AMPK
Gli inibitori di AMPK sono composti che inibiscono la Proteina Chinasi Attivata da AMP (AMPK), un enzima che svolge un ruolo critico nell'omeostasi energetica cellulare. AMPK si attiva in risposta a bassi livelli di energia nelle cellule e aiuta a regolare processi come l'assorbimento del glucosio, l'ossidazione degli acidi grassi e la biogenesi mitocondriale. Inibire AMPK è importante per studiare il suo ruolo nelle malattie metaboliche, nel cancro e nell'invecchiamento. Presso CymitQuimica, offriamo una gamma di inibitori di AMPK per supportare la tua ricerca in metabolismo, oncologia e malattie legate all'età.
Trovati 168 prodotti di "AMPK"
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O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurezza:99.84% - ≥98%Colore e forma:SolidPeso molecolare:380.25Dorsomorphin dihydrochloride
CAS:Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFormula:C24H25N5O·2HClPurezza:97.74% - 99.89%Colore e forma:SolidPeso molecolare:472.41AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formula:C13H18F3N5Purezza:99.86%Colore e forma:SolidPeso molecolare:301.31GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Formula:C26H20ClN3O5Purezza:97.02% - 97.05%Colore e forma:SolidPeso molecolare:489.91Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formula:C22H30N6OSBrHPurezza:97.83% - 99.92%Colore e forma:SolidPeso molecolare:628.86EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purezza:99.48%Colore e forma:SolidPeso molecolare:644.4Platycodin D
CAS:<p>Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA.</p>Formula:C57H92O28Purezza:99.2% - 99.65%Colore e forma:SolidPeso molecolare:1225.32PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formula:C21H22N6OPurezza:98.82%Colore e forma:SolidPeso molecolare:374.44Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purezza:97.58% - 98%Colore e forma:SolidPeso molecolare:330.35IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purezza:98.07% - 98.14%Colore e forma:SolidPeso molecolare:351.4AMAROGENTIN
CAS:Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.Formula:C29H30O13Purezza:99.98% - ≥95%Colore e forma:SolidPeso molecolare:586.54MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formula:C26H37ClN6O2Purezza:98.19%Colore e forma:SolidPeso molecolare:501.07WH-4-025
CAS:<p>WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.</p>Formula:C39H38F3N7O5Purezza:99.41%Colore e forma:SolidPeso molecolare:741.76STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Formula:C19H10N2O3Purezza:97.14% - 98.8%Colore e forma:SolidPeso molecolare:314.29MK-3903
CAS:MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formula:C27H19ClN2O3Purezza:98.63% - 99.75%Colore e forma:SolidPeso molecolare:454.9Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormula:C19H18NO4Purezza:98.08% - 99.18%Colore e forma:SolidPeso molecolare:324.35Nepodin
CAS:Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.Formula:C13H12O3Purezza:97.9% - 99.12%Colore e forma:SolidPeso molecolare:216.23ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFormula:C19H16N2O2SPurezza:98.89% - 99.7%Colore e forma:SolidPeso molecolare:336.41Ginkgolide C
CAS:Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Formula:C20H24O11Purezza:99.71% - 99.98%Colore e forma:White PowderPeso molecolare:440.40Vaccarin
CAS:<p>Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.</p>Formula:C32H38O19Purezza:99.16% - 99.97%Colore e forma:SolidPeso molecolare:726.63
