AMPK
Gli inibitori di AMPK sono composti che inibiscono la Proteina Chinasi Attivata da AMP (AMPK), un enzima che svolge un ruolo critico nell'omeostasi energetica cellulare. AMPK si attiva in risposta a bassi livelli di energia nelle cellule e aiuta a regolare processi come l'assorbimento del glucosio, l'ossidazione degli acidi grassi e la biogenesi mitocondriale. Inibire AMPK è importante per studiare il suo ruolo nelle malattie metaboliche, nel cancro e nell'invecchiamento. Presso CymitQuimica, offriamo una gamma di inibitori di AMPK per supportare la tua ricerca in metabolismo, oncologia e malattie legate all'età.
Trovati 161 prodotti per "AMPK".
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Resolvin D3
CAS:Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.Formula:C22H32O5Colore e forma:SolidPeso molecolare:376.493AMARA peptide
CAS:AMARA peptide: a minimal substrate for SIK, AMPK, and other protein kinases; contains AMPK phosphorylation site.Formula:C62H115N27O17SPurezza:98%Colore e forma:SolidPeso molecolare:1542.81SAMS
CAS:SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).Formula:C74H131N29O18S2Purezza:98%Colore e forma:SolidPeso molecolare:1779.15NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C24H30N6OColore e forma:SolidPeso molecolare:418.535ALKBH1-IN-3
ALKBH1-IN-3 is an effective inhibitor of the DNA N6-methyladenosine (6mA) demethylase ALKBH1. This compound enhances the abundance of 6mA in gastric cancer cell lines HGC27 and AGS, simultaneously inhibiting cell viability and upregulating the AMP-activated protein kinase (AMPK) signaling pathway. ALKBH1-IN-3 holds potential for use in cancer research, including studies on gastric cancer.Colore e forma:Odour SolidKanglexin
CAS:Kanglexin is an orally active novel anthraquinone compound. It inhibits NLRP3 inflammasome activation and pyroptosis, offering cardioprotective benefits. By stimulating the FGFR1/ERK signaling pathway, Kanglexin promotes angiogenesis and accelerates wound healing in diabetes. Additionally, it has lipid-lowering effects and inhibits vascular smooth muscle cell dedifferentiation, making it a potential compound for studying hyperlipidemia, fatty liver, and atherosclerosis.Formula:C21H18O8Colore e forma:SolidPeso molecolare:398.36Glycometabolism Compound Library
xnum glycometabolism-related comounds, can be used for HTS and HCT;Colore e forma:Odour SolidRef: TM-L2520
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaXY221
XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.Formula:C32H34FN3O5Colore e forma:SolidPeso molecolare:559.628N,N-Didesethyl Sunitinib
CAS:N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.Formula:C18H19FN4O2Purezza:97.73%Colore e forma:Orange SolidPeso molecolare:342.37Ref: TM-T60128
1mg130,00€5mg313,00€1mL*10mM (DMSO)319,00€10mg439,00€25mg713,00€50mg973,00€100mg1.333,00€Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.Colore e forma:Transparent LiquidMetformin-D6 hydrochloride
CAS:Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Formula:C4H12ClN5Purezza:98.1%Colore e forma:SolidPeso molecolare:171.66Teneligliptin hydrobromide hydrate
CAS:Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Formula:C22H33BrN6O2SColore e forma:SolidPeso molecolare:525.516-Azuridine
CAS:6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.Formula:C8H11N3O6Purezza:99.02%Colore e forma:SolidPeso molecolare:245.19BC1618
CAS:BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formula:C24H24F3NO2Purezza:99.95%Colore e forma:SolidPeso molecolare:415.45O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurezza:99.84% - ≥98%Colore e forma:White SolidPeso molecolare:380.25Ref: TM-T7362
1mg63,00€2mg92,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormula:C20H26O3Purezza:99.26% - 99.86%Colore e forma:Off-White To Yellow SolidPeso molecolare:314.42AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formula:C13H18F3N5Purezza:99.86%Colore e forma:SolidPeso molecolare:301.31Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formula:C4H11N5Purezza:99.77% - >99.99%Colore e forma:SolidPeso molecolare:129.16Ref: TM-T8526
10mg44,00€1mL*10mM (DMSO)44,00€25mg66,00€50mg93,00€100mg102,00€500mg250,00€2500mg414,00€Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purezza:97.58% - 98%Colore e forma:SolidPeso molecolare:330.35EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purezza:99.48%Colore e forma:SolidPeso molecolare:644.4Ref: TM-T7955
1mg87,00€2mg114,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)263,00€25mg447,00€50mg620,00€100mg875,00€200mg1.161,00€
