PI3K
Gli inibitori di PI3K sono composti che bloccano l'attività delle fosfoinositide 3-chinasi (PI3K), una famiglia di enzimi coinvolti in una vasta gamma di processi cellulari, tra cui crescita, proliferazione, sopravvivenza e metabolismo. La via PI3K/Akt/mTOR è spesso disregolata nel cancro, rendendo PI3K un obiettivo chiave per la terapia oncologica. Gli inibitori di PI3K sono strumenti critici per studiare la trasduzione del segnale, la biologia del cancro e lo sviluppo di terapie mirate. Presso CymitQuimica, offriamo una varietà di inibitori di PI3K per supportare la tua ricerca nella segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 231 prodotti di "PI3K"
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Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formula:C21H24ClN7OPurezza:97.04%Colore e forma:SolidPeso molecolare:425.91Ref: TM-T7015
1mg46,00€2mg59,00€5mg93,00€10mg131,00€25mg219,00€50mg350,00€100mg505,00€1mL*10mM (DMSO)92,00€SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purezza:99.42% - 99.79%Colore e forma:SolidPeso molecolare:443.85PIK-90
CAS:<p>PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .</p>Formula:C18H17N5O3Purezza:98.25% - ≥95%Colore e forma:SolidPeso molecolare:351.36A66
CAS:A66 is a specific and effective p110α inhibitor(IC50=32 nM).Formula:C17H23N5O2S2Purezza:99.51% - ≥95%Colore e forma:SolidPeso molecolare:393.53Ref: TM-T2418
2mg34,00€5mg52,00€10mg79,00€25mg137,00€50mg234,00€100mg344,00€200mg485,00€1mL*10mM (DMSO)52,00€Linperlisib
CAS:Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3KδFormula:C28H37FN6O5SPurezza:99.01%Colore e forma:SolidPeso molecolare:588.69Ref: TM-T6330
1mg34,00€2mg46,00€5mg66,00€10mg90,00€25mg192,00€50mg295,00€100mg462,00€1mL*10mM (DMSO)87,00€Vps34-IN-4
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formula:C21H25N7OPurezza:98.6%Colore e forma:SolidPeso molecolare:391.47Ref: TM-T7944
1mg66,00€5mg144,00€10mg227,00€25mg399,00€50mg567,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)159,00€CAY10505
CAS:CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Formula:C14H8FNO3SPurezza:99.69% - 99.74%Colore e forma:SolidPeso molecolare:289.28Ref: TM-T6433
10mg35,00€25mg56,00€50mg92,00€100mg153,00€200mg216,00€500mg369,00€1mL*10mM (DMSO)40,00€GDC-0326
CAS:GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).Formula:C19H22N6O3Purezza:99.35% - >99.99%Colore e forma:SolidPeso molecolare:382.42Ref: TM-T3985
1mg35,00€2mg49,00€5mg95,00€10mg155,00€25mg255,00€50mg406,00€100mg592,00€1mL*10mM (DMSO)94,00€AZD8186
CAS:AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).Formula:C24H25F2N3O4Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:457.47Ref: TM-T6773
2mg46,00€5mg66,00€10mg99,00€25mg168,00€50mg304,00€100mg505,00€500mg1.121,00€1mL*10mM (DMSO)72,00€Selective PI3Kδ Inhibitor 1
CAS:Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).Formula:C23H20FN7OPurezza:97.96%Colore e forma:SolidPeso molecolare:429.45Pilaralisib analogue
CAS:Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.Formula:C21H16N6O2S2Purezza:99.3% - 99.72%Colore e forma:SolidPeso molecolare:448.52Ref: TM-T2377
2mg38,00€5mg55,00€10mg88,00€25mg139,00€50mg216,00€100mg374,00€200mg485,00€1mL*10mM (DMSO)87,00€AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Formula:C22H24N4O4Purezza:99.87% - 99.95%Colore e forma:SolidPeso molecolare:408.45PIK-293
CAS:PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ.Formula:C22H19N7OPurezza:99.88%Colore e forma:SolidPeso molecolare:397.43Ref: TM-T3348
1mg48,00€2mg65,00€5mg96,00€10mg153,00€25mg274,00€50mg416,00€100mg603,00€1mL*10mM (DMSO)105,00€ETP-45658
CAS:ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).Formula:C16H17N5O2Purezza:99.14%Colore e forma:SolidPeso molecolare:311.34Ref: TM-T25399
1mg52,00€5mg111,00€10mg175,00€25mg316,00€50mg512,00€100mg747,00€1mL*10mM (DMSO)124,00€Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formula:C30H23N5OPurezza:97.64% - 99.85%Colore e forma:SolidPeso molecolare:469.54Pectolinarin
CAS:Pectolinarin is a Cirsium isolate with anti-inflammatory activity.Formula:C29H34O15Purezza:98% - 99.79%Colore e forma:SolidPeso molecolare:622.57MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurezza:97.6% - >99.99%Colore e forma:SolidPeso molecolare:478.33Ref: TM-T4296
1mg64,00€2mg95,00€5mg170,00€10mg274,00€25mg464,00€50mg640,00€100mg847,00€200mg1.159,00€1mL*10mM (DMSO)180,00€Pictilisib
CAS:Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formula:C23H27N7O3S2Purezza:98.69% - 99.97%Colore e forma:SolidPeso molecolare:513.64Sincalide
CAS:Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a cholecystokinin fragment.Formula:C49H62N10O16S3Purezza:98.32%Colore e forma:SolidPeso molecolare:1143.27IC-87114
CAS:IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).Formula:C22H19N7OPurezza:99.30% - >99.99%Colore e forma:SolidPeso molecolare:397.43
