Composti policiclici

<p>Applications 2-Amino-6-hydroxy-8-mercaptopurine (cas# 6324-72-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 5,6-Dihydroxyindole is an intermediate in melanogenesis, the production of melanin which is found in our skin, eyes, hair, and inner ear.<br>References S. Ito., et al.: Photochem. Photobiol., 84, 582-92 (2008);<br></p>

<p>Applications 1,3-Diiminoisoindoline is a useful compound in the production of colouring compositions. Dyes and metabolites.<br>References Matsumoto, T., et al.: PCT Int. Appl. (2020), WO 2020218262 A1<br></p>

<p>Applications Tricyclene, is one of the main constituent of many essential oils having antioxidant activities.<br>References Tamta, A., et al.: Cogent Chemistry, Vol.2, issue1 (2016);<br></p>

<p>Applications 3-Bicyclo[3.2.1]octanone is used as a reactant in the synthesis of polycyclic acid derivatives as selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).<br>References Ye, X., et. al.: Bioorg. Med. Chem. Lett., 21, 6699 (2011)<br></p>

<p>Applications Indoleacetic Acid is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.<br></p>

<p>Applications A metabolite of 6-Mercaptopurine (M225450).<br>References Zimm, S., et al.: Biochem. Pharmacol., 33, 4089 (1984), Lennard, L., et al.: Clin. Pharmacol. Ther., 46, 149 (1989), Knoester, P., et al.: Anticancer Res., 13, 1795 (1993), McLeod, H., et al.: Leukemia, 14, 567 (2000),<br></p>

<p>Applications Indole-3-acetamide is a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.<br>References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010)<br></p>

<p>Applications Methyl Oxindole-6-carboxylate is an intermediate used to prepare BIBF 1120, an indolinone as triple angiokinase inhibitors.<br>References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009)<br></p>

<p>Applications 2-Chloro-6-(2-hydroxybenzylamino)-9-isopropylpurine (cas# 500568-72-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE (cas# 5439-14-5) is a useful research chemical.<br></p>

<p>Applications Isoquinoline is used in the synthesis of nitrated indenoisoquinolines as a potent topoisomerase I inhibitor.This compound is a contaminant of emerging concern (CECs).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Morrell, A., et. al.: J. Med. Chem., 49, 7740 (2006)<br></p>

<p>Applications 4'-Bromo-2,2':6',2''-terpyridine (cas# 149817-62-9) is a useful research chemical.<br></p>

<p>Applications 9,10-Dihydro-9-oxa-10-phosphaphenanthrene 10-Oxide is an high effective componant of flame retardant epoxy resins.<br>References Mao, W., et al.: Gongcheng Suliao Yingyong, 44, 104-109 (2016)<br></p>

<p>Applications 2-Butoxyquinoline-4-carboxylic Acid is used in the organic synthesis of o-(β-diethylaminoethyl)cinchoninaldoxime with local anesthetic activity<br>References Rossi, S., et al.: Farmaco, Edizione Scientifica, 34, 486 (1979)<br></p>

<p>Applications 2-BROMOPHENANTHRENE (cas# 62162-97-4) is a useful research chemical.<br></p>

<p>Applications 5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.<br>References Richter, J., et al.: J. Am. Chem. Soc., 129, 12857 (2007); Yeung, B., et al.: J. Med. Chem., 53, 5155 (2010);<br></p>

<p>Applications 6-​Benzyloxy-​7-​methoxy-​3,​4-​dihydro-​isoquinoline is a reactant used in the synthesis of VMAT2 imaging agents.<br>References Liu, C. et al.: Chiral., 25, 215 (2013);<br></p>

<p>Applications trans-Indole-3-acrylic Acid is a regent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize polyphenols.<br>References Madrigal-Carballo, S., et al.: Int Food Res J, 20, 2023-2034 (2013)<br></p>

<p>Stability Volatile<br>Applications 1,​1'-​Bicyclopentyl along with butanal mixtures are used to produce high density aviation fuel.<br>References Yang, J., et al.: Ind. Eng. Chem. Res., 54, 11825-11837 (2015)<br></p>

<p>Stability Light Sensitive<br>Applications 5,6-Dibromo-1,10,11,12,13,13-hexachloro-11-tricyclo[8.2.1.02,9]tridecene is a flame retardant and a standard for environmental testing and research.<br>References EPA. Method 1668, (EPA 821-R-00-002) (1999); Dodson, R. E., et al.: Environ. Sci. Technol. 51, 4860 (2017)<br></p>

<p>Applications 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (cas# 117685-48-0) is a useful research chemical.<br></p>

<p>Applications 6-Dimethylaminopurine-9-riboside (cas# 2620-62-4) is a compound useful in organic synthesis.<br>References Elion, G.B., et al.: JACS, 74, 411-414 (1952), Kelley, J.L., et al.: J. Med. Chem., 32, 1020-1024 (1989)<br></p>

<p>Applications 8-Hydroxyquinoline (cas# 148-24-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside) (cas# 39824-26-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Mercaptoindole (cas# 480-94-4) is a compound useful in organic synthesis.<br>References Harris, R.L.N.: Tetrahedron Letters, 51, 4465 (1969)<br></p>

<p>Applications 3,6-Diiodo-1H-indazole is used to prepare aryl-substituted indazole derivatives as modulators and inhibitors of protein kinases in the treatment of tumor growth, cellular proliferation, and angiogenesis.<br>References Kania, R., et al.: PCT Int. Appl., WO 2001002369 A2 20010111 (2001)<br></p>

<p>Applications 4,4'-Di-tert-butyl-2,2'-bipyridine acts as a reagent in the preparation, antiproliferative and cytotoxic activity of apoptotic ruthenium nitrogen heterocyclic complexes via combinatorial library synthesis.<br>References Mulcahy, S. P., et al.: Dalton Trans., 39, 177 (2010)<br></p>

<p>Applications 9-oxo-9H-Thioxanthene-4-carboxylic acid (cas# 51762-56-2) is a useful research chemical.<br></p>

<p>Applications 4-NITROQUINOLINE N-OXIDE (cas# 56-57-5) is a useful research chemical.<br></p>

<p>Applications Used in synthesis of 3-amino-5H-pyrido[4,3-b]indoles, carcinogenic .gamma.-carbolines.<br>References Akimoto, H., et al.: Bull. Chem. Soc. Jpn., 58, 123 (1985),<br></p>

<p>Applications 1,2,3,4-tetrahydro-1,2-dimethyl-4,8-isoquinolinediol, is a Tetrahydroisoquinoline derivative, that can be used for the synthesis of pharmaceutical drugs, containing tetrahydroisoquinoline skeleton.<br></p>

<p>Applications 8-Azaxanthine Monohydrate (cas# 59840-67-4) is a compound useful in organic synthesis.<br>References Balnk, U.H., et al.: JOC, 35, 4, 1131 (1970)<br></p>

<p>Applications 1,1’-Bicyclohexyl is a hydrocarbon component present in diesel fuel.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Patino, P. et al.: Energy. Fuel., 16, 1470 (2002); Shokri, S. et al.: Chem. Tech., An Ind. J., 1, 119 (2006);<br></p>

<p>Applications Indazolone derivative.<br></p>

<p>Applications Intermediate in the preparation of P2X7 antagonists<br>References Donnelly-Roberts, D., et al.: Neuropharmacol., 56, 223 (2009), Perez-Medrano, A., et al.: J. Med. Chem., 52, 3366 (2009),<br></p>

<p>Applications 1-Ethyl-2,3,3-trimethylindolenium-5-sulfonate (cas# 146368-07-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Pyridoxamine Dihydrochloride (cas# 524-36-7) is a compound useful in organic synthesis.<br></p>

<p>Applications A useful intermediate for drug discovery research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Caldwell, J., et al.: Tet. Lett., 48, 1527 (2007)<br></p>

<p>Applications Ethyl Indole-3-acetate is a compound used in the synthesis of 9H-Pyrrolo[1,2-α]Indoles via Michael Addition-Condensation with α,β-Unsaturated Ketimines.<br>References Zhang, M., et al.: J. Heterocyclic Chem. (2016)<br></p>

<p>Applications 6-Benzylaminopurine can be used as reagent/reactant in pharmacological activity and synthesis preparation for modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71.<br>References Drenichev, M., S.: Eur. J. Med. Chem., 111, 84-94 (2016);<br></p>

<p>Applications 3-BROMOPHENANTHRENE (cas# 715-50-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications A naturally occurring purine derivative. Pharmaceuticals, Intermediates &amp; Fine Chemicals<br>References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),<br></p>

<p>Applications 6-Chloroisatin (cas# 6341-92-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Ethyl-1,2-dihydro-2,2,4-trimethyl-7-quinolinol is a reagent used in the preparation of fluorescent dyes and can be applied toward labeling of biological macromolecules.<br>References Liu, W., et.al., Faming Zhuanli Shenqing, 21, (2020);<br></p>

<p>Stability Hygroscopic<br>Applications 3-Amino-3-azabicyclo[3,3,0]octane is used as a reactant in the synthesis of Gliclazide (G409875), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972); Holmes, B., et al.: Drugs, 27, 301 (1984)<br></p>

<p>Applications tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate (cas# 203661-69-2) is a useful research chemical.<br></p>

<p>Applications 5,6,7,8-Tetrahydroquinoline (cas# 10500-57-9) is a useful research chemical.<br></p>

<p>Impurity Famciclovir USP Related Compound F<br>Applications Famciclovir USP Related Compound F<br></p>