Colore e forma:Orange SolidPeso molecolare:412.48Ref: TM-T6513
5mg66,00€10mg99,00€25mg188,00€50mg350,00€100mg469,00€1mL*10mM (DMSO)Prezzo su richiestaSB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formula:C19H12Cl2N2O2Purezza:98.9% - 99.13%Colore e forma:SolidPeso molecolare:371.22Ref: TM-T3077
2mg39,00€5mg52,00€10mg79,00€25mg131,00€50mg197,00€100mg334,00€500mg803,00€1mL*10mM (DMSO)52,00€CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formula:C19H15N3O2Purezza:96.14% - 99.16%Colore e forma:SolidPeso molecolare:317.34Ref: TM-T3684
1mg40,00€2mg52,00€5mg88,00€10mg127,00€25mg250,00€50mg376,00€100mg567,00€1mL*10mM (DMSO)81,00€GSK 3 Inhibitor IX
CAS:<p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>Formula:C16H10BrN3O2Purezza:98% - 99.72%Colore e forma:SolidPeso molecolare:356.17Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purezza:99.55%Colore e forma:Dark Red SolidPeso molecolare:277.28Ref: TM-T5200
2mg35,00€5mg52,00€10mg85,00€25mg156,00€50mg235,00€100mg349,00€200mg538,00€1mL*10mM (DMSO)58,00€PF-04802367
CAS:PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.Formula:C16H16ClN5O3Purezza:98.76%Colore e forma:SolidPeso molecolare:361.78Ref: TM-T9611
1mg52,00€5mg105,00€10mg160,00€25mg279,00€50mg420,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)117,00€KY19382
CAS:KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.Formula:C17H11Cl2N3O2Purezza:98.06%Colore e forma:SolidPeso molecolare:360.19Ref: TM-T9025
1mg99,00€5mg197,00€10mg350,00€25mg590,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)243,00€IM-12
CAS:<p>IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.</p>Formula:C22H20FN3O2Purezza:99.42% - >99.99%Colore e forma:SolidPeso molecolare:377.41Tideglusib
CAS:Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.Formula:C19H14N2O2SPurezza:98.40% - 99.35%Colore e forma:SolidPeso molecolare:334.39Ref: TM-T3067
10mg47,00€25mg77,00€50mg113,00€100mg187,00€200mg283,00€500mg490,00€1mL*10mM (DMSO)50,00€LY2090314
CAS:LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia and advanced cancers.Formula:C28H25FN6O3Purezza:99.21% - 99.91%Colore e forma:SolidPeso molecolare:512.53Ref: TM-T1755
1mg37,00€2mg52,00€5mg95,00€10mg138,00€25mg238,00€50mg389,00€100mg575,00€200mg820,00€1mL*10mM (DMSO)97,00€GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Formula:C16H11N5O2SPurezza:98.86%Colore e forma:SolidPeso molecolare:337.36Ref: TM-T8605
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)178,00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purezza:97.72% - 99.75%Colore e forma:SolidPeso molecolare:334.37Ref: TM-T1741
1mg43,00€2mg56,00€5mg85,00€10mg124,00€25mg219,00€50mg350,00€100mg429,00€1mL*10mM (DMSO)63,00€BIO-acetoxime
CAS:<p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>Formula:C18H12BrN3O3Purezza:97.15%Colore e forma:SolidPeso molecolare:398.21Bikinin
CAS:<p>Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.</p>Formula:C9H9BrN2O3Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:273.08SB 415286
CAS:SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.Formula:C16H10ClN3O5Purezza:99.55%Colore e forma:SolidPeso molecolare:359.72GSK-3β inhibitor 10
CAS:GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.Formula:C12H12N2O3SPurezza:98.06%Colore e forma:SolidPeso molecolare:264.3RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purezza:98% - 99.91%Colore e forma:SolidPeso molecolare:545.63GNF4877
CAS:GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.Formula:C25H27FN6O4Purezza:98.68% - 99.40%Colore e forma:SolidPeso molecolare:494.52(E/Z)-GSK-3β inhibitor 1
CAS:(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.Formula:C14H10N2OPurezza:98.60%Colore e forma:SolidPeso molecolare:222.24Ref: TM-T9178
2mg38,00€5mg59,00€10mg88,00€25mg162,00€50mg235,00€100mg335,00€200mg457,00€1mL*10mM (DMSO)66,00€
