AMPK
Gli inibitori di AMPK sono composti che inibiscono la Proteina Chinasi Attivata da AMP (AMPK), un enzima che svolge un ruolo critico nell'omeostasi energetica cellulare. AMPK si attiva in risposta a bassi livelli di energia nelle cellule e aiuta a regolare processi come l'assorbimento del glucosio, l'ossidazione degli acidi grassi e la biogenesi mitocondriale. Inibire AMPK è importante per studiare il suo ruolo nelle malattie metaboliche, nel cancro e nell'invecchiamento. Presso CymitQuimica, offriamo una gamma di inibitori di AMPK per supportare la tua ricerca in metabolismo, oncologia e malattie legate all'età.
Trovati 171 prodotti di "AMPK"
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COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formula:C13H8Cl4N2OPurezza:98.96%Colore e forma:SolidPeso molecolare:350.03Marein
CAS:Marein prevents PC12 cell damage by protecting mitochondria and activating AMPK, potentially countering diabetic encephalopathy.Formula:C21H22O11Purezza:99.12% - 99.84%Colore e forma:SolidPeso molecolare:450.39Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formula:C24H25N5OPurezza:98% - 99.06%Colore e forma:SolidPeso molecolare:399.49Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formula:C19H36O5Purezza:99.85% - 99.94%Colore e forma:SolidPeso molecolare:344.49Ref: TM-T3625
2mg35,00€5mg52,00€10mg73,00€25mg125,00€50mg217,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)55,00€Mogroside I E1
CAS:Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Formula:C36H62O9Purezza:98.62% - 99.71%Colore e forma:SolidPeso molecolare:638.87Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formula:C22H30N6OSBrHPurezza:97.83% - 99.92%Colore e forma:SolidPeso molecolare:628.86Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purezza:97.58% - 98%Colore e forma:SolidPeso molecolare:330.35STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Formula:C25H23N3O4SPurezza:98.66%Colore e forma:SolidPeso molecolare:461.53SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Formula:C21H21BrN4O5Purezza:99.13%Colore e forma:SolidPeso molecolare:489.32Gomisin J
CAS:Gomisin J is a natural product and have vasodilatory activity.Formula:C22H28O6Purezza:99.59% - 99.60%Colore e forma:SolidPeso molecolare:388.45Ref: TM-T3904
1mg47,00€2mg65,00€5mg119,00€10mg188,00€25mg329,00€50mg490,00€100mg700,00€1mL*10mM (DMSO)97,00€GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formula:C21H27N7O3Purezza:98.07% - 99.77%Colore e forma:SolidPeso molecolare:425.48RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormula:C17H20N4O2Purezza:99.30%Colore e forma:SolidPeso molecolare:312.37MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formula:C103H156N28O24S2Purezza:100%Colore e forma:SolidPeso molecolare:2234.64WZ4003
CAS:<p>WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.</p>Formula:C25H29ClN6O3Purezza:99.65% - >99.99%Colore e forma:SolidPeso molecolare:496.99PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurezza:98.82%Colore e forma:SolidPeso molecolare:374.44Ref: TM-T8764
1mg113,00€2mg160,00€5mg230,00€10mg369,00€25mg615,00€50mg879,00€100mg1.198,00€500mg2.395,00€1mL*10mM (DMSO)240,00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formula:C26H37ClN6O2Purezza:98.19%Colore e forma:SolidPeso molecolare:501.07ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formula:C24H27N7OPurezza:99.53% - 99.7%Colore e forma:SolidPeso molecolare:429.52Metformin glycinate
CAS:Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Formula:C6H16N6O2Colore e forma:SolidPeso molecolare:204.23[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Formula:C17H26O4Purezza:98% - 99.66%Colore e forma:Light Yellow OilinessPeso molecolare:294.39
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